UniProt P52179
Myomesin-1 (P52179)
Myomesin-1 (UniProt P52179): 18 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 38 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P52179
- Protein
- Myomesin-1
- Experimental structures
- 18
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 38 · 4 records with a druggable one
Structures
19 records of P52179 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2R15 | Crystal structure of the myomesin domains 12 and 13 | x-ray diffraction | A, B | — | 1 (best 0.28) |
| 2R15 | Crystal structure of the myomesin domains 12 and 13 | x-ray diffraction | A, B | — | 1 (best 0.28) |
| 2Y23 | Crystal structure of the myomesin domains MY9-MY11 | x-ray diffraction | A | — | 1 (best 0.35) |
| 2Y23 | Crystal structure of the myomesin domains MY9-MY11 | x-ray diffraction | A | — | 1 (best 0.35) |
| 2Y25 | Crystal structure of the myomesin domains My11-My13 | x-ray diffraction | A, B, C, D | — | 6 (best 0.49) |
| 2Y25 | Crystal structure of the myomesin domains MY11-MY13 | x-ray diffraction | A, B, C, D | — | 6 (best 0.49) |
| 3RBS | Crystal structure of the myomesin domains 10 and 11 | x-ray diffraction | A | NO3 | 1 (best 0.33) |
| 3RBS | Crystal structure of the myomesin domains 10 and 11 | x-ray diffraction | A | NO3 | 1 (best 0.33) |
| 5FM4 | Structure of the C-terminally extended domain My4 of human myomesin (space group P21) | x-ray diffraction | A, B, C, D, E, F | — | 3 (best 0.83) |
| 5FM4 | Structure of the C-terminally extended domain MY4 of human myomesin (space group P21) | x-ray diffraction | A, B, C, D, E, F | — | — |
| 5FM5 | Crystal structure of the myomesin:obscurin-like-1 complex | x-ray diffraction | M, N | — | 6 (best 0.60) |
| 5FM5 | Crystal structure of the MYOMESIN:OBSCURIN-like-1 complex | x-ray diffraction | M, N | — | — |
| 5FM8 | Structure of the C-terminally extended domain My4 of human myomesin (space group P65) | x-ray diffraction | A, B, C, D | NI | 3 (best 0.61) |
| 5FM8 | Structure of the C-terminally extended domain MY4 of human myomesin (space group P65) | x-ray diffraction | A, B, C, D | — | — |
| 6T3O | Crystal structure of the human myomesin domain 10 | x-ray diffraction | A | AZI | — |
| 6T3O | Crystal structure of the human myomesin domain 10 | x-ray diffraction | A | AZI | — |
| 6ZVA | Crystal structure of My5 | x-ray diffraction | B, A | SO4 | — |
| 6ZVA | Crystal structure of MY5 | x-ray diffraction | B, A | SO4 | — |
| P52179 | AlphaFold monomer V2.0 prediction for myomesin-1 (P52179) | predicted | A | — | 8 (best 0.63) |
Ligands
Experiment against prediction
- 5FM8 chain D against the predicted model P52179: TM-score 0.98, RMSD 0.48 Å
- 5FM8 chain B against the predicted model P52179: TM-score 0.98, RMSD 0.48 Å
- 5FM8 chain C against the predicted model P52179: TM-score 0.98, RMSD 0.61 Å
- 5FM4 chain E against the predicted model P52179: TM-score 0.98, RMSD 0.59 Å
- 5FM4 chain A against the predicted model P52179: TM-score 0.97, RMSD 0.62 Å
- 5FM4 chain A against the predicted model P52179: TM-score 0.97, RMSD 0.62 Å
- 5FM4 chain B against the predicted model P52179: TM-score 0.97, RMSD 0.75 Å
- 5FM4 chain B against the predicted model P52179: TM-score 0.97, RMSD 0.75 Å
- 6T3O chain A against the predicted model P52179: TM-score 0.96, RMSD 0.86 Å
- 6T3O chain A against the predicted model P52179: TM-score 0.96, RMSD 0.86 Å
Elsewhere
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