UniProt P09850
Endo-1,4-beta-xylanase (P09850)
Endo-1,4-beta-xylanase (UniProt P09850), EC 3.2.1.8: 45 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P09850
- Protein
- Endo-1,4-beta-xylanase
- EC
- 3.2.1.8
- Experimental structures
- 45
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 9 · 4 records with a druggable one
Structures
46 records of P09850 in the MolNFT archive: 45 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1BCX | Mutational and crystallographic analyses of the active site residues of the bacillus circulans… | x-ray diffraction | A | — | — |
| 1BCX | Mutational and crystallographic analyses of the active site residues of the bacillus circulans… | x-ray diffraction | A | — | — |
| 1BVV | Sugar ring distortion in the glycosyl-enzyme intermediate of a family G/11 xylanase | x-ray diffraction | A | — | — |
| 1BVV | Sugar ring distortion in the glycosyl-enzyme intermediate of a family G/11 xylanase | x-ray diffraction | A | — | — |
| 1C5H | Hydrogen bonding and catalysis: an unexpected explanation for how a single amino acid substitution… | x-ray diffraction | A | — | — |
| 1C5H | Hydrogen bonding and catalysis: an unexpected explanation for how a single amino acid substitution… | x-ray diffraction | A | — | — |
| 1C5I | Hydrogen bonding and catalysis: an unexpected explanation for how a single amino acid substitution… | x-ray diffraction | A | — | — |
| 1C5I | Hydrogen bonding and catalysis: an unexpected explanation for how a single amino acid substitution… | x-ray diffraction | A | — | — |
| 1HV0 | Dissecting electrostatic interactions and the pH-dependent activity of a family 11 glycosidase | x-ray diffraction | A | — | — |
| 1HV0 | Dissecting electrostatic interactions and the pH-dependent activity of a family 11 glycosidase | x-ray diffraction | A | — | — |
| 1HV1 | Dissecting electrostatic interactions and the pH-dependent activity of a family 11 glycosidase | x-ray diffraction | A | — | — |
| 1HV1 | Dissecting electrostatic interactions and the pH-dependent activity of a family 11 glycosidase | x-ray diffraction | A | — | — |
| 1XNB | High-resolution structures of xylanases from B. circulans and T. harzianum identify a new folding… | x-ray diffraction | A | — | — |
| 1XNB | High-resolution structures of xylanases from B. circulans and T. harzianum identify a new folding… | x-ray diffraction | A | — | — |
| 1XNC | Thermostabilization of the bacillus circulans xylanase, by the introduction of disulfide bonds | x-ray diffraction | A | — | — |
| 1XNC | Thermostabilization of the bacillus circulans xylanase, by the introduction of disulfide bonds | x-ray diffraction | A | — | — |
| 2BVV | Sugar ring distortion in the glycosyl-enzyme intermediate of a family G/11 xylanase. | x-ray diffraction | A | — | — |
| 2BVV | Sugar ring distortion in the glycosyl-enzyme intermediate of a family G/11 xylanase. | x-ray diffraction | A | — | — |
| 3LB9 | Crystal structure of the B. circulans cpA123 circular permutant | x-ray diffraction | A, B, C | — | — |
| 3LB9 | Crystal structure of the B. circulans CPA123 circular permutant | x-ray diffraction | A, B, C | — | — |
| 3VZJ | Crystal structure of the Bacillus circulans endo-beta-(1,4)-xylanase (BcX) E172H mutant | x-ray diffraction | A, B, C, D | — | — |
| 3VZJ | Crystal structure of the bacillus circulans endo-beta-(1,4)-xylanase (bcx) E172H mutant | x-ray diffraction | A, B, C, D | — | — |
| 3VZK | Crystal structure of the Bacillus circulans endo-beta-(1,4)-xylanase (BcX) N35E mutant | x-ray diffraction | A, B | — | — |
| 3VZK | Crystal structure of the bacillus circulans endo-beta-(1,4)-xylanase (bcx) N35E mutant | x-ray diffraction | A, B | — | — |
| 3VZL | Crystal structure of the Bacillus circulans endo-beta-(1,4)-xylanase (BcX) N35H mutant | x-ray diffraction | A, B, C, D | — | — |
| 3VZL | Crystal structure of the bacillus circulans endo-beta-(1,4)-xylanase (bcx) N35H mutant | x-ray diffraction | A, B, C, D | — | — |
| 3VZM | Crystal structure of the Bacillus circulans endo-beta-(1,4)-xylanase (BcX) E172H mutant with Glu78… | x-ray diffraction | A | — | — |
| 3VZM | Crystal structure of the bacillus circulans endo-beta-(1,4)-xylanase (bcx) E172H mutant with GLU78… | x-ray diffraction | A | — | — |
| 3VZN | Crystal structure of the Bacillus circulans endo-beta-(1,4)-xylanase (BcX) N35E mutant with Glu78… | x-ray diffraction | A, B | — | — |
| 3VZN | Crystal structure of the bacillus circulans endo-beta-(1,4)-xylanase (bcx) N35E mutant with GLU78… | x-ray diffraction | A, B | — | — |
| 3VZO | Crystal structure of the Bacillus circulans endo-beta-(1,4)-xylanase (BcX) N35H mutant with Glu78… | x-ray diffraction | A | — | — |
| 3VZO | Crystal structure of the bacillus circulans endo-beta-(1,4)-xylanase (bcx) N35H mutant with GLU78… | x-ray diffraction | A | — | — |
| 7VUG | Cryo-EM structure of a class a orphan GPCR in complex with gi | electron microscopy | R | 7ZQ | — |
| 7VUH | Cryo-EM structure of a class a orphan GPCR | electron microscopy | R | 7ZQ | — |
| 7VUI | Cryo-EM structure of a class A orphan GPCR | electron microscopy | R | 7ZQ | — |
| 7VUI | Cryo-EM structure of a class a orphan GPCR | electron microscopy | R | 7ZQ | — |
| 7VUJ | Cryo-EM structure of a class a orphan GPCR | electron microscopy | R | 7ZQ | — |
| 7XN9 | Crystal structure of SSTR2 and L-054,522 complex | x-ray diffraction | A | GI9 | 4 (best 0.82) |
| 7XN9 | Crystal structure of SSTR2 and L-054,522 complex | x-ray diffraction | A | GI9 | — |
| 7XNA | Crystal structure of somatostatin receptor 2 (SSTR2) with peptide antagonist CYN 154806 | x-ray diffraction | A | — | — |
| 7XNA | Crystal structure of somatostatin receptor 2 (SSTR2) with peptide antagonist cyn 154806 | x-ray diffraction | A | ACE, NH2 | — |
| 8QXY | Xylanase from Bacillus circulans mutant E78Q bound to xylotriose | x-ray diffraction | A, B | XYP, ZN | 1 (best 0.72) |
| 8QXZ | Xylanase from Bacillus circulans mutant E78Q/Y69A | x-ray diffraction | A, B | ZN | 1 (best 0.73) |
| 8QY2 | Xylanase from Bacillus circulans mutant E78Q/F125A | x-ray diffraction | A | ZN | 1 (best 0.31) |
| 8QY3 | Xylanase from Bacillus circulans mutant E78Q/F125A bound to xylotriose | x-ray diffraction | A | XYP, ZN | 1 (best 0.30) |
| P09850 | AlphaFold monomer V2.0 prediction for endo-1,4-beta-xylanase (P09850) | predicted | A | — | 1 (best 0.52) |
Ligands
- 7ZQ · 3-chloranyl-N-[2-oxidanylidene-2-[[(1S)-1-phenylethyl]amino]ethyl]benzamide · in 5 records
- ZN · Zinc ion · in 4 records
- GI9 · tert-butyl (2S)-6-azanyl-2-[[(2R,3S)-3-(1H-indol-3-yl)-2-[[4-(2-oxidanylidene-3H-benzimidazol-1-yl)piperidin-1-yl]carbonylamino]butanoyl]amino]hexanoate · in 2 records
- XYP · beta-D-xylopyranose · in 2 records
- ACE · Acetyl group · in 1 record
- NH2 · Amino group · in 1 record
Experiment against prediction
- 8QXY chain A against the predicted model P09850: TM-score 1.00, RMSD 0.25 Å
- 8QXZ chain A against the predicted model P09850: TM-score 1.00, RMSD 0.28 Å
- 8QXY chain B against the predicted model P09850: TM-score 1.00, RMSD 0.28 Å
- 8QXZ chain B against the predicted model P09850: TM-score 1.00, RMSD 0.31 Å
- 3VZO chain A against the predicted model P09850: TM-score 1.00, RMSD 0.35 Å
- 3VZO chain A against the predicted model P09850: TM-score 1.00, RMSD 0.35 Å
- 3VZN chain A against the predicted model P09850: TM-score 0.99, RMSD 0.40 Å
- 3VZN chain A against the predicted model P09850: TM-score 0.99, RMSD 0.40 Å
- 3VZK chain A against the predicted model P09850: TM-score 0.99, RMSD 0.40 Å
- 3VZK chain A against the predicted model P09850: TM-score 0.99, RMSD 0.40 Å
Elsewhere
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