UniProt P34998
Corticotropin-releasing factor receptor 1,Lysozyme,Corticotropin-releasing factor receptor 1 (P34998)
Corticotropin-releasing factor receptor 1,Lysozyme,Corticotropin-releasing factor receptor 1 (UniProt P34998), EC 3.2.1.17: 15 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 20 pockets. Binding…
- UniProt
- P34998
- Protein
- Corticotropin-releasing factor receptor 1,Lysozyme,Corticotropin-releasing…
- EC
- 3.2.1.17
- Experimental structures
- 15
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 20 · 2 records with a druggable one
Structures
16 records of P34998 in the MolNFT archive: 15 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2L27 | NMR Structure of the ECD1 of CRF-R1 in complex with a peptide agonist | solution nmr | A | — | — |
| 2L27 | NMR structure of the ECD1 of crf-R1 in complex with a peptide agonist | solution nmr | A | — | — |
| 3EHS | Crystal structure of the extracellular domain of human corticotropin releasing factor receptor type… | x-ray diffraction | A | — | — |
| 3EHS | Crystal structure of the extracellular domain of human corticotropin releasing factor receptor type… | x-ray diffraction | A | — | — |
| 3EHT | Crystal structure of the extracellular domain of human corticotropin releasing factor receptor type… | x-ray diffraction | A | — | — |
| 3EHT | Crystal structure of the extracellular domain of human corticotropin releasing factor receptor type… | x-ray diffraction | A | — | — |
| 3EHU | Crystal structure of the extracellular domain of human corticotropin releasing factor receptor type… | x-ray diffraction | A, B | — | — |
| 3EHU | Crystal structure of the extracellular domain of human corticotropin releasing factor receptor type… | x-ray diffraction | A, B | — | — |
| 4K5Y | Crystal structure of human corticotropin-releasing factor receptor 1 (CRF1R) in complex with the… | x-ray diffraction | A, B, C | — | — |
| 4K5Y | Crystal structure of human corticotropin-releasing factor receptor 1 (CRF1R) in complex with the… | x-ray diffraction | A, B, C | — | — |
| 4Z9G | Crystal structure of human corticotropin-releasing factor receptor 1 (CRF1R) in complex with the… | x-ray diffraction | A, B, C | OLA, 1Q5, SO4 | 14 (best 0.81) |
| 4Z9G | Crystal structure of human corticotropin-releasing factor receptor 1 (CRF1R) in complex with the… | x-ray diffraction | A, B, C | — | — |
| 6P9X | CRF1 Receptor Gs GPCR protein complex with CRF1 peptide | electron microscopy | R | — | 6 (best 0.75) |
| 6P9X | CRF1 receptor gs GPCR protein complex with CRF1 peptide | electron microscopy | R | — | — |
| 6PB0 | Cryo-EM structure of urocortin 1-bound corticotropin-releasing factor 1 receptor in complex with gs… | electron microscopy | R | CLR, PLM | — |
| P34998 | AlphaFold monomer V2.0 prediction for corticotropin-releasing factor receptor 1 (P34998) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6P9X chain R against the predicted model P34998: TM-score 0.96, RMSD 1.48 Å
- 6P9X chain R against the predicted model P34998: TM-score 0.96, RMSD 1.48 Å
- 6PB0 chain R against the predicted model P34998: TM-score 0.94, RMSD 1.70 Å
- 3EHT chain A against the predicted model P0AEX9: TM-score 0.81, RMSD 0.56 Å
- 3EHS chain A against the predicted model P0AEX9: TM-score 0.81, RMSD 0.58 Å
- 3EHU chain A against the predicted model P0AEX9: TM-score 0.82, RMSD 0.49 Å
- 4K5Y chain C against the predicted model P34998: TM-score 0.81, RMSD 3.13 Å
- 4K5Y chain C against the predicted model P34998: TM-score 0.81, RMSD 3.13 Å
- 2L27 chain A against the predicted model P34998: TM-score 0.78, RMSD 2.04 Å
- 2L27 chain A against the predicted model P34998: TM-score 0.78, RMSD 2.04 Å
Elsewhere
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