UniProt P53041
Serine/threonine-protein phosphatase 5 (P53041)
Serine/threonine-protein phosphatase 5 (UniProt P53041), EC 3.1.3.16: 34 experimental structures on GenesisL1, 3 ligands bound, 8 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P53041
- Protein
- Serine/threonine-protein phosphatase 5
- EC
- 3.1.3.16
- Experimental structures
- 34
- Predicted models
- 0
- Ligands
- 3
- Pockets
- 8 · 1 record with a druggable one
Structures
34 records of P53041 in the MolNFT archive: 34 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1A17 | Tetratricopeptide repeats of protein phosphatase 5 | x-ray diffraction | A | — | — |
| 1A17 | Tetratricopeptide repeats of protein phosphatase 5 | x-ray diffraction | A | — | — |
| 1S95 | Structure of serine/threonine protein phosphatase 5 | x-ray diffraction | A, B | — | — |
| 1S95 | Structure of SERINE/THREONINE protein phosphatase 5 | x-ray diffraction | A, B | — | — |
| 1WAO | PP5 structure | x-ray diffraction | 1, 2, 3, 4 | — | — |
| 1WAO | PP5 structure | x-ray diffraction | 1, 2, 3, 4 | — | — |
| 2BUG | Solution structure of the TPR domain from Protein phosphatase 5 in complex with Hsp90 derived… | solution nmr | A | — | — |
| 2BUG | Solution structure of the tpr domain from protein phosphatase 5 in complex with HSP90 derived… | solution nmr | A | — | — |
| 3H60 | Catalytic domain of human Serine/Threonine Phosphatase 5 (PP5c)with two Mn2+ atoms | x-ray diffraction | A, B | — | — |
| 3H60 | Catalytic domain of human SERINE/THREONINE phosphatase 5 (PP5C)WITH two MN2+ atoms | x-ray diffraction | A, B | — | — |
| 3H61 | Catalytic domain of human Serine/Threonine Phosphatase 5 (PP5c) with two Mn2+ atoms originally… | x-ray diffraction | A, D | — | — |
| 3H61 | Catalytic domain of human SERINE/THREONINE phosphatase 5 (PP5C) with two MN2+ atoms originally… | x-ray diffraction | A, D | — | — |
| 3H62 | Catalytic domain of human Serine/Threonine Phosphatase 5 (PP5c) with two Mn2+ atoms complexed with… | x-ray diffraction | C, B | — | — |
| 3H62 | Catalytic domain of human SERINE/THREONINE phosphatase 5 (PP5C) with two MN2+ atoms complexed with… | x-ray diffraction | C, B | — | — |
| 3H63 | Catalytic domain of human Serine/Threonine Phosphatase 5 (PP5c) with two Mn2+ atoms originally… | x-ray diffraction | A, C | — | — |
| 3H63 | Catalytic domain of human SERINE/THREONINE phosphatase 5 (PP5C) with two MN2+ atoms originally… | x-ray diffraction | A, C | — | — |
| 3H64 | Catalytic domain of human Serine/Threonine Phosphatase 5 (PP5c) with two Mn2+ atoms complexed with… | x-ray diffraction | A, D | — | — |
| 3H64 | Catalytic domain of human SERINE/THREONINE phosphatase 5 (PP5C) with two MN2+ atoms complexed with… | x-ray diffraction | A, D | — | — |
| 3H66 | Catalytic domain of human Serine/Threonine Phosphatase 5 (PP5c) with two Zn2+ atoms | x-ray diffraction | A, B | — | — |
| 3H66 | Catalytic domain of human SERINE/THREONINE phosphatase 5 (PP5C) with two ZN2+ atoms | x-ray diffraction | A, B | — | — |
| 3H67 | Catalytic domain of human Serine/Threonine Phosphatase 5 (PP5c)with two Zn2+ atoms complexed with… | x-ray diffraction | A, D | — | — |
| 3H67 | Catalytic domain of human SERINE/THREONINE phosphatase 5 (PP5C)WITH two ZN2+ atoms complexed with… | x-ray diffraction | A, D | — | — |
| 3H68 | Catalytic domain of human Serine/Threonine Phosphatase 5 (PP5c)with two Zn2+ atoms originally… | x-ray diffraction | A, D | — | — |
| 3H68 | Catalytic domain of human SERINE/THREONINE phosphatase 5 (PP5C)WITH two ZN2+ atoms originally… | x-ray diffraction | A, D | — | — |
| 3H69 | Catalytic domain of human Serine/Threonine Phosphatase 5 (PP5c) with two Zn2+ atoms complexed with… | x-ray diffraction | A, D | — | — |
| 3H69 | Catalytic domain of human SERINE/THREONINE phosphatase 5 (PP5C) with two ZN2+ atoms complexed with… | x-ray diffraction | A, D | — | — |
| 4ZVZ | Co-crystal structures of PP5 in complex with 5-methyl-7- OXABICYCLO[2.2.1]HEPTANE-2,3-dicarboxylic… | x-ray diffraction | A, B, C, D | — | — |
| 4ZX2 | Co-crystal structures of PP5 in complex with 5-methyl-7- OXABICYCLO[2.2.1]HEPTANE-2,3-dicarboxylic… | x-ray diffraction | A | — | — |
| 5HPE | Phosphatase domain of PP5 bound to a phosphomimetic CDC37 substrate peptide | x-ray diffraction | A | — | — |
| 5UI1 | Crystal Structure of Human Protein Phosphatase 5C (PP5C) in complex with a triazole inhibitor | x-ray diffraction | A, B, C, D | MN, 8D4 | 8 (best 0.70) |
| 5UI1 | Crystal structure of human protein phosphatase 5C (PP5C) in complex with a triazole inhibitor | x-ray diffraction | A, B, C, D | MN, 8D4 | — |
| 5WG8 | Structure of PP5C with lb-100; 7-OXABICYCLO[2.2.1]HEPTANE-2,3- dicarbonyl moiety modeled in the… | x-ray diffraction | A | MN, LB1 | — |
| 7ZR6 | CryoEM structure of HSP90-CDC37-BRAF(V600E)-PP5(open) complex | electron microscopy | P | — | — |
| P53041 | AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein phosphatase 5 (P53041) | — | — | — |
Ligands
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.