UniProt P17870
Beta-arrestin-1 (P17870)
Beta-arrestin-1 (UniProt P17870): 25 experimental structures and 1 predicted model on GenesisL1, 44 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P17870
- Protein
- Beta-arrestin-1
- Experimental structures
- 25
- Predicted models
- 1
- Pockets
- 44 · 6 records with a druggable one
Structures
26 records of P17870 in the MolNFT archive: 25 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1G4M | Crystal structure of bovine beta-arrestin 1 | x-ray diffraction | A, B | — | — |
| 1G4M | Crystal structure of bovine beta-arrestin 1 | x-ray diffraction | A, B | — | — |
| 1G4R | Crystal structure of bovine beta-arrestin 1 | x-ray diffraction | A | — | — |
| 1G4R | Crystal structure of bovine beta-arrestin 1 | x-ray diffraction | A | — | — |
| 1JSY | Crystal structure of bovine arrestin-2 | x-ray diffraction | A | — | — |
| 1JSY | Crystal structure of bovine arrestin-2 | x-ray diffraction | A | — | — |
| 1ZSH | Crystal structure of bovine arrestin-2 in complex with inositol hexakisphosphate (IP6) | x-ray diffraction | A | — | — |
| 1ZSH | Crystal structure of bovine arrestin-2 in complex with inositol hexakisphosphate (IP6) | x-ray diffraction | A | — | — |
| 2WTR | Full length Arrestin2 | x-ray diffraction | A, B | — | — |
| 2WTR | Full length ARRESTIN2 | x-ray diffraction | A, B | — | — |
| 3GC3 | Crystal Structure of Arrestin2S and Clathrin | x-ray diffraction | A | — | — |
| 3GC3 | Crystal structure of ARRESTIN2S and clathrin | x-ray diffraction | A | — | — |
| 3GD1 | Structure of an Arrestin/Clathrin complex reveals a novel clathrin binding domain that modulates… | x-ray diffraction | C, E | — | — |
| 3GD1 | Structure of an ARRESTIN/CLATHRIN complex reveals a novel clathrin binding domain that modulates… | x-ray diffraction | C, E | — | — |
| 6NI2 | Stabilized beta-arrestin 1-V2T subcomplex of a GPCR-G protein-beta-arrestin mega-complex | electron microscopy | B | — | 8 (best 0.80) |
| 6NI2 | Stabilized beta-arrestin 1-V2T subcomplex of a GPCR-G protein-beta- arrestin mega-complex | electron microscopy | B | — | — |
| 7DF9 | Crystal of Arrestin2-V2Rpp-1-Fab30 complex | x-ray diffraction | A | — | 7 (best 0.80) |
| 7DF9 | Crystal of ARRESTIN2-V2RPP-1-FAB30 complex | x-ray diffraction | A | — | — |
| 7DFA | Crystal of ARRESTIN2-V2RPP-4-FAB30 complex | x-ray diffraction | A | — | — |
| 7DFB | Crystal of Arrestin2-V2Rpp-6-7-Fab30 complex | x-ray diffraction | A | — | 11 (best 0.79) |
| 7DFB | Crystal of ARRESTIN2-V2RPP-6-7-FAB30 complex | x-ray diffraction | A | — | — |
| 7DFC | Crystal of Arrestin2-V2Rpp-3-Fab30 complex | x-ray diffraction | A | — | 8 (best 0.81) |
| 7DFC | Crystal of ARRESTIN2-V2RPP-3-FAB30 complex | x-ray diffraction | A | — | — |
| 8J97 | Structure of Muscarinic receptor (M2R) in complex with beta-arrestin1 (Local refine, cross-linked) | electron microscopy | A | — | 4 (best 0.66) |
| 8JAF | Structure of Muscarinic receptor (M2R) in complex with beta-arrestin1 (Local Refine, non-cross… | electron microscopy | A | — | 6 (best 0.73) |
| P17870 | AlphaFold monomer V2.0 prediction for beta-arrestin-1 (P17870) | predicted | A | — | — |
Experiment against prediction
- 3GD1 chain C against the predicted model P17870: TM-score 0.98, RMSD 1.05 Å
- 3GD1 chain C against the predicted model P17870: TM-score 0.98, RMSD 1.05 Å
- 2WTR chain A against the predicted model P17870: TM-score 0.97, RMSD 1.44 Å
- 2WTR chain A against the predicted model P17870: TM-score 0.97, RMSD 1.44 Å
- 1G4M chain A against the predicted model P17870: TM-score 0.97, RMSD 1.40 Å
- 1G4M chain A against the predicted model P17870: TM-score 0.97, RMSD 1.40 Å
- 3GD1 chain E against the predicted model P17870: TM-score 0.97, RMSD 1.23 Å
- 3GD1 chain E against the predicted model P17870: TM-score 0.97, RMSD 1.23 Å
- 1G4M chain B against the predicted model P17870: TM-score 0.97, RMSD 1.35 Å
- 1G4M chain B against the predicted model P17870: TM-score 0.97, RMSD 1.35 Å
Elsewhere
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