UniProt P12758
Uridine phosphorylase (P12758)
Uridine phosphorylase (UniProt P12758): 30 experimental structures and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P12758
- Protein
- Uridine phosphorylase
- Experimental structures
- 30
- Predicted models
- 1
- Pockets
- 1 · 1 record with a druggable one
Structures
31 records of P12758 in the MolNFT archive: 30 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1K3F | Uridine Phosphorylase from E. coli, Refined in the Monoclinic Crystal Lattice | x-ray diffraction | A, B, C, D, E, F | — | — |
| 1K3F | Uridine phosphorylase from E. COLI, refined in the monoclinic crystal lattice | x-ray diffraction | A, B, C, D, E, F | — | — |
| 1LX7 | Structure of E. coli uridine phosphorylase at 2.0A | x-ray diffraction | A, B | — | — |
| 1LX7 | Structure of E. COLI uridine phosphorylase at 2.0A | x-ray diffraction | A, B | — | — |
| 1RXC | E. COLI uridine phosphorylase: 5-fluorouracil ribose-1-phosphate complex | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | — | — |
| 1RXC | E. COLI uridine phosphorylase: 5-fluorouracil ribose-1-phosphate complex | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | — | — |
| 1RXS | E. coli uridine phosphorylase: 2'-deoxyuridine phosphate complex | x-ray diffraction | A, a, B, b, C, c, D, d, E, e, F, R, G, P, H, h, I, i, J, j, K, k, L, l, M, m, N, Q, O, o | — | — |
| 1RXS | E. COLI uridine phosphorylase: 2'-deoxyuridine phosphate complex | x-ray diffraction | A, a, B, b, C, c, D, d, E, e, F, R, G, P, H, h, I, i, J, j, K, k, L, l, M, m, N, Q, O, o | — | — |
| 1RXU | E. coli uridine phosphorylase: thymidine phosphate complex | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R | — | — |
| 1RXU | E. COLI uridine phosphorylase: thymidine phosphate complex | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R | — | — |
| 1RXY | E. coli uridine phosphorylase: type-B native | x-ray diffraction | A, B | — | — |
| 1RXY | E. COLI uridine phosphorylase: type-B native | x-ray diffraction | A, B | — | — |
| 1T0U | Crystal structure of E.coli uridine phosphorylase at 2.2 A resolution (Type-A Native) | x-ray diffraction | A, B | — | — |
| 1T0U | Crystal structure of E.COLI uridine phosphorylase at 2.2 a resolution (type-a native) | x-ray diffraction | A, B | — | — |
| 1TGV | Structure of E. coli Uridine Phosphorylase complexed with 5-Fluorouridine and sulfate | x-ray diffraction | A, B | — | — |
| 1TGV | Structure of E. COLI uridine phosphorylase complexed with 5- fluorouridine and sulfate | x-ray diffraction | A, B | — | — |
| 1TGY | Structure of E. coli Uridine Phosphorylase complexed with uracil and ribose 1-phosphate | x-ray diffraction | A, B | — | — |
| 1TGY | Structure of E. COLI uridine phosphorylase complexed with uracil and ribose 1-phosphate | x-ray diffraction | A, B | — | — |
| 1U1C | Structure of E. coli uridine phosphorylase complexed to 5-benzylacyclouridine (BAU) | x-ray diffraction | A, B, C, D, E, F | — | — |
| 1U1C | Structure of E. COLI uridine phosphorylase complexed to 5- benzylacyclouridine (bau) | x-ray diffraction | A, B, C, D, E, F | — | — |
| 1U1D | Structure of e. coli uridine phosphorylase complexed to 5-(phenylthio)acyclouridine (ptau) | x-ray diffraction | A, B, C, D, E, F | — | — |
| 1U1D | Structure of E. COLI uridine phosphorylase complexed to 5- (PHENYLTHIO)ACYCLOURIDINE (ptau) | x-ray diffraction | A, B, C, D, E, F | — | — |
| 1U1E | Structure of e. coli uridine phosphorylase complexed to 5(phenylseleno)acyclouridine (PSAU) | x-ray diffraction | A, B, C, D, E, F | — | — |
| 1U1E | Structure of E. COLI uridine phosphorylase complexed to 5(PHENYLSELENO)ACYCLOURIDINE (psau) | x-ray diffraction | A, B, C, D, E, F | — | — |
| 1U1F | Structure of e. coli uridine phosphorylase complexed to 5-(m-(benzyloxy)benzyl)acyclouridine (BBAU) | x-ray diffraction | A, B, C, D, E, F | — | — |
| 1U1F | Structure of E. COLI uridine phosphorylase complexed to 5-(M- (BENZYLOXY)BENZYL)ACYCLOURIDINE (bbau) | x-ray diffraction | A, B, C, D, E, F | — | — |
| 1U1G | Structure of E. coli uridine phosphorylase complexed to 5-(m-(benzyloxy)benzyl)barbituric acid… | x-ray diffraction | A, B, C, D, E, F | — | — |
| 1U1G | Structure of E. COLI uridine phosphorylase complexed to 5-(M- (BENZYLOXY)BENZYL)BARBITURIC acid… | x-ray diffraction | A, B, C, D, E, F | — | — |
| 3KVV | Trapping of an oxocarbenium ion intermediate in UP crystals | x-ray diffraction | A, B, C, D, E, F | — | — |
| 3KVV | Trapping of an oxocarbenium ion intermediate in up crystals | x-ray diffraction | A, B, C, D, E, F | — | — |
| P12758 | AlphaFold monomer V2.0 prediction for uridine phosphorylase (P12758) | predicted | A | — | 1 (best 0.51) |
Experiment against prediction
- 3KVV chain A against the predicted model P12758: TM-score 1.00, RMSD 0.25 Å
- 3KVV chain A against the predicted model P12758: TM-score 1.00, RMSD 0.25 Å
- 1TGV chain B against the predicted model P12758: TM-score 1.00, RMSD 0.26 Å
- 1TGV chain B against the predicted model P12758: TM-score 1.00, RMSD 0.26 Å
- 1U1F chain A against the predicted model P12758: TM-score 1.00, RMSD 0.28 Å
- 1U1F chain A against the predicted model P12758: TM-score 1.00, RMSD 0.28 Å
- 3KVV chain D against the predicted model P12758: TM-score 1.00, RMSD 0.28 Å
- 3KVV chain D against the predicted model P12758: TM-score 1.00, RMSD 0.28 Å
- 3KVV chain B against the predicted model P12758: TM-score 1.00, RMSD 0.29 Å
- 3KVV chain B against the predicted model P12758: TM-score 1.00, RMSD 0.29 Å
Elsewhere
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