UniProt P31422
Metabotropic glutamate receptor 3 (P31422)
Metabotropic glutamate receptor 3 (UniProt P31422): 11 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P31422
- Protein
- Metabotropic glutamate receptor 3
- Experimental structures
- 11
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 8 · 1 record with a druggable one
Structures
12 records of P31422 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2E4U | Crystal structure of the extracellular region of the group II metabotropic glutamate receptor… | x-ray diffraction | A, B | — | — |
| 2E4U | Crystal structure of the extracellular region of the group II metabotropic glutamate receptor… | x-ray diffraction | A, B | — | — |
| 2E4V | Crystal structure of the extracellular region of the group II metabotropic glutamate receptor… | x-ray diffraction | A, B | — | — |
| 2E4V | Crystal structure of the extracellular region of the group II metabotropic glutamate receptor… | x-ray diffraction | A, B | — | — |
| 2E4W | Crystal structure of the extracellular region of the group II metabotropic glutamate receptor… | x-ray diffraction | A, B | — | — |
| 2E4W | Crystal structure of the extracellular region of the group II metabotropic glutamate receptor… | x-ray diffraction | A, B | — | — |
| 2E4X | Crystal structure of the extracellular region of the group II metabotropic glutamate receptor… | x-ray diffraction | A, B | — | — |
| 2E4X | Crystal structure of the extracellular region of the group II metabotropic glutamate receptor… | x-ray diffraction | A, B | — | — |
| 2E4Y | Crystal structure of the extracellular region of the group II metabotropic glutamate receptor… | x-ray diffraction | A, B | — | — |
| 2E4Y | Crystal structure of the extracellular region of the group II metabotropic glutamate receptor… | x-ray diffraction | A, B | — | — |
| 8TR0 | Metabotropic glutamate receptor 3 class 3 bound to antagonist LY 341495 | electron microscopy | A, B | Z99 | 8 (best 0.62) |
| P31422 | AlphaFold monomer V2.0 prediction for metabotropic glutamate receptor 3 (P31422) | predicted | A | — | — |
Ligands
- Z99 · 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine · in 1 record
Experiment against prediction
- 2E4Y chain B against the predicted model P31422: TM-score 0.98, RMSD 1.12 Å
- 2E4Y chain B against the predicted model P31422: TM-score 0.98, RMSD 1.12 Å
- 2E4Y chain A against the predicted model P31422: TM-score 0.96, RMSD 1.76 Å
- 2E4Y chain A against the predicted model P31422: TM-score 0.96, RMSD 1.76 Å
- 2E4U chain A against the predicted model P31422: TM-score 0.94, RMSD 2.12 Å
- 2E4U chain A against the predicted model P31422: TM-score 0.94, RMSD 2.12 Å
- 2E4V chain A against the predicted model P31422: TM-score 0.94, RMSD 2.21 Å
- 2E4V chain A against the predicted model P31422: TM-score 0.94, RMSD 2.21 Å
- 2E4W chain A against the predicted model P31422: TM-score 0.94, RMSD 2.23 Å
- 2E4W chain A against the predicted model P31422: TM-score 0.94, RMSD 2.23 Å
Elsewhere
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