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Ligand · Q7G

Q7G · 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta, 17beta,25r)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside

Q7G, 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta, 17beta,25r)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside (C56 H92 O25, 1165.3 g/mol), in the MolNFT…

Component
Q7G
Formula
C56 H92 O25
Class
ligand
Structures
15
PDB entries
13

Binding sites

Q7G in 15 structures; the first of them:

  • 7K65 · Hedgehog receptor Patched (PTCH1) in complex with conformation selective nanobody TI23 · Q7G A1406 · binds ASN110, VAL111, GLU112, LEU114, TRP115, GLU136, ALA137, PHE139 and 30 more
  • 7TJ9 · Cryo-EM structure of the human Nax channel in complex with beta3 solved in GDN · Q7G A2418 · binds GLN236, ILE238, GLY239, VAL240, ILE242, PHE246, SER249, ILE250 and 18 more
  • 8AP6 · Trypanosoma brucei mitochondrial F1Fo ATP synthase dimer · Q7G E402 · binds GLY110, TYR111, ILE113, PRO114, TRP47, TRP51, TYR52
  • 8AP7 · membrane region of the Trypanosoma brucei mitochondrial ATP synthase dimer · Q7G E407 · binds GLY110, TYR111, ILE113, PRO114, TRP47, TRP51, TYR52
  • 8APB · rotational state 1b of the Trypanosoma brucei mitochondrial ATP synthase dimer · Q7G e406 · binds GLY110, TYR111, ILE113, PRO114, TRP47, TRP51, TYR52
  • 8APJ · rotational state 2d of Trypanosoma brucei mitochondrial ATP synthase · Q7G e407 · binds GLY110, TYR111, ILE113, PRO114, TRP47, TRP51, TYR52
  • 8APK · rotational state 3 of the Trypanosoma brucei mitochondrial ATP synthase dimer · Q7G e406 · binds GLY110, TYR111, ILE113, PRO114, TRP47, TRP51, TYR52
  • 8BEF · Cryo-EM structure of the Arabidopsis thaliana I+III2 supercomplex (CI membrane core) · Q7G H403 · binds ASP95, TYR96, MET98, MET172, TRP251, LEU252, PRO264, GLY265 and 15 more
  • 8BEL · Cryo-EM structure of the Arabidopsis thaliana I+III2 supercomplex (CIII membrane domain) · Q7G M410 · binds PRO292, LEU303, GLN359, SER362, LEU363, PHE366
  • 8IJL · Cyo-EM structure of wildtype non-gastric proton pump in the presence of Na+, AlF and ADP · Q7G A1112 · binds ILE804, VAL807, ALA808, THR893, ILE896
  • 8QEC · S. cerevisia Niemann-Pick type C protein NCR1 in GDN at pH 5.5 · Q7G A1202 · binds ASN165, PHE391, TYR392, GLN396, PHE439, PRO441, VAL448, GLU450 and 13 more
  • 8QOF · Cryo-EM structure of the yeast SPT-Orm2-Dimer complex · Q7G G602 · binds ILE119, VAL124, LYS125, GLY126, ASP137, HIS76, PHE80, MET83 and 6 more
  • 8QOG · Cryo-EM structure of the yeast SPT-Orm2-Monomer complex · Q7G C602 · binds LEU123, VAL124, LYS125, ASP137, HIS76, VAL77, ASP79, PHE80 and 6 more
  • 7K65 · Hedgehog receptor patched (PTCH1) in complex with conformation selective nanobody TI23 · Q7G A1406 · binds VAL111, LEU114, TRP115, ASN140, LEU143, LEU327, GLN347, MET349 and 22 more
  • 7TJ9 · Cryo-EM structure of the human nax channel in complex with BETA3 solved in gdn · Q7G A2418 · binds GLN236, GLY239, VAL240, ILE242, PHE246, SER249, ILE392, MET395 and 11 more

Residues it binds most

LEU 26, PHE 24, TYR 24, ILE 23, PRO 25, ALA 19, VAL 17, TRP 15, GLY 22, MET 10 (residue and the binding sites it lines).

Found with

  • CDL · Cardiolipin
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
  • ADP · Adenosine-5'-diphosphate
  • PC1 · 1,2-diacyl-sn-glycero-3-phosphocholine
  • MG · Magnesium ion
  • LMT · Dodecyl-beta-D-maltoside
  • ATP · Adenosine-5'-triphosphate
  • UTP · Uridine 5'-triphosphate
  • CLR · Cholesterol
  • PEE · 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
  • 3PE · 1,2-diacyl-sn-glycero-3-phosphoethanolamine
  • 3PH · 1,2-diacyl-glycerol-3-sn-phosphate

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