UniProt P34736
Transketolase (P34736)
Transketolase (UniProt P34736), EC 2.2.1.1: 49 experimental structures on GenesisL1, 18 ligands bound, 86 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P34736
- Protein
- Transketolase
- EC
- 2.2.1.1
- Experimental structures
- 49
- Predicted models
- 0
- Ligands
- 18
- Pockets
- 86 · 18 records with a druggable one
Structures
49 records of P34736 in the MolNFT archive: 49 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5HGX | Crystal Structure of Transketolase mutant - H261F from Pichia Stipitis | x-ray diffraction | A | — | — |
| 5HGX | Crystal structure of transketolase mutant - H261F from pichia stipitis | x-ray diffraction | A | — | — |
| 5HJE | Crystal Structure of Transketolase complex with sedoheptulose-7-phoaphate from Pichia Stipitis | x-ray diffraction | A | TPP, CA, I22 | — |
| 5HJE | Crystal structure of transketolase complex with sedoheptulose-7- phoaphate from pichia stipitis | x-ray diffraction | A | — | — |
| 5HYV | Crystal Structure of Transketolase with ThDP from Pichia Stipitis | x-ray diffraction | A | TPP, CA | 5 (best 0.55) |
| 5HYV | Crystal structure of transketolase with thdp from pichia stipitis | x-ray diffraction | A | — | — |
| 5I4I | Crystal Structure of Transketolase from Pichia Stipitis | x-ray diffraction | A | — | 4 (best 0.55) |
| 5I4I | Crystal structure of transketolase from pichia stipitis | x-ray diffraction | A | — | — |
| 5I51 | Crystal Structure of Transketolase mutant-R356L complex with fructose-6-phoaphate from Pichia… | x-ray diffraction | A | TPP, F6R, CA | 5 (best 0.64) |
| 5I51 | Crystal structure of transketolase mutant-R356L complex with fructose- 6-phoaphate from pichia… | x-ray diffraction | A | — | — |
| 5I5E | Crystal Structure of Transketolase mutants-H66/261C complex with xylulose-5-phoaphate from Pichia… | x-ray diffraction | A | TPP, 5SP, CA | 5 (best 0.61) |
| 5I5E | Crystal structure of transketolase mutants-H66/261C complex with xylulose-5-phoaphate from pichia… | x-ray diffraction | A | — | — |
| 5I5G | Crystal Structure of Transketolase mutant-R525L from Pichia Stipitis | x-ray diffraction | A | POP | 5 (best 0.63) |
| 5I5G | Crystal structure of transketolase mutant-R525L from pichia stipitis | x-ray diffraction | A | — | — |
| 5XPS | Crystal Structure of Transketolase in complex with erythrose-4-phosphate from Pichia Stipitis | x-ray diffraction | A | TPP, E4P, CA | 5 (best 0.57) |
| 5XPS | Crystal structure of transketolase in complex with erythrose-4- phosphate from pichia stipitis | x-ray diffraction | A | TPP, E4P, CA | — |
| 5XQA | Crystal Structure of Transketolase in complex with ribose-5-phosphate from Pichia Stipitis | x-ray diffraction | A | TPP, CA, HSX | 5 (best 0.60) |
| 5XQA | Crystal structure of transketolase in complex with ribose-5-phosphate from pichia stipitis | x-ray diffraction | A | TPP, CA, HSX | — |
| 5XQK | Crystal Structure of Transketolase in complex with xylulose-5-phosphate from Pichia Stipitis | x-ray diffraction | A | T5X, CA | 6 (best 0.60) |
| 5XQK | Crystal structure of transketolase in complex with xylulose-5- phosphate from pichia stipitis | x-ray diffraction | A | T5X, CA | — |
| 5XRV | Crystal Structure of Transketolase in complex with TPP_V and fructose-6-phosphate from Pichia… | x-ray diffraction | A | CA, F6R, 8EF, TPP | — |
| 5XRV | Crystal structure of transketolase in complex with TPP_V and fructose- 6-phosphate from pichia… | x-ray diffraction | A | CA, F6R, 8EF, TPP | — |
| 5XRY | Crystal Structure of Transketolase contains cysteinesufonic acid from Pichia Stipitis | x-ray diffraction | A | CA | 5 (best 0.59) |
| 5XRY | Crystal structure of transketolase contains cysteinesufonic acid from pichia stipitis | x-ray diffraction | A | CA | — |
| 5XS6 | Crystal Structure of Transketolase in complex with TPP Pichia Stipitis | x-ray diffraction | A | CA, TPP | 5 (best 0.55) |
| 5XS6 | Crystal structure of transketolase in complex with tpp pichia stipitis | x-ray diffraction | A | CA, TPP | — |
| 5XSA | Crystal Structure of Transketolase in complex with TPP intermediate III from Pichia Stipitis | x-ray diffraction | A | CA, 8EL | 4 (best 0.60) |
| 5XSA | Crystal structure of transketolase in complex with tpp intermediate III from pichia stipitis | x-ray diffraction | A | CA, 8EL | — |
| 5XSB | Crystal structure of transketolase in complex with tpp intermediate III from pichia stipitis | x-ray diffraction | A | CA, 8EL | — |
| 5XSM | Crystal Structure of Transketolase in complex with TPP intermediate IV from Pichia Stipitis | x-ray diffraction | A | CA, 8EO | 5 (best 0.60) |
| 5XSM | Crystal structure of transketolase in complex with tpp intermediate IV from pichia stipitis | x-ray diffraction | A | CA, 8EO | — |
| 5XT0 | Crystal Structure of Transketolase in complex with TPP intermediate VIII from Pichia Stipitis | x-ray diffraction | A | CA, T6F | 4 (best 0.56) |
| 5XT0 | Crystal structure of transketolase in complex with tpp intermediate VIII from pichia stipitis | x-ray diffraction | A | CA, T6F | — |
| 5XT4 | Crystal Structure of Transketolase in complex with TPP intermediate VIII' from Pichia Stipitis | x-ray diffraction | A | CA, T6F | 5 (best 0.59) |
| 5XT4 | Crystal structure of transketolase in complex with tpp intermediate VIII' from pichia stipitis | x-ray diffraction | A | CA, T6F | — |
| 5XTL | Crystal Structure of Transketolase in complex with aminopyrimidine and cysteine sulfonic acid… | x-ray diffraction | A | P23, CA, 8GF | 5 (best 0.60) |
| 5XTL | Crystal structure of transketolase in complex with aminopyrimidine and cysteine sulfonic acid… | x-ray diffraction | A | P23, CA, 8GF | — |
| 5XTV | Crystal Structure of Transketolase in complex with TPP intermediate V from Pichia Stipitis | x-ray diffraction | A | CA, 8EF | 5 (best 0.60) |
| 5XTV | Crystal structure of transketolase in complex with tpp intermediate V from pichia stipitis | x-ray diffraction | A | CA, 8EF | — |
| 5XTX | Crystal Structure of Transketolase in complex with TPP intermediate VII from Pichia Stipitis | x-ray diffraction | A | 8ML | — |
| 5XTX | Crystal structure of transketolase in complex with tpp intermediate VII from pichia stipitis | x-ray diffraction | A | 8ML | — |
| 5XU2 | Crystal structure of transketolase in complex with TPP_III and fructose-6-phosphate from pichia… | x-ray diffraction | A | CA, F6R, 8EL, TPP | — |
| 5XU9 | Crystal Structure of Transketolase in complex with TPP intermediate IX and gauche form… | x-ray diffraction | A | CA, 8N9, E4P | — |
| 5XU9 | Crystal structure of transketolase in complex with tpp intermediate IX and gauche form… | x-ray diffraction | A | CA, 8N9, E4P | — |
| 5XUF | Crystal Structure of Transketolase in complex with hydroxylated TPP from Pichia Stipitis, crystal I | x-ray diffraction | A | CA, 8FL | 4 (best 0.60) |
| 5XUF | Crystal structure of transketolase in complex with hydroxylated tpp from pichia stipitis, crystal I | x-ray diffraction | A | CA, 8FL | — |
| 5XVT | Crystal Structure of Transketolase in complex with hydroxylated TPP from Pichia Stipitis, crystal 2 | x-ray diffraction | A | CA, 8FL | 4 (best 0.57) |
| 5XVT | Crystal structure of transketolase in complex with hydroxylated tpp from pichia stipitis, crystal 2 | x-ray diffraction | A | CA, 8FL | — |
| P34736 | AlphaFold monomer V2.0 prediction for transketolase (P34736) | — | — | — |
Ligands
- CA · Calcium ion · in 36 records
- TPP · Thiamine diphosphate · in 13 records
- 8EF · 2-[(5S)-3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methylidene-1,3-thiazolidin-5-yl]ethyl phosphono hydrogen phosphate · in 4 records
- 8EL · 2-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-2H-1,3-thiazol-5-yl]ethyl phosphono hydrogen phosphate · in 4 records
- 8FL · 2-[(2R)-3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-2-oxidanyl-2H-1,3-thiazol-5-yl]ethyl phosphono hydrogen phosphate · in 4 records
- E4P · Erythose-4-phosphate · in 4 records
- F6R · Fructose -6-phosphate · in 4 records
- T6F · 2-C-{3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium-2-yl}-6-O-phosphono-D-glucitol · in 4 records
- 8EO · 2-[(5S)-3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-2,5-dihydro-1,3-thiazol-3-ium-5-yl]ethyl phosphono hydrogen phosphate · in 2 records
- 8GF · 2-methylpyrimidin-4-amine · in 2 records
- 8ML · 2-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methylidene-2-[(2S,3S,4R,5R)-1,2,3,4,5-pentakis(oxidanyl)-6-phosphonooxy-hexan-2-yl]-1,3-thiazolidin-5-yl]ethyl phosphono hydrogen phosphate · in 2 records
- 8N9 · 2-[(2E)-3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-2-[1,2-bis(oxidanyl)ethylidene]-4-methyl-1,3-thiazol-5-yl]ethyl phosphono hydrogen phosphate · in 2 records
- HSX · 5-O-phosphono-alpha-D-ribofuranose · in 2 records
- P23 · Propyl trihydrogen diphosphate · in 2 records
- T5X · 2-C-{3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium-2-yl}-5-O-phosphono-D-xylitol · in 2 records
- 5SP · 5-O-phosphono-D-xylulose · in 1 record
- I22 · D-altro-hept-2-ulose 7-phosphate · in 1 record
- POP · Pyrophosphate 2- · in 1 record
Elsewhere
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