UniProt P40970
Serine palmitoyltransferase 2 (P40970)
Serine palmitoyltransferase 2 (UniProt P40970), EC 2.3.1.50: 4 experimental structures on GenesisL1, 4 ligands bound, 50 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P40970
- Protein
- Serine palmitoyltransferase 2
- EC
- 2.3.1.50
- Experimental structures
- 4
- Predicted models
- 0
- Ligands
- 4
- Pockets
- 50 · 3 records with a druggable one
Structures
4 records of P40970 in the MolNFT archive: 4 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8IAJ | Cryo-EM structure of the yeast SPT-ORM2 (ORM2-S3A) complex | electron microscopy | B, F | PLP, Z1T | 15 (best 0.87) |
| 8IAM | Cryo-EM structure of the yeast SPT-ORM2 (ORM2-S3D) complex | electron microscopy | B, F | PLP, Z1T | 20 (best 0.88) |
| 8QOG | Cryo-EM structure of the yeast SPT-Orm2-Monomer complex | electron microscopy | C | WAR, PLP, Q7G | 15 (best 0.88) |
| P40970 | AlphaFold monomer V2.0 prediction for serine palmitoyltransferase 2 (P40970) | — | — | — |
Ligands
- PLP · Pyridoxal-5'-phosphate · in 3 records
- Z1T · N-[(2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]tetracosanamide · in 2 records
- Q7G · 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta, 17beta,25r)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside · in 1 record
- WAR · ~{N}-[(2~{S},3~{S},4~{R})-1,3,4-tris(oxidanyl)octadecan-2-yl]heptacosanamide · in 1 record
Elsewhere
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