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UniProt P13631

Retinoic acid receptor gamma (P13631)

Retinoic acid receptor gamma (UniProt P13631): 12 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt
P13631
Protein
Retinoic acid receptor gamma
Experimental structures
12
Predicted models
1
Ligands
4
Pockets
9 · 3 records with a druggable one

Structures

13 records of P13631 in the MolNFT archive: 12 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
1FCXIsotype selectivity of the human retinoic acid nuclear receptor hrar: the complex with the…x-ray diffractionA——
1FCXIsotype selectivity of the human retinoic acid nuclear receptor hrar: the complex with the…x-ray diffractionA——
1FCYIsotype selectivity of the human retinoic acid nuclear receptor hrar: the complex with the…x-ray diffractionA——
1FCYIsotype selectivity of the human retinoic acid nuclear receptor hrar: the complex with the…x-ray diffractionA——
1FCZIsotype selectivity of the human retinoic acid nuclear receptor hrar: the complex with the…x-ray diffractionA——
1FCZIsotype selectivity of the human retinoic acid nuclear receptor hrar: the complex with the…x-ray diffractionA——
1FD0Isotype selectivity of the human retinoic acid nuclear receptor hrar: the complex with the…x-ray diffractionA——
1FD0Isotype selectivity of the human retinoic acid nuclear receptor hrar: the complex with the…x-ray diffractionA——
5M24RARg mutant-S371Ex-ray diffractionA9CR, LMU, CL3 (best 0.81)
5M24Rarg mutant-S371Ex-ray diffractionA9CR, LMU, CL—
6FX0Structure-based design of Trifarotene (CD5789), a potent and selective RAR gamma agonist for the…x-ray diffractionAE9T3 (best 0.82)
6FX0Structure-based design of trifarotene (CD5789), a potent and selective rar gamma agonist for the…x-ray diffractionAE9T—
P13631AlphaFold monomer V2.0 prediction for retinoic acid receptor gamma (P13631)predictedA—3 (best 0.81)

Ligands

  • 9CR · (9cis)-retinoic acid · in 2 records
  • CL · Chloride ion · in 2 records
  • E9T · 6-[3-(1-adamantyl)-4-oxidanyl-phenyl]naphthalene-2-carboxylic acid · in 2 records
  • LMU · Dodecyl-alpha-D-maltoside · in 2 records

Experiment against prediction

Elsewhere

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