UniProt P49951
Clathrin heavy chain 1 (P49951)
Clathrin heavy chain 1 (UniProt P49951): 34 experimental structures and 1 predicted model on GenesisL1, 41 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P49951
- Protein
- Clathrin heavy chain 1
- Experimental structures
- 34
- Predicted models
- 1
- Pockets
- 41 · 5 records with a druggable one
Structures
35 records of P49951 in the MolNFT archive: 34 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1B89 | Clathrin heavy chain proximal leg segment (bovine) | x-ray diffraction | A | — | — |
| 1B89 | Clathrin heavy chain proximal leg segment (bovine) | x-ray diffraction | A | — | — |
| 1UTC | Clathrin terminal domain complexed with TLPWDLWTT | x-ray diffraction | A, B | — | — |
| 1UTC | Clathrin terminal domain complexed with tlpwdlwtt | x-ray diffraction | A, B | — | — |
| 1XI4 | Clathrin D6 Coat | electron microscopy | A, B, C, D, E, F, G, H, I | — | — |
| 1XI4 | Clathrin D6 coat | electron microscopy | A, B, C, D, E, F, G, H, I | — | — |
| 1XI5 | Clathrin D6 coat with auxilin J-domain | electron microscopy | A, B, C, D, E, F, G, H, I | — | — |
| 1XI5 | Clathrin D6 coat with auxilin J-domain | electron microscopy | A, B, C, D, E, F, G, H, I | — | — |
| 3GC3 | Crystal Structure of Arrestin2S and Clathrin | x-ray diffraction | B | — | — |
| 3GC3 | Crystal structure of ARRESTIN2S and clathrin | x-ray diffraction | B | — | — |
| 3GD1 | Structure of an Arrestin/Clathrin complex reveals a novel clathrin binding domain that modulates… | x-ray diffraction | I | — | — |
| 3GD1 | Structure of an ARRESTIN/CLATHRIN complex reveals a novel clathrin binding domain that modulates… | x-ray diffraction | I | — | — |
| 3IYV | Clathrin D6 coat as full-length Triskelions | electron microscopy | A, B, C, D, E, F, G, H, I | — | — |
| 3IYV | Clathrin D6 coat as full-length triskelions | electron microscopy | A, B, C, D, E, F, G, H, I | — | — |
| 3LVG | Crystal structure of a clathrin heavy chain and clathrin light chain complex | x-ray diffraction | A, B, C | — | — |
| 3LVG | Crystal structure of a clathrin heavy chain and clathrin light chain complex | x-ray diffraction | A, B, C | — | — |
| 3LVH | Crystal structure of a clathrin heavy chain and clathrin light chain complex | x-ray diffraction | A, B, C | — | — |
| 3LVH | Crystal structure of a clathrin heavy chain and clathrin light chain complex | x-ray diffraction | A, B, C | — | — |
| 3QIL | Crystal structure analysis of the clathrin trimerization domain | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X | — | — |
| 3QIL | Crystal structure analysis of the clathrin trimerization domain | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X | — | — |
| 5M5R | Clathrin heavy chain N-terminal domain bound to beta2 adaptin clathrin box motif | x-ray diffraction | A | — | 2 (best 0.76) |
| 5M5R | Clathrin heavy chain N-terminal domain bound to BETA2 adaptin clathrin box motif | x-ray diffraction | A | — | — |
| 5M5S | Clathrin heavy chain N-terminal domain bound to amphiphysin clathrin-box motif | x-ray diffraction | A, B | — | — |
| 5M5S | Clathrin heavy chain N-terminal domain bound to amphiphysin clathrin- box motif | x-ray diffraction | A, B | — | — |
| 5M5T | Clathrin heavy chain N-terminal domain bound to a non-natural clathrin-box motif peptide (Amph4T1) | x-ray diffraction | A, B | — | 7 (best 0.83) |
| 5M5T | Clathrin heavy chain N-terminal domain bound to a non-natural clathrin-box motif peptide (AMPH4T1) | x-ray diffraction | A, B | — | — |
| 5M5U | Clathrin heavy chain N-terminal domain bound to a clathrin-box motif from hepatitis D virus large… | x-ray diffraction | A, B | — | — |
| 5M5U | Clathrin heavy chain N-terminal domain bound to a clathrin-box motif from hepatitis D virus large… | x-ray diffraction | A, B | — | — |
| 5M5V | Clathrin heavy chain N-terminal domain bound to a clathrin-box motif from hepatitis D virus large… | x-ray diffraction | A, B | — | 5 (best 0.82) |
| 5M5V | Clathrin heavy chain N-terminal domain bound to a clathrin-box motif from hepatitis D virus large… | x-ray diffraction | A, B | — | — |
| 5M61 | Clathrin heavy chain N-terminal domain bound to an extended amphiphysin clathrin-box motif | x-ray diffraction | A, B | — | 7 (best 0.85) |
| 5M61 | Clathrin heavy chain N-terminal domain bound to an extended amphiphysin clathrin-box motif | x-ray diffraction | A, B | — | — |
| 6WCJ | Asymmetric vertex of the clathrin minicoat cage | electron microscopy | A, C, D, L, M, G, H, I, K | — | 20 (best 0.84) |
| 6WCJ | Asymmetric vertex of the clathrin minicoat cage | electron microscopy | A, C, D, L, M, G, H, I, K | — | — |
| P49951 | AlphaFold monomer V2.0 prediction for clathrin heavy chain 1 (P49951) | predicted | A | — | — |
Experiment against prediction
- 5M5U chain A against the predicted model P49951: TM-score 0.99, RMSD 0.64 Å
- 5M5U chain A against the predicted model P49951: TM-score 0.99, RMSD 0.64 Å
- 3GC3 chain B against the predicted model P49951: TM-score 0.99, RMSD 0.62 Å
- 3GC3 chain B against the predicted model P49951: TM-score 0.99, RMSD 0.62 Å
- 3GD1 chain I against the predicted model P49951: TM-score 0.99, RMSD 0.63 Å
- 3GD1 chain I against the predicted model P49951: TM-score 0.99, RMSD 0.63 Å
- 5M5T chain A against the predicted model P49951: TM-score 0.99, RMSD 0.65 Å
- 5M5T chain A against the predicted model P49951: TM-score 0.99, RMSD 0.65 Å
- 5M5U chain B against the predicted model P49951: TM-score 0.99, RMSD 0.65 Å
- 5M5U chain B against the predicted model P49951: TM-score 0.99, RMSD 0.65 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.