UniProt P48651
Phosphatidylserine synthase 1 (P48651)
Phosphatidylserine synthase 1 (UniProt P48651), EC 2.7.8.29: 3 experimental structures on GenesisL1, 6 ligands bound, 21 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P48651
- Protein
- Phosphatidylserine synthase 1
- EC
- 2.7.8.29
- Experimental structures
- 3
- Predicted models
- 0
- Ligands
- 6
- Pockets
- 21 · 2 records with a druggable one
Structures
3 records of P48651 in the MolNFT archive: 3 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 9B4E | Structure of wild type human PSS1 | electron microscopy | A, B | P5S, LBN, A1AIS, 6OU, CA | 11 (best 0.84) |
| 9B4G | Structure of inhibitor-bound human PSS1 | electron microscopy | A, B | P5S, LBN, A1AIS, 6OU, CA, A1AIT | 10 (best 0.85) |
| P48651 | AlphaFold monomer V2.0 prediction for phosphatidylserine synthase 1 (P48651) | — | — | — |
Ligands
- 6OU · [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate · in 2 records
- A1AIS · (2R)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dihexadecanoate · in 2 records
- CA · Calcium ion · in 2 records
- LBN · 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine · in 2 records
- P5S · O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy) propyl]oxy}(hydroxy)phosphoryl]-L-serine · in 2 records
- A1AIT · (7P)-7-[(4S)-4-{4-[3,5-bis(trifluoromethyl)phenoxy]phenyl}-5-(2,2-difluoropropyl)-6-oxo-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl]-1,3-benzoxazol-2(3H)-one · in 1 record
Elsewhere
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