MolNFT v1 · #332719 · protein
AlphaFold monomer V2.0 prediction for retinoic acid receptor gamma (P13631)
P13631: “AlphaFold monomer V2.0 prediction for retinoic acid receptor gamma (P13631)”. 3 pockets (best druggability 0.81). MolNFT v1 #332719 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P13631
- Type
- protein
- Length
- 454 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xb3c0C983Fc44934AC589D7131C08a72544EBB92E
- Molecule
- Retinoic acid receptor gamma
- UniProt
- P13631
- Pockets
- 3 · best druggability 0.81
Structure
1 distinct chain · 41% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Retinoic acid receptor gamma | protein | 454 | 41% helix, 3% strand | P13631 |
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 147 | 0.81 | 0.97 | 26 | empty |
| 2 | 191 | 0.51 | 0.77 | 25 | empty |
| 3 | 93 | 0.42 | 0.78 | 19 | empty |
Compared structures
- 6FX0 · Structure-based design of trifarotene (CD5789), a potent and selective rar gamma agonist… · an experimental structure of the same protein · chain A against A, TM-score 0.52
- 1FCY · Isotype selectivity of the human retinoic acid nuclear receptor hrar: the complex with… · an experimental structure of the same protein · chain A against A, TM-score 0.52
- 1FCY · Isotype selectivity of the human retinoic acid nuclear receptor hrar: the complex with… · an experimental structure of the same protein · chain A against A, TM-score 0.52
- 5M24 · Rarg mutant-S371E · an experimental structure of the same protein · chain A against A, TM-score 0.52
- 1FD0 · Isotype selectivity of the human retinoic acid nuclear receptor hrar: the complex with… · an experimental structure of the same protein · chain A against A, TM-score 0.52
- 1FD0 · Isotype selectivity of the human retinoic acid nuclear receptor hrar: the complex with… · an experimental structure of the same protein · chain A against A, TM-score 0.52
- 1FCZ · Isotype selectivity of the human retinoic acid nuclear receptor hrar: the complex with… · an experimental structure of the same protein · chain A against A, TM-score 0.52
- 1FCZ · Isotype selectivity of the human retinoic acid nuclear receptor hrar: the complex with… · an experimental structure of the same protein · chain A against A, TM-score 0.52
- 1FCX · Isotype selectivity of the human retinoic acid nuclear receptor hrar: the complex with… · an experimental structure of the same protein · chain A against A, TM-score 0.51
- 1FCX · Isotype selectivity of the human retinoic acid nuclear receptor hrar: the complex with… · an experimental structure of the same protein · chain A against A, TM-score 0.51
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P13631
- Elsewhere: UniProt P13631 · AlphaFold DB P13631
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