UniProt P49792
E3 SUMO-protein ligase RanBP2 (P49792)
E3 SUMO-protein ligase RanBP2 (UniProt P49792), EC 2.3.2.-: 53 experimental structures on GenesisL1, 3 ligands bound, 108 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P49792
- Protein
- E3 SUMO-protein ligase RanBP2
- EC
- 2.3.2.-
- Experimental structures
- 53
- Predicted models
- 0
- Ligands
- 3
- Pockets
- 108 · 8 records with a druggable one
Structures
53 records of P49792 in the MolNFT archive: 53 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1RRP | Structure of the ran-gppnhp-RANBD1 complex | x-ray diffraction | B, D | — | — |
| 1RRP | Structure of the ran-gppnhp-RANBD1 complex | x-ray diffraction | B, D | — | — |
| 1XKE | Solution structure of the second Ran-binding domain from human RanBP2 | solution nmr | A | — | — |
| 1XKE | Solution structure of the second ran-binding domain from human RANBP2 | solution nmr | A | — | — |
| 1Z5S | Crystal structure of a complex between UBC9, SUMO-1, RANGAP1 and NUP358/RANBP2 | x-ray diffraction | D | — | — |
| 1Z5S | Crystal structure of a complex between UBC9, sumo-1, RANGAP1 and NUP358/RANBP2 | x-ray diffraction | D | — | — |
| 3UIN | Complex between human RanGAP1-SUMO2, UBC9 and the IR1 domain from RanBP2 | x-ray diffraction | D | — | — |
| 3UIN | Complex between human RANGAP1-SUMO2, UBC9 and the IR1 domain from RANBP2 | x-ray diffraction | D | — | — |
| 3UIO | Complex between human RanGAP1-SUMO2, UBC9 and the IR1 domain from RanBP2 containing IR2 Motif II | x-ray diffraction | D | — | — |
| 3UIO | Complex between human RANGAP1-SUMO2, UBC9 and the IR1 domain from RANBP2 containing IR2 motif II | x-ray diffraction | D | — | — |
| 3UIP | Complex between human RanGAP1-SUMO1, UBC9 and the IR1 domain from RanBP2 containing IR2 Motif II | x-ray diffraction | D | — | — |
| 3UIP | Complex between human RANGAP1-SUMO1, UBC9 and the IR1 domain from RANBP2 containing IR2 motif II | x-ray diffraction | D | — | — |
| 4GA0 | Structure of the N-terminal domain of Nup358 | x-ray diffraction | A | — | — |
| 4GA0 | Structure of the N-terminal domain of NUP358 | x-ray diffraction | A | — | — |
| 4I9Y | Structure of the C-terminal domain of Nup358 | x-ray diffraction | A, B, C, D, E, F | — | — |
| 4I9Y | Structure of the C-terminal domain of NUP358 | x-ray diffraction | A, B, C, D, E, F | — | — |
| 4L6E | Crystal Structure of the RanBD1 fourth domain of E3 SUMO-protein ligase RanBP2. Northeast… | x-ray diffraction | A | — | — |
| 4L6E | Crystal structure of the RANBD1 fourth domain of E3 sumo-protein ligase RANBP2. northeast… | x-ray diffraction | A | — | — |
| 4LQW | Crystal structure of HIV-1 capsid N-terminal domain in complex with NUP358 cyclophilin | x-ray diffraction | A, B | — | — |
| 4LQW | Crystal structure of HIV-1 capsid N-terminal domain in complex with NUP358 cyclophilin | x-ray diffraction | A, B | — | — |
| 5CLL | Truncated ran wild type in complex with GDP-bef and RANBD1 | x-ray diffraction | B, D | — | — |
| 5CLQ | Ran Y39A in complex with gppnhp and RANBD1 | x-ray diffraction | B, D | — | — |
| 7MNJ | Crystal structure of the N-terminal domain of NUP358/RanBP2 (residues 145-673) | x-ray diffraction | A, B, C | — | 20 (best 0.79) |
| 7MNJ | Crystal structure of the N-terminal domain of NUP358/RANBP2 (residues 145-673) | x-ray diffraction | A, B, C | — | — |
| 7MNK | Crystal structure of the tetramerization element of NUP358/RanBP2 (residues 805-832) | x-ray diffraction | A, B, C, D | SO4 | — |
| 7MNK | Crystal structure of the tetramerization element of NUP358/RANBP2 (residues 805-832) | x-ray diffraction | A, B, C, D | SO4 | — |
| 7MNL | Crystal structure of the N-terminal domain of NUP358/RanBP2 (residues 1-752) in complex with Fab… | x-ray diffraction | A, B | — | — |
| 7MNL | Crystal structure of the N-terminal domain of NUP358/RANBP2 (residues 1-752) in complex with Fab… | x-ray diffraction | A, B | — | — |
| 7MNM | Crystal structure of the N-terminal domain of NUP358/RanBP2 (residues 1-752) T585M mutant in… | x-ray diffraction | A, B | — | 14 (best 0.81) |
| 7MNM | Crystal structure of the N-terminal domain of NUP358/RANBP2 (residues 1-752) T585M mutant in… | x-ray diffraction | A, B | — | — |
| 7MNN | Crystal structure of the N-terminal domain of NUP358/RanBP2 (residues 1-752) T653I mutant in… | x-ray diffraction | A, B | — | 13 (best 0.82) |
| 7MNN | Crystal structure of the N-terminal domain of NUP358/RANBP2 (residues 1-752) T653I mutant in… | x-ray diffraction | A, B | — | — |
| 7MNO | Crystal structure of the N-terminal domain of NUP358/RANBP2 (residues 1-752) I656V mutant in… | x-ray diffraction | A, B | — | — |
| 7MNP | Crystal Structure of the ZnF2 of Nucleoporin NUP358/RanBP2 in complex with Ran-GDP | x-ray diffraction | B, D | ZN, GDP | 2 (best 0.77) |
| 7MNP | Crystal structure of the ZNF2 of nucleoporin NUP358/RANBP2 in complex with ran-GDP | x-ray diffraction | B, D | ZN, GDP | — |
| 7MNQ | Crystal structure of the ZNF2 of nucleoporin NUP358/RANBP2 in complex with ran-GDP | x-ray diffraction | B | ZN | — |
| 7MNR | Crystal Structure of the ZnF3 of Nucleoporin NUP358/RanBP2 in complex with Ran-GDP | x-ray diffraction | B | ZN | — |
| 7MNR | Crystal structure of the ZNF3 of nucleoporin NUP358/RANBP2 in complex with ran-GDP | x-ray diffraction | B | ZN | — |
| 7MNS | Crystal Structure of the ZnF4 of Nucleoporin NUP358/RanBP2 in complex with Ran-GDP | x-ray diffraction | B | ZN | — |
| 7MNS | Crystal structure of the ZNF4 of nucleoporin NUP358/RANBP2 in complex with ran-GDP | x-ray diffraction | B | ZN | — |
| 7MNT | Crystal structure of the ZNF5 or ZNF6 of nucleoporin NUP358/RANBP2 in complex with ran-GDP | x-ray diffraction | B, D | ZN | — |
| 7MNU | Crystal Structure of the ZnF7 of Nucleoporin NUP358/RanBP2 in complex with Ran-GDP | x-ray diffraction | B | ZN | — |
| 7MNU | Crystal structure of the ZNF7 of nucleoporin NUP358/RANBP2 in complex with ran-GDP | x-ray diffraction | B | ZN | — |
| 7MNV | Crystal Structure of the ZnF8 of Nucleoporin NUP358/RanBP2 in complex with Ran-GDP | x-ray diffraction | B | ZN | 1 (best 0.38) |
| 7MNV | Crystal structure of the ZNF8 of nucleoporin NUP358/RANBP2 in complex with ran-GDP | x-ray diffraction | B | ZN | — |
| 7MNW | Crystal Structure of Nup358/RanBP2 Ran-binding domain 1 in complex with Ran-GPPNHP | x-ray diffraction | B, D, F, H | — | 17 (best 0.79) |
| 7MNW | Crystal structure of NUP358/RANBP2 ran-binding domain 1 in complex with ran-gppnhp | x-ray diffraction | B, D, F, H | — | — |
| 7MNX | Crystal Structure of Nup358/RanBP2 Ran-binding domain 2 in complex with Ran-GPPNHP | x-ray diffraction | B, D, F, H, J, L | — | 18 (best 0.83) |
| 7MNX | Crystal structure of NUP358/RANBP2 ran-binding domain 2 in complex with ran-gppnhp | x-ray diffraction | B, D, F, H, J, L | — | — |
| 7MNY | Crystal structure of NUP358/RANBP2 ran-binding domain 3 in complex with ran-gppnhp | x-ray diffraction | B, D, F, H, J, L | — | — |
| 7MNZ | Crystal Structure of Nup358/RanBP2 Ran-binding domain 4 in complex with Ran-GPPNHP | x-ray diffraction | B, D, F, H, J, L | — | 16 (best 0.78) |
| 7MNZ | Crystal structure of NUP358/RANBP2 ran-binding domain 4 in complex with ran-gppnhp | x-ray diffraction | B, D, F, H, J, L | — | — |
| 9B62 | Human RANBP2/RAN(GTP)/RANGAP1-SUMO1/UBC9/CRM1/RAN(GTP) - composite map and model | electron microscopy | E | — | 7 (best 0.70) |
Ligands
Elsewhere
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