UniProt P28720
Queuine tRNA-ribosyltransferase (P28720)
Queuine tRNA-ribosyltransferase (UniProt P28720), EC 2.4.2.29: 337 experimental structures on GenesisL1, 45 ligands bound, 102 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P28720
- Protein
- Queuine tRNA-ribosyltransferase
- EC
- 2.4.2.29
- Experimental structures
- 337
- Predicted models
- 0
- Ligands
- 45
- Pockets
- 102 · 46 records with a druggable one
Structures
337 records of P28720 in the MolNFT archive: 337 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1EFZ | Mutagenesis and crystallographic studies of zymomonas mobilis tRNA-guanine transglycosylase to… | x-ray diffraction | A | — | — |
| 1EFZ | Mutagenesis and crystallographic studies of zymomonas mobilis tRNA- guanine transglycosylase to… | x-ray diffraction | A | — | — |
| 1ENU | A new target for shigellosis: Rational design and crystallographic studies of inhibitors of… | x-ray diffraction | A | — | — |
| 1ENU | A new target for shigellosis: rational design and crystallographic studies of inhibitors of… | x-ray diffraction | A | — | — |
| 1F3E | A new target for shigellosis: rational design and crystallographic studies of inhibitors of… | x-ray diffraction | A | — | — |
| 1F3E | A new target for shigellosis: rational design and crystallographic studies of inhibitors of… | x-ray diffraction | A | — | — |
| 1K4G | Crystal structure of tRNA-guanine transglycosylase (tgt) complexed with… | x-ray diffraction | A | — | — |
| 1K4G | Crystal structure of tRNA-guanine transglycosylase (tgt) complexed with… | x-ray diffraction | A | — | — |
| 1K4H | CRYSTAL STRUCTURE OF TRNA-GUANINE TRANSGLYCOSYLASE (TGT) COMPLEXED WITH… | x-ray diffraction | A | — | — |
| 1K4H | Crystal structure of tRNA-guanine transglycosylase (tgt) complexed with… | x-ray diffraction | A | — | — |
| 1N2V | Crystal Structure of TGT in complex with 2-Butyl-5,6-dihydro-1H-imidazo[4,5-d]pyridazine-4,7-dione | x-ray diffraction | A | — | — |
| 1N2V | Crystal structure of tgt in complex with 2-butyl-5,6-dihydro-1H- IMIDAZO[4,5-D]PYRIDAZINE-4,7-dione | x-ray diffraction | A | — | — |
| 1OZM | Y106F mutant of Z. mobilis TGT | x-ray diffraction | A | — | — |
| 1OZM | Y106F mutant of Z. mobilis tgt | x-ray diffraction | A | — | — |
| 1OZQ | Crystal structure of the mutated tRNA-guanine transglycosylase (TGT)Y106F complexed with PREQ1 | x-ray diffraction | A | — | — |
| 1OZQ | Crystal structure of the mutated tRNA-guanine transglycosylase (tgt) Y106F complexed with PREQ1 | x-ray diffraction | A | — | — |
| 1P0B | Crystal Structure Of tRNA-Guanine Transglycosylase (TGT) From Zymomonas mobilis Complexed With… | x-ray diffraction | A | — | — |
| 1P0B | Crystal structure of tRNA-guanine transglycosylase (tgt) from zymomonas mobilis complexed with… | x-ray diffraction | A | — | — |
| 1P0D | CRYSTAL STRUCTURE OF ZYMOMONAS MOBILIS tRNA-GUANINE TRANSGLYCOSYLASE (TGT) CRYSTALLISED AT PH 5.5 | x-ray diffraction | A | — | — |
| 1P0D | Crystal structure of zymomonas mobilis tRNA-guanine transglycosylase (tgt) crystallised at pH 5.5 | x-ray diffraction | A | — | — |
| 1P0E | CRYSTAL STRUCTURE OF ZYMOMONAS MOBILIS tRNA-GUANINE TRANSGLYCOSYLASE (TGT) COCRYSTALLISED WITH… | x-ray diffraction | A | — | — |
| 1P0E | Crystal structure of zymomonas mobilis tRNA-guanine transglycosylase (tgt) cocrystallised with… | x-ray diffraction | A | — | — |
| 1PUD | TRNA-guanine transglycosylase | x-ray diffraction | A | — | — |
| 1PUD | TRNA-guanine transglycosylase | x-ray diffraction | A | — | — |
| 1PXG | Crystal structure of the mutated tRNA-guanine transglycosylase (TGT) D280E complexed with preQ1 | x-ray diffraction | A | — | — |
| 1PXG | Crystal structure of the mutated tRNA-guanine transglycosylase (tgt) D280E complexed with PREQ1 | x-ray diffraction | A | — | — |
| 1Q2R | Chemical trapping and crystal structure of a catalytic tRNA guanine transglycosylase covalent… | x-ray diffraction | A, B, C, D | — | — |
| 1Q2R | Chemical trapping and crystal structure of a catalytic tRNA guanine transglycosylase covalent… | x-ray diffraction | A, B, C, D | — | — |
| 1Q2S | Chemical trapping and crystal structure of a catalytic tRNA guanine transglycosylase covalent… | x-ray diffraction | A, B, C, D | — | — |
| 1Q2S | Chemical trapping and crystal structure of a catalytic tRNA guanine transglycosylase covalent… | x-ray diffraction | A, B, C, D | — | — |
| 1Q4W | Crystal structure of tgt in complex with 2,6-diamino-3H-quinazolin-4-one | x-ray diffraction | A | — | — |
| 1Q4W | Crystal structure of tgt in complex with 2,6-diamino-3H-quinazolin-4- one | x-ray diffraction | A | — | — |
| 1Q63 | CRYSTAL STRUCTURE OF TGT IN COMPLEX WITH 2,6-Diamino-8-(1H-imidazol-2-ylsulfanylmethyl)-3H-quinazoli… | x-ray diffraction | A | — | — |
| 1Q63 | Crystal structure of tgt in complex with 2,6-diamino-8-(1H-imidazol-2… | x-ray diffraction | A | — | — |
| 1Q65 | CRYSTAL STRUCTURE OF TGT IN COMPLEX WITH 2,6-DIAMINO-8-(2-dimethylaminoethylsulfanylmethyl)-3H-QUINA… | x-ray diffraction | A | — | — |
| 1Q65 | Crystal structure of tgt in complex with 2,6-diamino-8-(2… | x-ray diffraction | A | — | — |
| 1Q66 | CRYSTAL STRUCTURE OF TGT IN COMPLEX WITH 2-AMINO-6-AMINOMETHYL-8-phenylsulfanylmethyl-3H-QUINAZOLIN… | x-ray diffraction | A | — | — |
| 1Q66 | Crystal structure of tgt in complex with 2-amino-6-aminomethyl-8… | x-ray diffraction | A | — | — |
| 1R5Y | Crystal Structure of TGT in complex with 2,6-Diamino-3H-Quinazolin-4-one Crystallized at PH 5.5 | x-ray diffraction | A | — | — |
| 1R5Y | Crystal structure of tgt in complex with 2,6-diamino-3H-quinazolin-4- one crystallized at pH 5.5 | x-ray diffraction | A | — | — |
| 1S38 | Crystal structure of tgt in complex with 2-amino-8-methylquinazolin-4(3H)-one | x-ray diffraction | A | — | — |
| 1S38 | Crystal structure of tgt in complex with 2-amino-8-methylquinazolin- 4(3H)-one | x-ray diffraction | A | — | — |
| 1S39 | CRYSTAL STRUCTURE OF TGT IN COMPLEX WITH 2-aminoquinazolin-4(3H)-one | x-ray diffraction | A | — | — |
| 1S39 | Crystal structure of tgt in complex with 2-aminoquinazolin-4(3H)-one | x-ray diffraction | A | — | — |
| 1WKD | TRNA-guanine transglycosylase | x-ray diffraction | A | — | — |
| 1WKD | TRNA-guanine transglycosylase | x-ray diffraction | A | — | — |
| 1WKE | TRNA-guanine transglycosylase | x-ray diffraction | A | — | — |
| 1WKE | TRNA-guanine transglycosylase | x-ray diffraction | A | — | — |
| 1WKF | TRNA-guanine transglycosylase | x-ray diffraction | A | — | — |
| 1WKF | TRNA-guanine transglycosylase | x-ray diffraction | A | — | — |
| 1Y5V | tRNA-Guanine Transglycosylase (TGT) in complex with… | x-ray diffraction | A | — | — |
| 1Y5V | TRNA-guanine transglycosylase (tgt) in complex with 6-amino-4-(2… | x-ray diffraction | A | — | — |
| 1Y5W | tRNA-guanine Transglycosylase (TGT) in complex with… | x-ray diffraction | A | — | — |
| 1Y5W | TRNA-guanine transglycosylase (tgt) in complex with 6-amino-4-[2-(4… | x-ray diffraction | A | — | — |
| 1Y5X | tRNA-guanine Transglycosylase (TGT) in complex with… | x-ray diffraction | A, D | — | — |
| 1Y5X | TRNA-guanine transglycosylase (tgt) in complex with 6-amino-4-[2-(4… | x-ray diffraction | A, D | — | — |
| 2NQZ | Trna-guanine transglycosylase (TGT) mutant in complex with 7-deaza-7-aminomethyl-guanine | x-ray diffraction | A | — | — |
| 2NQZ | TRNA-guanine transglycosylase (tgt) mutant in complex with 7-deaza-7- aminomethyl-guanine | x-ray diffraction | A | — | — |
| 2NSO | Trna-gunanine-transglycosylase (TGT) mutant Y106F, C158V, A232S, V233G- APO-Structure | x-ray diffraction | A | — | — |
| 2NSO | TRNA-gunanine-transglycosylase (tgt) mutant Y106F, C158V, A232S, V233G- apo-structure | x-ray diffraction | A | — | — |
277 records more on the page itself.
Ligands
- ZN · Zinc ion · in 111 records
- CL · Chloride ion · in 29 records
- 726 · 6-azanyl-2-(methylamino)-4-[2-[(2~{R},3~{R},4~{S}, 5~{R},6~{S})-3,4,5,6-tetramethoxyoxan-2-yl]ethyl]-1,7-dihydroimidazo[4,5-g]quinazolin-8-one · in 6 records
- 72C · 4-[2-[(3~{A}~{R},4~{R},6~{R},6~{A}~{R})-4-methoxy-2,2-dimethyl-3~{A},4,6,6~{A}-tetrahydrofuro[3,4-D][1, 3]dioxol-6-yl]ethyl]-6-azanyl-2-(methylamino)-1,7-dihydroimidazo[4,5-g]quinazolin-8-one · in 5 records
- NE8 · 6-amino-4-(2-phenylethyl)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one · in 5 records
- 725 · 6-amino-2-(methylamino)-4-(2-((2R,3R,4R,5R)-3,4,5-trimethoxytetrahydrofuran-2-yl)ethyl)-1H-imidazo[4,5-g]quinazolin-8(7H)-one · in 4 records
- OQN · 6-amino-2-(methylamino)-4-phenethyl-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one · in 4 records
- NEZ · 6-amino-4-[2-(4-methylphenyl)ethyl]-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one · in 3 records
- OQQ · 6-amino-2-(methylamino)-4-(4-(trifluoromethyl) phenethyl)-3,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one · in 3 records
- 46L · 6-(dimethylamino)pyridine-3-carboxylic acid · in 2 records
- 6MM · 6-amino-2-({[(3a'R,4S,6'R,6a'R)-2,2,2',2'-tetramethyldihydro-3a'H-spiro[1,3-dioxolane-4,4'-furo[3,4-d][1,3]dioxol]-6'-yl]methyl}amino)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one (non-preferred name) · in 2 records
- 6MQ · methyl 5-[(6-amino-8-oxo-7,8-dihydro-3H-imidazo[4,5-g]quinazolin-2-yl)amino]-5-deoxy-2,3-O-(1-methylethylidene)-beta-D-ribofuranoside · in 2 records
- 6NK · 2-{[2-(morpholin-4-yl)ethyl]amino}-1H-benzimidazole-6-carboxamide · in 2 records
- AMH · Trans-4-aminomethylcyclohexane-1-carboxylic acid · in 2 records
- AZA · 8-azaxanthine · in 2 records
- E48 · 6-azanyl-2-[[(1~{R},2~{S},6~{S},9~{R})-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.0^{2, 6}]dodecan-6-yl]methylamino]-3,7-dihydroimidazo[4,5-g]quinazolin-8-one · in 2 records
- E4E · 6-azanyl-2-[[(2~{R},3~{S},4~{R},5~{R})-5-methoxy-3,4-bis(oxidanyl)oxolan-2-yl]methylamino]-3,7-dihydroimidazo[4,5-g]quinazolin-8-one · in 2 records
- F63 · N-methyl-1-[5-(pyridin-3-yloxy)furan-2-yl]methanamine · in 2 records
- GUN · Guanine · in 2 records
- ITE · 2-(methylamino)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one · in 2 records
- K75 · (8~{R})-~{N}2-methyl-8-prop-1-ynyl-7,8-dihydro-3~{H}-imidazo[4,5-g]quinazoline-2,6-diamine · in 2 records
- K7H · ~{N}2-methyl-7,8-dihydro-3~{H}-imidazo[4,5-g]quinazoline-2,6-diamine · in 2 records
- OQH · ~{N}-ethyl-4-oxidanylidene-4-phenyl-butanamide · in 2 records
- QXB · sulfolane · in 2 records
- QXE · 3-hydroxythietane-1,1-dioxide · in 2 records
- QZT · thiolane 1-oxide · in 2 records
- R1E · trans-4,4-difluorocyclopentane-1,2-diol · in 2 records
- R4W · 1-methylsulfonylethane · in 2 records
- RGN · (1~{R},2~{R})-4,4-bis(fluoranyl)cyclopentane-1,2-diol · in 2 records
- 1UD · methyl 6-[6-amino-2-(methylamino)-8-oxo-7,8-dihydro-1H-imidazo[4,5-g]quinazolin-4-yl]-5,6-dideoxy-3-O-methyl-beta-D-ribo-hexofuranoside · in 1 record
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.