MolNFT v1 · #11649 · protein

Crystal structure of bovine arrestin-2

1JSY · Bovine arrestin-2 (full length): “Crystal structure of bovine arrestin-2”. X-ray diffraction, 4 pockets (best druggability 0.64). MolNFT v1 #11649 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1JSY
Type: protein
Length: 358 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Bovine arrestin-2 (full length)
UniProt: P17870
Pockets: 4 · best druggability 0.64

Structure

x-ray diffraction · 1 distinct chain · 4% helix, 47% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Bovine arrestin-2 (full length)	protein	358	4% helix, 47% strand	P17870

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	133	0.64	0.87	31	empty
2	153	0.58	0.83	28	empty
3	82	0.40	0.78	14	empty
4	65	0.27	0.73	15	empty

Compared structures

1JSY · Crystal structure of bovine arrestin-2 · the same entry in another collection · chain A against A, TM-score 1.00
P17870 · AlphaFold monomer V2.0 prediction for beta-arrestin-1 (P17870) · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P17870
Elsewhere: RCSB PDB 1JSY · PDBe 1JSY · UniProt P17870

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