UniProt P15813
Antigen-presenting glycoprotein CD1d (P15813)
Antigen-presenting glycoprotein CD1d (UniProt P15813): 36 experimental structures and 1 predicted model on GenesisL1, 7 ligands bound, 36 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P15813
- Protein
- Antigen-presenting glycoprotein CD1d
- Experimental structures
- 36
- Predicted models
- 1
- Ligands
- 7
- Pockets
- 36 · 4 records with a druggable one
Structures
37 records of P15813 in the MolNFT archive: 36 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1ZT4 | The crystal structure of human CD1d with and without alpha-Galactosylceramide | x-ray diffraction | A, C | — | — |
| 1ZT4 | The crystal structure of human CD1D with and without alpha- galactosylceramide | x-ray diffraction | A, C | — | — |
| 2PO6 | Crystal structure of CD1d-lipid-antigen complexed with Beta-2-Microglobulin, NKT15 Alpha-Chain and… | x-ray diffraction | A, E | — | — |
| 2PO6 | Crystal structure of CD1D-lipid-antigen complexed with beta-2- microglobulin, NKT15 alpha-chain and… | x-ray diffraction | A, E | — | — |
| 3HUJ | Crystal structure of human CD1d-alpha-Galactosylceramide in complex with semi-invariant NKT cell… | x-ray diffraction | A, C | — | — |
| 3HUJ | Crystal structure of human CD1D-alpha-galactosylceramide in complex with semi-invariant nkt cell… | x-ray diffraction | A, C | — | — |
| 3SDX | Crystal structure of human autoreactive-Valpha24 NKT TCR in complex with… | x-ray diffraction | A, C | — | — |
| 3SDX | Crystal structure of human autoreactive-VALPHA24 nkt TCR in complex with… | x-ray diffraction | A, C | — | — |
| 3TZV | Crystal structure of an iNKT TCR in complex with CD1d-lysophosphatidylcholine | x-ray diffraction | C | — | — |
| 3TZV | Crystal structure of an inkt TCR in complex with CD1D- lysophosphatidylcholine | x-ray diffraction | C | — | — |
| 3U0P | Crystal structure of human CD1d-lysophosphatidylcholine | x-ray diffraction | A, C, E | — | — |
| 3U0P | Crystal structure of human CD1D-lysophosphatidylcholine | x-ray diffraction | A, C, E | — | — |
| 3VWJ | Ternary crystal structure of the human NKT TCR-CD1d-C20:2 complex | x-ray diffraction | A | — | — |
| 3VWJ | Ternary crystal structure of the human nkt TCR-CD1D-C20:2 complex | x-ray diffraction | A | — | — |
| 3VWK | Ternary crystal structure of the human NKT TCR-CD1d-4'deoxy-alpha-galactosylceramide complex | x-ray diffraction | A | — | — |
| 3VWK | Ternary crystal structure of the human nkt TCR-CD1D-4'DEOXY-alpha- galactosylceramide complex | x-ray diffraction | A | — | — |
| 4EN3 | Crystal structure of a human Valpha24(-) NKT TCR in complex with CD1d/alpha-galactosylceramide | x-ray diffraction | C | — | — |
| 4EN3 | Crystal structure of a human VALPHA24(-) nkt TCR in complex with CD1D/ALPHA-galactosylceramide | x-ray diffraction | C | — | — |
| 4LHU | Crystal Structure of 9C2 TCR bound to CD1d | x-ray diffraction | A | — | — |
| 4LHU | Crystal structure of 9C2 TCR bound to CD1D | x-ray diffraction | A | — | — |
| 4MNG | Structure of the DP10.7 TCR with CD1d-sulfatide | x-ray diffraction | A, C | — | — |
| 4MNG | Structure of the DP10.7 TCR with CD1D-sulfatide | x-ray diffraction | A, C | — | — |
| 4MQ7 | Structure of human CD1d-sulfatide | x-ray diffraction | A | — | — |
| 4MQ7 | Structure of human CD1D-sulfatide | x-ray diffraction | A | — | — |
| 4WO4 | The molecular bases of DELTA/ALPHA beta T cell-mediated antigen recognition. | x-ray diffraction | A | — | — |
| 4WW2 | Crystal structure of human TCR Alpha Chain-TRAV21-TRAJ8, Beta Chain-TRBV7-8, Antigen-presenting… | x-ray diffraction | C | — | — |
| 4WW2 | Crystal structure of human TCR alpha chain-TRAV21-TRAJ8, beta chain- TRBV7-8, antigen-presenting… | x-ray diffraction | C | — | — |
| 4WWK | Crystal structure of human TCR Alpha Chain-TRAV12-3, Beta Chain-TRBV6-5, Antigen-presenting… | x-ray diffraction | C | — | — |
| 4WWK | Crystal structure of human TCR alpha chain-TRAV12-3, beta chain-TRBV6- 5, antigen-presenting… | x-ray diffraction | C | — | — |
| 6V7Y | Human CD1d presenting alpha-Galactosylceramide in complex with VHH nanobody 1D5 | x-ray diffraction | A | NAG, SO4, AGH, CL | 5 (best 0.85) |
| 6V7Y | Human CD1D presenting alpha-galactosylceramide in complex with vhh nanobody 1D5 | x-ray diffraction | A | NAG, SO4, AGH, CL | — |
| 6V7Z | Human CD1d presenting alpha-Galactosylceramide in complex with VHH nanobody 1D22 | x-ray diffraction | A, C | NAG, AGH, CL, SO4, BGC | 11 (best 0.85) |
| 6V7Z | Human CD1D presenting alpha-galactosylceramide in complex with vhh nanobody 1D22 | x-ray diffraction | A, C | NAG, AGH, CL, BGC | — |
| 6V80 | Crystal structure of human CD1D presenting alpha-galactosylceramide in complex with NKT12 TCR and… | x-ray diffraction | A, F | NAG, AGH | — |
| 8SGM | Crystal Structure of CD1d-lipid complexed with Beta-2-Microglobulin, TCR Alpha-Chain and TCR… | x-ray diffraction | A | NAG, A1AHF, SO4 | 7 (best 0.86) |
| 8SOS | Human CD1d presenting sphingomyelin C24:1 in complex with VHH nanobody 1D17 | x-ray diffraction | A, E | FO4, NAG | 13 (best 0.87) |
| P15813 | AlphaFold monomer V2.0 prediction for antigen-presenting glycoprotein CD1D (P15813) | predicted | A | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 7 records
- AGH · N-{(1S,2R,3S)-1-[(alpha-D-galactopyranosyloxy)methyl]-2,3-dihydroxyheptadecyl}hexacosanamide · in 5 records
- CL · Chloride ion · in 4 records
- SO4 · Sulfate ion · in 4 records
- BGC · beta-D-glucopyranose · in 2 records
- A1AHF · N-[(2S)-3-oxo-1-(beta-L-talopyranosyloxy)octadecan-2-yl]docosanamide · in 1 record
- FO4 · sphingomyelin · in 1 record
Experiment against prediction
- 4WWK chain C against the predicted model P15813: TM-score 0.99, RMSD 0.59 Å
- 4WWK chain C against the predicted model P15813: TM-score 0.99, RMSD 0.59 Å
- 4WO4 chain A against the predicted model P15813: TM-score 0.99, RMSD 0.69 Å
- 8SGM chain A against the predicted model P15813: TM-score 0.99, RMSD 0.68 Å
- 6V7Z chain C against the predicted model P15813: TM-score 0.99, RMSD 0.68 Å
- 6V7Z chain C against the predicted model P15813: TM-score 0.99, RMSD 0.68 Å
- 4EN3 chain C against the predicted model P15813: TM-score 0.99, RMSD 0.65 Å
- 4EN3 chain C against the predicted model P15813: TM-score 0.99, RMSD 0.65 Å
- 4LHU chain A against the predicted model P15813: TM-score 0.99, RMSD 0.69 Å
- 4LHU chain A against the predicted model P15813: TM-score 0.99, RMSD 0.69 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.