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Ligand · ITE

ITE · 2-(methylamino)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one

ITE, 2-(methylamino)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one (C10 H9 N5 O, 215.2 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it…

Component
ITE
Formula
C10 H9 N5 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

ITE in 2 structures; the first of them:

  • 6YH2 · tRNA-guanine Transglycosylase (TGT) labeled with 5-fluorotryptophan in co-crystallized… · ITE A404 · binds TYR106, ASP156, CYS158, ILE201, GLN203, GLY229, GLY230, LEU231 and 4 more
  • 6YH2 · TRNA-guanine transglycosylase (tgt) labeled with 5-fluorotryptophan in co-crystallized… · ITE A404 · binds TYR106, ASP156, CYS158, GLN203, GLY229, GLY230, LEU231, ALA232 and 3 more

Residues it binds most

GLY 2, ALA 2, ASP 2, CYS 2, GLN 2, LEU 2, MET 2, TYR 2, VAL 2, ILE 1 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion
  • CL · Chloride ion
  • GOL · Glycerol

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