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Ligand · CKR

CKR · 6-amino-2-[(2-morpholin-4-ylethyl)amino]-3,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one

CKR, 6-amino-2-[(2-morpholin-4-ylethyl)amino]-3,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one (C15 H19 N7 O2, 329.4 g/mol), in the MolNFT structures on GenesisL1: bound in 8 records (4 PDB entries). Every binding site with its residues…

Component
CKR
Formula
C15 H19 N7 O2
Class
ligand
Structures
8
PDB entries
4

Binding sites

CKR in 8 structures; the first of them:

  • 4PUJ · tRNA-Guanine Transglycosylase (TGT) in Complex with… · CKR A407 · binds ASP102, SER103, GLY105, TYR106, ASP156, CYS158, ILE201, GLN203 and 9 more
  • 4Q8O · tRNA-Guanine Transglycosylase (TGT) Mutant V262T in Complex with… · CKR A406 · binds ASP102, SER103, GLY105, TYR106, ASP156, CYS158, ILE201, GLN203 and 9 more
  • 4Q8P · tRNA-Guanine Transglycosylase (TGT) Mutant V262D in Complex with… · CKR A405 · binds ASP102, SER103, TYR106, ASP156, CYS158, ILE201, GLN203, GLY229 and 8 more
  • 4Q8Q · tRNA-Guanine Transglycosylase (TGT) Mutant V262C in Complex with… · CKR A402 · binds ASP102, SER103, GLY105, TYR106, ASP156, CYS158, ILE201, GLN203 and 8 more
  • 4PUJ · TRNA-guanine transglycosylase (tgt) in complex with 6-amino-2-{[2… · CKR A407 · binds ASP102, SER103, GLY105, TYR106, ASP156, CYS158, ILE201, GLN203 and 9 more
  • 4Q8O · TRNA-guanine transglycosylase (tgt) mutant V262T in complex with 6… · CKR A406 · binds ASP102, SER103, GLY105, TYR106, ASP156, CYS158, ILE201, GLN203 and 9 more
  • 4Q8P · TRNA-guanine transglycosylase (tgt) mutant V262D in complex with 6… · CKR A405 · binds ASP102, SER103, TYR106, ASP156, CYS158, ILE201, GLN203, GLY229 and 8 more
  • 4Q8Q · TRNA-guanine transglycosylase (tgt) mutant V262C in complex with 6… · CKR A402 · binds ASP102, SER103, GLY105, TYR106, ASP156, CYS158, ILE201, GLN203 and 8 more

Residues it binds most

GLY 8, ASP 8, VAL 8, CYS 8, ALA 8, GLN 8, ILE 8, LEU 8, MET 8, SER 8 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion
  • GOL · Glycerol
  • CL · Chloride ion

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