UniProt P0AFK0
Metalloprotease PmbA (P0AFK0)
Metalloprotease PmbA (UniProt P0AFK0), EC 3.4.-.-: 12 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 208 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0AFK0
- Protein
- Metalloprotease PmbA
- EC
- 3.4.-.-
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 208 · 12 records with a druggable one
Structures
13 records of P0AFK0 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5NJ5 | E. coli Microcin-processing metalloprotease TldD/E with phosphate bound | x-ray diffraction | B, D | — | 15 (best 0.79) |
| 5NJ5 | E. COLI microcin-processing metalloprotease TLDD/E with phosphate bound | x-ray diffraction | B, D | — | 15 (best 0.79) |
| 5NJ9 | E. coli Microcin-processing metalloprotease TldD/E with DRVY angiotensin fragment bound | x-ray diffraction | B, D | NA | 17 (best 0.78) |
| 5NJ9 | E. COLI microcin-processing metalloprotease TLDD/E with drvy angiotensin fragment bound | x-ray diffraction | B, D | NA | 17 (best 0.78) |
| 5NJA | E. coli Microcin-processing metalloprotease TldD/E with angiotensin analogue bound | x-ray diffraction | B, D | NA | 17 (best 0.79) |
| 5NJA | E. COLI microcin-processing metalloprotease TLDD/E with angiotensin analogue bound | x-ray diffraction | B, D | NA | 17 (best 0.79) |
| 5NJB | E. coli Microcin-processing metalloprotease TldD/E with actinonin bound | x-ray diffraction | B, D | — | 18 (best 0.74) |
| 5NJB | E. COLI microcin-processing metalloprotease TLDD/E with actinonin bound | x-ray diffraction | B, D | — | 18 (best 0.74) |
| 5NJC | E. coli Microcin-processing metalloprotease TldD/E (TldD E263A mutant) with hexapeptide bound | x-ray diffraction | B, D | NA | 17 (best 0.75) |
| 5NJC | E. COLI microcin-processing metalloprotease TLDD/E (tldd E263A mutant) with hexapeptide bound | x-ray diffraction | B, D | NA | 17 (best 0.75) |
| 5NJF | E. coli Microcin-processing metalloprotease TldD/E (TldD H262A mutant) with pentapeptide bound | x-ray diffraction | B, D | NA | 17 (best 0.77) |
| 5NJF | E. COLI microcin-processing metalloprotease TLDD/E (tldd H262A mutant) with pentapeptide bound | x-ray diffraction | B, D | NA | 17 (best 0.77) |
| P0AFK0 | AlphaFold monomer V2.0 prediction for metalloprotease pmba (P0AFK0) | predicted | A | — | 6 (best 0.49) |
Ligands
- NA · Sodium ion · in 8 records
Experiment against prediction
- 5NJA chain D against the predicted model P0AFK0: TM-score 0.99, RMSD 0.63 Å
- 5NJA chain D against the predicted model P0AFK0: TM-score 0.99, RMSD 0.63 Å
- 5NJA chain B against the predicted model P0AFK0: TM-score 0.99, RMSD 0.64 Å
- 5NJA chain B against the predicted model P0AFK0: TM-score 0.99, RMSD 0.64 Å
- 5NJ9 chain D against the predicted model P0AFK0: TM-score 0.99, RMSD 0.65 Å
- 5NJ9 chain D against the predicted model P0AFK0: TM-score 0.99, RMSD 0.65 Å
- 5NJB chain B against the predicted model P0AFK0: TM-score 0.99, RMSD 0.65 Å
- 5NJB chain B against the predicted model P0AFK0: TM-score 0.99, RMSD 0.65 Å
- 5NJ9 chain B against the predicted model P0AFK0: TM-score 0.99, RMSD 0.66 Å
- 5NJ9 chain B against the predicted model P0AFK0: TM-score 0.99, RMSD 0.66 Å
Elsewhere
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