UniProt P32641
Checkpoint protein RAD24 (P32641)
Checkpoint protein RAD24 (UniProt P32641): 11 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 60 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P32641
- Protein
- Checkpoint protein RAD24
- Experimental structures
- 11
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 60 · 7 records with a druggable one
Structures
12 records of P32641 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7SGZ | Structure of the yeast Rad24-RFC loader bound to DNA and the closed 9-1-1 clamp | electron microscopy | A | AGS, MG, ADP, PO4 | 9 (best 0.83) |
| 7SGZ | Structure of the yeast RAD24-rfc loader bound to DNA and the closed 9- 1-1 clamp | electron microscopy | A | AGS, MG, ADP | — |
| 7SH2 | Structure of the yeast RAD24-rfc loader bound to DNA and the open 9-1- 1 clamp | electron microscopy | A | AGS, MG, ADP | — |
| 7ST9 | Open state of RAD24-RFC:9-1-1 bound to a 5' SS/DSDNA junction | electron microscopy | A | AGS, MG | — |
| 7STB | Closed state of Rad24-RFC:9-1-1 bound to a 5' ss/dsDNA junction | electron microscopy | A | AGS, MG | 8 (best 0.83) |
| 7STB | Closed state of RAD24-RFC:9-1-1 bound to a 5' SS/DSDNA junction | electron microscopy | A | AGS, MG | — |
| 7STE | RAD24-rfc ADP state | electron microscopy | A | ATP, MG | — |
| 8FS4 | Structure of S. cerevisiae Rad24-RFC loading the 9-1-1 clamp onto a 10-nt gapped DNA in step 2… | electron microscopy | A | AGS, MG | 8 (best 0.86) |
| 8FS6 | Structure of S. cerevisiae Rad24-RFC loading the 9-1-1 clamp onto a 10-nt gapped DNA in step 4… | electron microscopy | A | AGS, MG | 9 (best 0.82) |
| 8FS7 | Structure of S. cerevisiae Rad24-RFC loading the 9-1-1 clamp onto a 10-nt gapped DNA in step 5… | electron microscopy | A | MG, AGS | 9 (best 0.86) |
| 8FS8 | Structure of S. cerevisiae Rad24-RFC loading the 9-1-1 clamp onto a 5-nt gapped DNA (9-1-1… | electron microscopy | A | AGS, MG, ADP | 8 (best 0.86) |
| P32641 | AlphaFold monomer V2.0 prediction for checkpoint protein RAD24 (P32641) | predicted | A | — | 9 (best 0.79) |
Ligands
Experiment against prediction
- 7SH2 chain A against the predicted model P32641: TM-score 0.85, RMSD 3.44 Å
- 7SGZ chain A against the predicted model P32641: TM-score 0.84, RMSD 3.48 Å
- 7SGZ chain A against the predicted model P32641: TM-score 0.84, RMSD 3.48 Å
- 8FS6 chain A against the predicted model P32641: TM-score 0.83, RMSD 3.85 Å
- 8FS8 chain A against the predicted model P32641: TM-score 0.83, RMSD 3.55 Å
- 8FS4 chain A against the predicted model P32641: TM-score 0.83, RMSD 3.93 Å
- 8FS7 chain A against the predicted model P32641: TM-score 0.81, RMSD 4.11 Å
- 7ST9 chain A against the predicted model P32641: TM-score 0.76, RMSD 4.58 Å
- 7STB chain A against the predicted model P32641: TM-score 0.72, RMSD 5.09 Å
- 7STB chain A against the predicted model P32641: TM-score 0.72, RMSD 5.09 Å
Elsewhere
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