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Ligand · PK2

PK2 · 6-amino-4-{2-[(cyclohexylmethyl)amino]ethyl}-2-(methylamino)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one

PK2, 6-amino-4-{2-[(cyclohexylmethyl)amino]ethyl}-2-(methylamino)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one (C19 H27 N7 O, 369.5 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with…

Component
PK2
Formula
C19 H27 N7 O
Class
ligand
Structures
4
PDB entries
2

Binding sites

PK2 in 4 structures; the first of them:

  • 3EOS · tRNA-guanine transglycosylase in complex with 6-amino-4-{2-[(cyclohexylmethyl)amino]ethyl}… · PK2 A400 · binds VAL45, GLY46, LEU68, GLY69, ASN70, ASP102, SER103, TYR106 and 15 more
  • 5I02 · tRNA guanine transglycosylase (TGT) in co-crystallized complex with… · PK2 A402 · binds VAL45, LEU68, GLY69, ASN70, ASP102, SER103, TYR106, GLN107 and 13 more
  • 3EOS · TRNA-guanine transglycosylase in complex with 6-amino-4-{2… · PK2 A400 · binds VAL45, GLY46, LEU68, GLY69, ASN70, ASP102, SER103, TYR106 and 15 more
  • 5I02 · TRNA guanine transglycosylase (tgt) in co-crystallized complex with 6… · PK2 A402 · binds VAL45, LEU68, GLY69, ASN70, ASP102, SER103, TYR106, GLN107 and 13 more

Residues it binds most

GLY 4, ASP 4, VAL 4, GLN 4, LEU 4, TYR 4, ALA 4, ASN 4, CYS 4, ILE 4 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion
  • GOL · Glycerol
  • CL · Chloride ion
  • EDO · 1,2-ethanediol

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