UniProt P11940
Polyadenylate-binding protein 1 (P11940)
Polyadenylate-binding protein 1 (UniProt P11940): 54 experimental structures on GenesisL1, 5 ligands bound, 18 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P11940
- Protein
- Polyadenylate-binding protein 1
- Experimental structures
- 54
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 18 · 2 records with a druggable one
Structures
54 records of P11940 in the MolNFT archive: 54 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1CVJ | X-ray crystal structure of the POLY(A)-binding protein in complex with polyadenylate RNA | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 1CVJ | X-ray crystal structure of the POLY(A)-binding protein in complex with polyadenylate RNA | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 1G9L | Solution structure of the pabc domain of human POLY(A) binding protein | solution nmr | A | — | — |
| 1G9L | Solution structure of the pabc domain of human POLY(A) binding protein | solution nmr | A | — | — |
| 1JGN | Solution structure of the C-terminal PABC domain of human poly(A)-binding protein in complex with… | solution nmr | A | — | — |
| 1JGN | Solution structure of the C-terminal pabc domain of human POLY(A)- binding protein in complex with… | solution nmr | A | — | — |
| 1JH4 | Solution structure of the C-terminal PABC domain of human poly(A)-binding protein in complex with… | solution nmr | A | — | — |
| 1JH4 | Solution structure of the C-terminal pabc domain of human POLY(A)- binding protein in complex with… | solution nmr | A | — | — |
| 2K8G | Solution structure of RRM2 domain of PABP1 | solution nmr | A | — | — |
| 2K8G | Solution structure of RRM2 domain of PABP1 | solution nmr | A | — | — |
| 2RQG | Structure of GSPT1/ERF3A-PABC | solution nmr | B | — | — |
| 2RQG | Structure of GSPT1/ERF3A-pabc | solution nmr | B | — | — |
| 2RQH | Structure of GSPT1/ERF3A-PABC | solution nmr | B | — | — |
| 2RQH | Structure of GSPT1/ERF3A-pabc | solution nmr | B | — | — |
| 2X04 | Crystal structure of the PABC-TNRC6C complex | x-ray diffraction | A, B | — | — |
| 2X04 | Crystal structure of the pabc-TNRC6C complex | x-ray diffraction | A, B | — | — |
| 3KTP | Structural basis of GW182 recognition by poly(A)-binding protein | x-ray diffraction | A | — | — |
| 3KTP | Structural basis of GW182 recognition by POLY(A)-binding protein | x-ray diffraction | A | — | — |
| 3KTR | Structural basis of ataxin-2 recognition by poly(A)-binding protein | x-ray diffraction | A | — | — |
| 3KTR | Structural basis of ataxin-2 recognition by POLY(A)-binding protein | x-ray diffraction | A | — | — |
| 3KUI | Crystal structure of C-terminal domain of PABPC1 in complex with binding region of eRF3a | x-ray diffraction | A | — | — |
| 3KUI | Crystal structure of C-terminal domain of PABPC1 in complex with binding region of ERF3A | x-ray diffraction | A | — | — |
| 3KUJ | Crystal structure of C-terminal domain of PABPC1 in complex with binding region of eRF3a | x-ray diffraction | A | — | — |
| 3KUJ | Crystal structure of C-terminal domain of PABPC1 in complex with binding region of ERF3A | x-ray diffraction | A | — | — |
| 3KUR | Crystal structure of the MLLE domain of poly(A)-binding protein | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 3KUR | Crystal structure of the mlle domain of POLY(A)-binding protein | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 3KUS | Crystal structure of the MLLE domain of poly(A)-binding protein in complex with the binding region… | x-ray diffraction | A, B | — | — |
| 3KUS | Crystal structure of the mlle domain of POLY(A)-binding protein in complex with the binding region… | x-ray diffraction | A, B | — | — |
| 3KUT | Crystal structure of the MLLE domain of poly(A)-binding protein in complex with the binding region… | x-ray diffraction | A, B | — | — |
| 3KUT | Crystal structure of the mlle domain of POLY(A)-binding protein in complex with the binding region… | x-ray diffraction | A, B | — | — |
| 3PKN | Crystal structure of MLLE domain of poly(A) binding protein in complex with PAM2 motif of… | x-ray diffraction | A | — | — |
| 3PKN | Crystal structure of mlle domain of POLY(A) binding protein in complex with PAM2 motif of… | x-ray diffraction | A | — | — |
| 3PTH | The PABC1 MLLE domain bound to the variant PAM2 motif of LARP4B | x-ray diffraction | A | — | — |
| 3PTH | The PABC1 mlle domain bound to the variant PAM2 motif of LARP4B | x-ray diffraction | A | — | — |
| 4F02 | Crystal structure of the PABP-binding site of eIF4G in complex with RRM1-2 of PABP and poly(A) | x-ray diffraction | A, D | — | — |
| 4F02 | Crystal structure of the pabp-binding site of EIF4G in complex with RRM1-2 of pabp and POLY(A) | x-ray diffraction | A, D | — | — |
| 4F25 | Crystal structure of the second RRM domain of human PABPC1 at pH 6.0 | x-ray diffraction | A | — | — |
| 4F25 | Crystal structure of the second rrm domain of human PABPC1 at pH 6.0 | x-ray diffraction | A | — | — |
| 4F26 | Crystal structure of the second RRM domain of human PABPC1 a pH 9.0 | x-ray diffraction | A | — | — |
| 4F26 | Crystal structure of the second rrm domain of human PABPC1 a pH 9.0 | x-ray diffraction | A | — | — |
| 5DX1 | Crystal structure of CARM1, sinefungin, and PABP1 peptide (R455) | x-ray diffraction | F, G, H, I | — | — |
| 5DX8 | Crystal structure of CARM1, sinefungin, and methylated PABP1 peptide (R455) | x-ray diffraction | E, F, G, H | — | — |
| 5DX8 | Crystal structure of CARM1, sinefungin, and methylated PABP1 peptide (R455) | x-ray diffraction | E, F, G, H | — | — |
| 5DXA | Crystal structure of CARM1, sinefungin, and methylated PABP1 peptide (R460) | x-ray diffraction | F, G, I | — | — |
| 5DXA | Crystal structure of CARM1, sinefungin, and methylated PABP1 peptide (R460) | x-ray diffraction | F, G, I | — | — |
| 5LGP | Crystal structure of mouse CARM1 in complex with ligand P1C3S | x-ray diffraction | E, F, G, H | ACE, 8ZB | — |
| 5LGQ | Crystal structure of mouse CARM1 in complex with ligand P2C3s | x-ray diffraction | F, E, G, H | 8ZB | 8 (best 0.81) |
| 5LGQ | Crystal structure of mouse CARM1 in complex with ligand P2C3S | x-ray diffraction | F, E, G, H | 8ZB | — |
| 5LGR | Crystal structure of mouse CARM1 in complex with ligand P1C3u | x-ray diffraction | E, F, G, H | QVR, LPD, ACE | 10 (best 0.82) |
| 5LGR | Crystal structure of mouse CARM1 in complex with ligand P1C3U | x-ray diffraction | E, F, G, H | QVR, ACE | — |
| 5LGS | Crystal structure of mouse CARM1 in complex with ligand P2C3u | x-ray diffraction | E, F, G, H | QVR | — |
| 5LGS | Crystal structure of mouse CARM1 in complex with ligand P2C3U | x-ray diffraction | E, F, G, H | QVR | — |
| 7BN3 | Crystal structure of C-terminal domain of PABPC1 in complex with nucleoprotein from human… | x-ray diffraction | A, B, C | SO4 | — |
| P11940 | AlphaFold monomer V2.0 prediction for polyadenylate-binding protein 1 (P11940) | — | — | — |
Ligands
Elsewhere
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