Ligand · HSX
HSX · 5-O-phosphono-alpha-D-ribofuranose
HSX, 5-O-phosphono-alpha-D-ribofuranose (C5 H11 O8 P, 230.1 g/mol), in the MolNFT structures on GenesisL1: bound in 11 records (8 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands…
- Component
- HSX
- Formula
- C5 H11 O8 P
- Class
- ligand
- Structures
- 11
- PDB entries
- 8
Binding sites
HSX in 11 structures; the first of them:
- 5VN4 · Crystal structure of adenine phosphoribosyl transferase from Trypanosoma brucei in… · HSX A302 · binds ARG82, THR118, LYS119, GLU120, TYR121, ASP146, ASP147, VAL148 and 6 more
- 5XQA · Crystal Structure of Transketolase in complex with ribose-5-phosphate from Pichia Stipitis · HSX A703 · binds HIS27, ILE189, HIS261, GLY262
- 7XMU · E.coli phosphoribosylpyrophosphate (PRPP) synthetase type A filament bound with ADP, Pi… · HSX A401 · binds ARG96, HIS131, ASP170, ASP220, ASP221, MET222, ILE223, ASP224 and 4 more
- 8DBE · Human PRPS1 with ADP; Hexamer · HSX A401 · binds ARG96, HIS130, ASP171, ASP220, ASP221, MET222, ALA223, ASP224 and 4 more
- 8DBK · Human PRPS1 with Phosphate, ATP, and R5P; Hexamer with resolved catalytic loops · HSX A402 · binds HIS130, ASP171, ASP220, ASP221, MET222, ALA223, ASP224, THR225 and 3 more
- 8DBN · Human PRPS1-E307A engineered mutation with Phosphate, ATP, and R5P; Hexamer · HSX A402 · binds ARG96, HIS130, ASP171, ASP220, ASP221, MET222, ALA223, ASP224 and 4 more
- 5VN4 · Crystal structure of adenine phosphoribosyl transferase from trypanosoma brucei in… · HSX A302 · binds ARG82, THR118, LYS119, GLU120, TYR121, ASP146, ASP147, VAL148 and 6 more
- 5XQA · Crystal structure of transketolase in complex with ribose-5-phosphate from pichia stipitis · HSX A703 · binds HIS27, ILE189, HIS261, GLY262
- 6NFE · Crystal structure of ribose-phosphate pyrophosphokinase from legionella pneumophila with… · HSX A503 · binds ARG96, HIS131, ASP170, ASP220, ASP221, ILE222, VAL223, ASP224 and 4 more
- 7XMU · E.COLI phosphoribosylpyrophosphate (prpp) synthetase type a filament bound with ADP, pi… · HSX A401 · binds HIS131, ASP170, ASP220, ASP221, MET222, ASP224, THR225, GLY226 and 2 more
- 7XMV · E.COLI phosphoribosylpyrophosphate (prpp) synthetase type A(AMP/ADP) filament bound with… · HSX A401 · binds ASP170, ASP220, ASP221, MET222, ASP224, THR225, GLY226, GLY227 and 1 more
Residues it binds most
ASP 41, THR 41, GLY 43, HIS 33, MET 35, ARG 27, ALA 23, CYS 17, ILE 14, VAL 6 (residue and the binding sites it lines).
Found with
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