UniProt P53355
Death-associated protein kinase 1 (P53355)
Death-associated protein kinase 1 (UniProt P53355), EC 2.7.11.1: 115 experimental structures and 1 predicted model on GenesisL1, 14 ligands bound, 16 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P53355
- Protein
- Death-associated protein kinase 1
- EC
- 2.7.11.1
- Experimental structures
- 115
- Predicted models
- 1
- Ligands
- 14
- Pockets
- 16 · 9 records with a druggable one
Structures
116 records of P53355 in the MolNFT archive: 115 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1IG1 | 1.8A X-Ray structure of ternary complex of a catalytic domain of death-associated protein kinase… | x-ray diffraction | A | — | — |
| 1IG1 | 1.8A X-ray structure of ternary complex of a catalytic domain of death-associated protein kinase… | x-ray diffraction | A | — | — |
| 1JKK | 2.4A X-ray structure of ternary complex of a catalytic domain of death-associated protein kinase… | x-ray diffraction | A | — | — |
| 1JKK | 2.4A X-ray structure of ternary complex of a catalytic domain of death-associated protein kinase… | x-ray diffraction | A | — | — |
| 1JKL | 1.6A X-ray structure of binary complex of a catalytic domain of death-associated protein kinase… | x-ray diffraction | A | — | — |
| 1JKL | 1.6A X-ray structure of binary complex of a catalytic domain of death-associated protein kinase… | x-ray diffraction | A | — | — |
| 1JKS | 1.5A X-ray structure of apo form of a catalytic domain of death-associated protein kinase | x-ray diffraction | A | — | — |
| 1JKS | 1.5A X-ray structure of apo form of a catalytic domain of death-associated protein kinase | x-ray diffraction | A | — | — |
| 1JKT | Tetragonal crystal form of a catalytic domain of death-associated protein kinase | x-ray diffraction | A, B | — | — |
| 1JKT | Tetragonal crystal form of a catalytic domain of death-associated protein kinase | x-ray diffraction | A, B | — | — |
| 1P4F | Death associated protein kinase catalytic domain with bound inhibitor fragment | x-ray diffraction | A | — | — |
| 1P4F | Death associated protein kinase catalytic domain with bound inhibitor fragment | x-ray diffraction | A | — | — |
| 1WVW | Crystal structures of kinase domain of DAP kinase in complex with small molecular inhibitors | x-ray diffraction | A | — | — |
| 1WVW | Crystal structures of kinase domain of dap kinase in complex with small molecular inhibitors | x-ray diffraction | A | — | — |
| 1WVX | Crystal structures of kinase domain of DAP kinase in complex with small molecular inhibitors | x-ray diffraction | A | — | — |
| 1WVX | Crystal structures of kinase domain of dap kinase in complex with small molecular inhibitors | x-ray diffraction | A | — | — |
| 1WVY | Crystal structures of kinase domain of DAP kinase in complex with small molecular inhibitors | x-ray diffraction | A | — | — |
| 1WVY | Crystal structures of kinase domain of dap kinase in complex with small molecular inhibitors | x-ray diffraction | A | — | — |
| 1YR5 | 1.7-A structure of calmodulin bound to a peptide from DAP kinase | x-ray diffraction | B | — | — |
| 1YR5 | 1.7-a structure of calmodulin bound to a peptide from dap kinase | x-ray diffraction | B | — | — |
| 2W4J | X-ray structure of a DAP-Kinase 2-277 | x-ray diffraction | A | — | — |
| 2W4J | X-ray structure of a dap-kinase 2-277 | x-ray diffraction | A | — | — |
| 2W4K | X-ray structure of a DAP-Kinase 2-302 | x-ray diffraction | A | — | — |
| 2W4K | X-ray structure of a dap-kinase 2-302 | x-ray diffraction | A | — | — |
| 2X0G | X-ray structure of a dap-kinase calmodulin complex | x-ray diffraction | A | — | — |
| 2X0G | X-ray structure of a dap-kinase calmodulin complex | x-ray diffraction | A | — | — |
| 2XUU | Crystal structure of a DAP-kinase 1 mutant | x-ray diffraction | A | — | — |
| 2XUU | Crystal structure of a dap-kinase 1 mutant | x-ray diffraction | A | — | — |
| 2XZS | Death associated protein kinase 1 residues 1-312 | x-ray diffraction | A, B | — | — |
| 2XZS | Death associated protein kinase 1 residues 1-312 | x-ray diffraction | A, B | — | — |
| 2Y0A | Structure of DAPK1 construct residues 1-304 | x-ray diffraction | A | — | — |
| 2Y0A | Structure of DAPK1 construct residues 1-304 | x-ray diffraction | A | — | — |
| 2Y4P | Dimeric structure of DAPK-1 catalytic domain | x-ray diffraction | A, B, C, D | — | — |
| 2Y4P | Dimeric structure of dapk-1 catalytic domain | x-ray diffraction | A, B, C, D | — | — |
| 2Y4V | Crystal structure of human calmodulin in complex with a dap kinase-1 mutant (W305Y) peptide | x-ray diffraction | B | — | — |
| 2Y4V | Crystal structure of human calmodulin in complex with a dap kinase-1 mutant (W305Y) peptide | x-ray diffraction | B | — | — |
| 2YAK | Structure of death-associated protein Kinase 1 (dapk1) in complex with a ruthenium octasporine… | x-ray diffraction | A | — | — |
| 2YAK | Structure of death-associated protein kinase 1 (DAPK1) in complex with a ruthenium octasporine… | x-ray diffraction | A | — | — |
| 3DFC | Crystal structure of a glycine-rich loop mutant of the death associated protein kinase catalytic… | x-ray diffraction | B | — | — |
| 3DFC | Crystal structure of a glycine-rich loop mutant of the death associated protein kinase catalytic… | x-ray diffraction | B | — | — |
| 3DGK | Crystal structure of a glycine-rich loop mutant of the death associated protein kinase catalytic… | x-ray diffraction | A | — | — |
| 3DGK | Crystal structure of a glycine-rich loop mutant of the death associated protein kinase catalytic… | x-ray diffraction | A | — | — |
| 3EH9 | Crystal structure of death associated protein kinase complexed with ADP | x-ray diffraction | A | — | — |
| 3EH9 | Crystal structure of death associated protein kinase complexed with ADP | x-ray diffraction | A | — | — |
| 3EHA | Crystal structure of death associated protein kinase complexed with AMPPNP | x-ray diffraction | A | — | — |
| 3EHA | Crystal structure of death associated protein kinase complexed with amppnp | x-ray diffraction | A | — | — |
| 3F5G | Crystal structure of death associated protein kinase in complex with ADP and Mg2+ | x-ray diffraction | A | — | — |
| 3F5G | Crystal structure of death associated protein kinase in complex with ADP and MG2+ | x-ray diffraction | A | — | — |
| 3F5U | Crystal structure of the death associated protein kinase in complex with AMPPNP and Mg2+ | x-ray diffraction | A | — | — |
| 3F5U | Crystal structure of the death associated protein kinase in complex with amppnp and MG2+ | x-ray diffraction | A | — | — |
| 3GU4 | Crystal structure of DAPKQ23V-AMPPNP | x-ray diffraction | A | — | — |
| 3GU4 | Crystal structure of DAPKQ23V-amppnp | x-ray diffraction | A | — | — |
| 3GU5 | Crystal structure of DAPKQ23V-AMPPNP-Mg2+ | x-ray diffraction | A | — | — |
| 3GU5 | Crystal structure of DAPKQ23V-amppnp-MG2+ | x-ray diffraction | A | — | — |
| 3GU6 | Crystal structure of DAPKQ23V-ADP | x-ray diffraction | A | — | — |
| 3GU6 | Crystal structure of DAPKQ23V-ADP | x-ray diffraction | A | — | — |
| 3GU7 | Crystal structure of DAPKQ23V-ADP-Mg2+ | x-ray diffraction | A | — | — |
| 3GU7 | Crystal structure of DAPKQ23V-ADP-MG2+ | x-ray diffraction | A | — | — |
| 3GU8 | Crystal structure of DAPKL93G with N6-cyclopentyladenosine | x-ray diffraction | A | — | — |
| 3GU8 | Crystal structure of DAPKL93G with N6-cyclopentyladenosine | x-ray diffraction | A | — | — |
56 records more on the page itself.
Ligands
- SO4 · Sulfate ion · in 9 records
- STL · Resveratrol · in 3 records
- BR · Bromide ion · in 2 records
- CL · Chloride ion · in 2 records
- PIT · Piceatannol · in 2 records
- 9TF · Purpurin · in 1 record
- A1L2V · (~{E})-1-[2,4-bis(oxidanyl)phenyl]-3-(3-chloranyl-4-oxidanyl-phenyl)prop-2-en-1-one · in 1 record
- A1L2W · (~{E})-1-[2,4-bis(oxidanyl)phenyl]-3-(3-bromanyl-4-oxidanyl-phenyl)prop-2-en-1-one · in 1 record
- GEN · Genistein · in 1 record
- KMP · 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one · in 1 record
- MG · Magnesium ion · in 1 record
- MRI · 2-[2,4-bis(oxidanyl)phenyl]-3,5,7-tris(oxidanyl) chromen-4-one · in 1 record
- NA · Sodium ion · in 1 record
- P5O · 5-[(~{E})-2-(3-methoxy-4-oxidanyl-phenyl)ethenyl]benzene-1,3-diol · in 1 record
Experiment against prediction
- 4UV0 chain A against the predicted model P53355: TM-score 0.99, RMSD 0.60 Å
- 4UV0 chain A against the predicted model P53355: TM-score 0.99, RMSD 0.60 Å
- 4B4L chain A against the predicted model P53355: TM-score 0.99, RMSD 0.64 Å
- 4B4L chain A against the predicted model P53355: TM-score 0.99, RMSD 0.64 Å
- 4TXC chain A against the predicted model P53355: TM-score 0.99, RMSD 0.84 Å
- 4TXC chain A against the predicted model P53355: TM-score 0.99, RMSD 0.84 Å
- 4TL0 chain A against the predicted model P53355: TM-score 0.99, RMSD 0.81 Å
- 4TL0 chain A against the predicted model P53355: TM-score 0.99, RMSD 0.81 Å
- 2Y0A chain A against the predicted model P53355: TM-score 0.99, RMSD 0.71 Å
- 2Y0A chain A against the predicted model P53355: TM-score 0.99, RMSD 0.71 Å
Elsewhere
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