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UniProt P19388

DNA-directed RNA polymerases I, II, and III subunit RPABC1 (P19388)

DNA-directed RNA polymerases I, II, and III subunit RPABC1 (UniProt P19388): 37 experimental structures and 1 predicted model on GenesisL1, 21 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…

UniProt
P19388
Protein
DNA-directed RNA polymerases I, II, and III subunit RPABC1
Experimental structures
37
Predicted models
1
Pockets
21 · 7 records with a druggable one

Structures

38 records of P19388 in the MolNFT archive: 37 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
5IY6Human holo-PIC in the closed stateelectron microscopyE—4 (best 0.88)
5IY6Human holo-pic in the closed stateelectron microscopyE——
5IY7Human holo-pic in the open stateelectron microscopyE——
5IY8Human holo-pic in the initial transcribing stateelectron microscopyE——
5IY9Human holo-PIC in the initial transcribing state (no IIS)electron microscopyE——
5IY9Human holo-pic in the initial transcribing state (no iis)electron microscopyE——
5IYAHuman core-PIC in the closed stateelectron microscopyE——
5IYAHuman core-pic in the closed stateelectron microscopyE——
5IYBHuman core-pic in the open stateelectron microscopyE——
5IYCHuman core-PIC in the initial transcribing stateelectron microscopyE—3 (best 0.83)
5IYCHuman core-pic in the initial transcribing stateelectron microscopyE——
5IYDHuman core-PIC in the initial transcribing state (no IIS)electron microscopyE——
5IYDHuman core-pic in the initial transcribing state (no iis)electron microscopyE——
6DRDRNA pol II(G)electron microscopyE——
6O9LHuman holo-pic in the closed stateelectron microscopyE——
6XREStructure of the P53/RNA polymerase II assemblyelectron microscopyE——
7A6HCryo-EM structure of human apo RNA polymerase IIIelectron microscopyE——
7AE1Cryo-EM structure of human RNA Polymerase III elongation complex 1electron microscopyE—3 (best 0.80)
7AE1Cryo-EM structure of human RNA polymerase III elongation complex 1electron microscopyE——
7AE3Cryo-EM structure of human RNA polymerase III elongation complex 3electron microscopyE——
7AEACryo-EM structure of human RNA Polymerase III elongation complex 2electron microscopyE—3 (best 0.81)
7AEACryo-EM structure of human RNA polymerase III elongation complex 2electron microscopyE——
7ASTApo human RNA polymerase IIIelectron microscopyF——
7D58Cryo-EM structure of human RNA polymerase III in elongating stateelectron microscopyE——
7D59Cryo-EM structure of human RNA polymerase III in apo stateelectron microscopyE——
7DN3Structure of human RNA polymerase III elongation complexelectron microscopyE——
7DU2RNA polymerase III ec complex in post-translocation stateelectron microscopyE——
7FJIhuman Pol III elongation complexelectron microscopyE—2 (best 0.80)
7FJIHuman pol III elongation complexelectron microscopyE——
7FJJHuman pol III pre-termination complexelectron microscopyE——
7OB9Cryo-EM structure of human RNA polymerase I in elongation stateelectron microscopyE——
7OBACryo-EM structure of human RNA polymerase I in complex with RRN3electron microscopyE——
7OBBCryo-EM structure of human RNA polymerase I open complexelectron microscopyE——
7VBAStructure of the pre state human RNA Polymerase I Elongation Complexelectron microscopyE——
8A43Human RNA polymerase Ielectron microscopyE—3 (best 0.75)
8A43Human RNA polymerase Ielectron microscopyE——
8IUERNA polymerase III pre-initiation complex melting complex 1electron microscopyE—1 (best 0.84)
P19388AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerases I, II, and III subunit RPABC1…predictedA—2 (best 0.47)

Experiment against prediction

Elsewhere

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