MolNFT v1 · #7369 · protein
Crystal structure of bovine beta-arrestin 1
1G4M · Beta-ARRESTIN1: “Crystal structure of bovine beta-arrestin 1”. X-ray diffraction, 5 pockets (best druggability 0.62). MolNFT v1 #7369 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1G4M
- Type
- protein
- Length
- 713 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Beta-ARRESTIN1
- UniProt
- P17870
- Pockets
- 5 · best druggability 0.62
Structure
x-ray diffraction · 2 distinct chains · 6% helix, 49% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Beta-ARRESTIN1 | protein | 356 | 8% helix, 49% strand | P17870 |
| B | Beta-ARRESTIN1 | protein | 357 | 5% helix, 50% strand | P17870 |
Pockets
5 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 80 | 0.62 | 0.90 | 27 | empty |
| 2 | 65 | 0.60 | 0.91 | 23 | empty |
| 3 | 288 | 0.56 | 0.77 | 34 | empty |
| 4 | 258 | 0.55 | 0.77 | 39 | empty |
| 5 | 79 | 0.35 | 0.76 | 21 | empty |
Interfaces
1 interface between chains.
- A–B · 747 Ų buried · 19 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P17870
- Elsewhere: RCSB PDB 1G4M · PDBe 1G4M · UniProt P17870
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