UniProt P0A988
Beta sliding clamp (P0A988)
Beta sliding clamp (UniProt P0A988), EC 2.7.7.7: 92 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 121 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0A988
- Protein
- Beta sliding clamp
- EC
- 2.7.7.7
- Experimental structures
- 92
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 121 · 16 records with a druggable one
Structures
93 records of P0A988 in the MolNFT archive: 92 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1JQJ | Mechanism of Processivity Clamp Opening by the Delta Subunit Wrench of the Clamp Loader Complex of… | x-ray diffraction | A, B | — | — |
| 1JQJ | Mechanism of processivity clamp opening by the delta subunit wrench of the clamp loader complex of… | x-ray diffraction | A, B | — | — |
| 1JQL | Mechanism of Processivity Clamp Opening by the Delta Subunit Wrench of the Clamp Loader Complex of… | x-ray diffraction | A | — | — |
| 1JQL | Mechanism of processivity clamp opening by the delta subunit wrench of the clamp loader complex of… | x-ray diffraction | A | — | — |
| 1MMI | E. COLI DNA polymerase beta subunit | x-ray diffraction | A, B | — | — |
| 1MMI | E. COLI DNA polymerase beta subunit | x-ray diffraction | A, B | — | — |
| 2POL | Three-dimensional structure of the beta subunit of escherichia COLI DNA polymerase III holoenzyme… | x-ray diffraction | A, B | — | — |
| 2POL | Three-dimensional structure of the beta subunit of escherichia COLI DNA polymerase III holoenzyme… | x-ray diffraction | A, B | — | — |
| 2XUR | The G157C mutation in the Escherichia coli sliding clamp specifically affects initiation of… | x-ray diffraction | A, B | — | — |
| 2XUR | The G157C mutation in the escherichia COLI sliding clamp specifically affects initiation of… | x-ray diffraction | A, B | — | — |
| 3BEP | Structure of a sliding clamp on DNA | x-ray diffraction | A, B | — | — |
| 3BEP | Structure of a sliding clamp on DNA | x-ray diffraction | A, B | — | — |
| 3D1E | Crystal structure of E. coli sliding clamp (beta) bound to a polymerase II peptide | x-ray diffraction | A, B | — | — |
| 3D1E | Crystal structure of E. COLI sliding clamp (beta) bound to a polymerase II peptide | x-ray diffraction | A, B | — | — |
| 3D1F | Crystal structure of E. coli sliding clamp (beta) bound to a polymerase III peptide | x-ray diffraction | A, B | — | — |
| 3D1F | Crystal structure of E. COLI sliding clamp (beta) bound to a polymerase III peptide | x-ray diffraction | A, B | — | — |
| 3D1G | Structure of a small molecule inhibitor bound to a DNA sliding clamp | x-ray diffraction | A, B | — | — |
| 3D1G | Structure of a small molecule inhibitor bound to a DNA sliding clamp | x-ray diffraction | A, B | — | — |
| 3F1V | E. coli Beta Sliding Clamp, 148-153 Ala Mutant | x-ray diffraction | A, B | — | — |
| 3F1V | E. COLI beta sliding clamp, 148-153 ala mutant | x-ray diffraction | A, B | — | — |
| 3PWE | Crystal structure of the E. coli beta clamp mutant R103C, I305C, C260S, C333S at 2.2A resolution | x-ray diffraction | A, B | — | — |
| 3PWE | Crystal structure of the E. COLI beta clamp mutant R103C, I305C, C260S, C333S at 2.2A resolution | x-ray diffraction | A, B | — | — |
| 3Q4J | Structure of a small peptide ligand bound to E.coli DNA sliding clamp | x-ray diffraction | A, B, C, D, E, F | — | — |
| 3Q4J | Structure of a small peptide ligand bound to E.COLI DNA sliding clamp | x-ray diffraction | A, B, C, D, E, F | — | — |
| 3Q4K | Structure of a small peptide ligand bound to E.coli DNA sliding clamp | x-ray diffraction | A, B | — | — |
| 3Q4K | Structure of a small peptide ligand bound to E.COLI DNA sliding clamp | x-ray diffraction | A, B | — | — |
| 3Q4L | Structure of a small peptide ligand bound to E.coli DNA sliding clamp | x-ray diffraction | A, B | — | — |
| 3Q4L | Structure of a small peptide ligand bound to E.COLI DNA sliding clamp | x-ray diffraction | A, B | — | — |
| 3QSB | Structure of E. coli polIIIbeta with (Z)-5-(1-((4'-Fluorobiphenyl-4-yl)methoxyimino)butyl)-2,2-dimet… | x-ray diffraction | A, B | — | — |
| 3QSB | Structure of E. COLI poliiibeta with (Z)-5-(1-((4'-fluorobiphenyl-4… | x-ray diffraction | A, B | — | — |
| 4K3K | E. Coli sliding clamp in complex with (S)-2-(4-methylpentanamido)-3-phenylpropanoic acid | x-ray diffraction | A, B | — | — |
| 4K3K | E. COLI sliding clamp in complex with (S)-2-(4-methylpentanamido)-3- phenylpropanoic acid | x-ray diffraction | A, B | — | — |
| 4K3L | E. coli sliding clamp in complex with AcLF dipeptide | x-ray diffraction | A, B | — | — |
| 4K3L | E. COLI sliding clamp in complex with aclf dipeptide | x-ray diffraction | A, B | — | — |
| 4K3M | E.coli sliding clamp in complex with AcALDLF peptide | x-ray diffraction | A, B | — | — |
| 4K3M | E.COLI sliding clamp in complex with acaldlf peptide | x-ray diffraction | A, B | — | — |
| 4K3O | E. coli sliding clamp in complex with AcQADLF | x-ray diffraction | A, B | — | — |
| 4K3O | E. COLI sliding clamp in complex with acqadlf | x-ray diffraction | A, B | — | — |
| 4K3P | E. coli sliding clamp in complex with AcQLALF | x-ray diffraction | A, B | — | — |
| 4K3P | E. COLI sliding clamp in complex with acqlalf | x-ray diffraction | A, B | — | — |
| 4K3Q | E. coli sliding clamp in complex with AcQLDAF | x-ray diffraction | A, B | — | — |
| 4K3Q | E. COLI sliding clamp in complex with acqldaf | x-ray diffraction | A, B | — | — |
| 4K3R | E. coli sliding clamp in complex with AcQLDLA | x-ray diffraction | A, B | — | — |
| 4K3R | E. COLI sliding clamp in complex with acqldla | x-ray diffraction | A, B | — | — |
| 4K3S | E. coli sliding clamp in P1 crystal space group | x-ray diffraction | A, B | — | — |
| 4K3S | E. COLI sliding clamp in P1 crystal space group | x-ray diffraction | A, B | — | — |
| 4MJP | E. coli sliding clamp in complex with (R)-Vedaprofen | x-ray diffraction | A, B | — | — |
| 4MJP | E. COLI sliding clamp in complex with (R)-vedaprofen | x-ray diffraction | A, B | — | — |
| 4MJQ | E. coli sliding clamp in complex with Bromfenac | x-ray diffraction | A, B | — | — |
| 4MJQ | E. COLI sliding clamp in complex with bromfenac | x-ray diffraction | A, B | — | — |
| 4MJR | E. coli sliding clamp in complex with (S)-Carprofen | x-ray diffraction | A, B | — | — |
| 4MJR | E. COLI sliding clamp in complex with (S)-carprofen | x-ray diffraction | A, B | — | — |
| 4N94 | E. coli sliding clamp in complex with 3,4-difluorobenzamide | x-ray diffraction | A, B | — | — |
| 4N94 | E. COLI sliding clamp in complex with 3,4-difluorobenzamide | x-ray diffraction | A, B | — | — |
| 4N95 | E. coli sliding clamp in complex with 5-chloroindoline-2,3-dione | x-ray diffraction | B, A | — | — |
| 4N95 | E. COLI sliding clamp in complex with 5-chloroindoline-2,3-dione | x-ray diffraction | B, A | — | — |
| 4N96 | E. coli sliding clamp in complex with 6-nitroindazole | x-ray diffraction | A, B | — | — |
| 4N96 | E. COLI sliding clamp in complex with 6-nitroindazole | x-ray diffraction | A, B | — | — |
| 4N97 | E. coli sliding clamp in complex with 5-nitroindole | x-ray diffraction | A, B | — | — |
| 4N97 | E. COLI sliding clamp in complex with 5-nitroindole | x-ray diffraction | A, B | — | — |
33 records more on the page itself.
Ligands
Experiment against prediction
- 4N99 chain A against the predicted model P0A988: TM-score 0.99, RMSD 0.67 Å
- 4N99 chain A against the predicted model P0A988: TM-score 0.99, RMSD 0.67 Å
- 3BEP chain A against the predicted model P0A988: TM-score 0.99, RMSD 0.71 Å
- 3BEP chain A against the predicted model P0A988: TM-score 0.99, RMSD 0.71 Å
- 3D1E chain A against the predicted model P0A988: TM-score 0.99, RMSD 0.72 Å
- 3D1E chain A against the predicted model P0A988: TM-score 0.99, RMSD 0.72 Å
- 4K3S chain B against the predicted model P0A988: TM-score 0.99, RMSD 0.72 Å
- 4K3S chain B against the predicted model P0A988: TM-score 0.99, RMSD 0.72 Å
- 4N95 chain B against the predicted model P0A988: TM-score 0.99, RMSD 0.73 Å
- 4N95 chain B against the predicted model P0A988: TM-score 0.99, RMSD 0.73 Å
Elsewhere
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