UniProt P16581
E-selectin (P16581)
E-selectin (UniProt P16581): 13 experimental structures on GenesisL1, 6 ligands bound. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P16581
- Protein
- E-selectin
- Experimental structures
- 13
- Predicted models
- 0
- Ligands
- 6
Structures
13 records of P16581 in the MolNFT archive: 13 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1ESL | Insight into E-SELECTIN(SLASH)LIGAND interaction from the crystal structure and mutagenesis of the… | x-ray diffraction | A | — | — |
| 1ESL | Insight into E-SELECTIN(SLASH)LIGAND interaction from the crystal structure and mutagenesis of the… | x-ray diffraction | A | — | — |
| 1G1T | Crystal structure of E-selectin LECTIN/EGF domains complexed with slex | x-ray diffraction | A | — | — |
| 1G1T | Crystal structure of E-selectin LECTIN/EGF domains complexed with slex | x-ray diffraction | A | — | — |
| 4C16 | E-selectin lectin, EGF-like and two SCR domains complexed with glycomimetic antagonist | x-ray diffraction | A, B | — | — |
| 4C16 | E-selectin lectin, EGF-like and two scr domains complexed with glycomimetic antagonist | x-ray diffraction | A, B | — | — |
| 4CSY | E-selectin lectin, EGF-like and two SCR domains complexed with Sialyl Lewis X | x-ray diffraction | A, B | — | — |
| 4CSY | E-selectin lectin, EGF-like and two scr domains complexed with sialyl lewis X | x-ray diffraction | A, B | — | — |
| 6EYI | E-selectin lectin, EGF-like and two scr domains complexed with glycomimetic ligand BW69669 | x-ray diffraction | A | NAG, C4Z, CA | — |
| 6EYJ | E-selectin lectin, EGF-like and two scr domains complexed with glycomimetic ligand NV354 | x-ray diffraction | A, B | NAG, C5H, CA | — |
| 6EYK | E-selectin lectin, EGF-like and two scr domains complexed with glycomimetic ligand NV355 | x-ray diffraction | A | NAG, C5K, CA | — |
| 8R5M | E-selectin complexed with glycomimetic ligand DS0567 | x-ray diffraction | A | NAG, Y6O, CA | — |
| P16581 | AlphaFold monomer V2.0 prediction for E-selectin (P16581) | — | — | — |
Ligands
- CA · Calcium ion · in 4 records
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 4 records
- C4Z · (2~{R})-3-cyclohexyl-2-[(2~{R},3~{S},4~{S},5~{R}, 6~{R})-2-(hydroxymethyl)-6-[(1~{R},2~{R})-2-[(2~{S}, 3~{S},4~{R},5~{S},6~{S})-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl]oxycyclohexyl]oxy-3,5-bis(oxidanyl)oxan-4-yl]oxy-propanoic acid · in 1 record
- C5H · (2~{S})-3-cyclohexyl-2-[(2~{R},3~{S},4~{S},5~{R}, 6~{R})-2-(hydroxymethyl)-3,5-bis(oxidanyl)-6-[(1~{R}, 2~{R})-2-[(2~{R},3~{S},4~{R},5~{S},6~{R})-3,4,5-tris(oxidanyl)-6-(trifluoromethyl)oxan-2-yl]oxycyclohexyl]oxy-oxan-4-yl]oxy-propanoic acid · in 1 record
- C5K · (2~{S})-3-cyclohexyl-2-[(2~{R},3~{S},4~{S},5~{R}, 6~{R})-2-(hydroxymethyl)-6-[(1~{R},2~{R},3~{S})-3-methyl-2-[(2~{R},3~{S},4~{R},5~{S},6~{R})-3,4,5-tris(oxidanyl)-6-(trifluoromethyl)oxan-2-yl]oxy-cyclohexyl]oxy-3,5-bis(oxidanyl)oxan-4-yl]oxy-propanoic acid · in 1 record
- Y6O · (2~{S})-3-cyclohexyl-2-[(2~{R},3~{R},4~{S},5~{S},6~{R})-2-[(1~{R},2~{R},3~{S})-3-ethyl-2-[(2~{S},3~{S},4~{R},5~{S},6~{S})-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-cyclohexyl]oxy-6-(hydroxymethyl)-5-oxidanyl-3-(phenylcarbonyloxy)oxan-4-yl]oxy-propanoic acid · in 1 record
Elsewhere
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