UniProt P09528
Ferritin heavy chain (P09528)
Ferritin heavy chain (UniProt P09528), EC 1.16.3.1, 2.3.1.-: 27 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 220 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P09528
- Protein
- Ferritin heavy chain
- EC
- 1.16.3.1, 2.3.1.-, 2.3.1.48
- Experimental structures
- 27
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 220 · 11 records with a druggable one
Structures
28 records of P09528 in the MolNFT archive: 27 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3WNW | Structure of Mouse H-chain modified ferritin | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | — | — |
| 3WNW | Structure of mouse H-chain modified ferritin | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | — | — |
| 5OBA | Structure of a modified mouse H-chain ferritin with a lanthanide binding motif | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X | FE | 20 (best 0.79) |
| 5OBA | Structure of a modified mouse H-chain ferritin with a lanthanide binding motif | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X | FE | — |
| 5OBB | Structure of a modified mouse H chain ferritin with a lanthanide binding motif in complex with… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X | TB | 20 (best 0.74) |
| 5OBB | Structure of a modified mouse H chain ferritin with a lanthanide binding motif in complex with… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X | TB | — |
| 6S61 | Apoferritin from mouse at 1.84 angstrom resolution | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X | FE, ZN | — |
| 6S61 | Apoferritin from mouse at 1.84 ångström resolution | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X | FE, ZN | — |
| 6SHT | Molecular structure of mouse apoferritin resolved at 2.7 Angstroms with the Glacios cryo-microscope | electron microscopy | A | FE, MG | — |
| 6SHT | Molecular structure of mouse apoferritin resolved at 2.7 ångströms with the glacios cryo-microscope | electron microscopy | A | FE, MG | — |
| 6V21 | Mouse heavy chain apoferritin determined using single-particle cryo-EM at 200 kev | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X | — | — |
| 7A4M | Cryo-EM structure of mouse heavy-chain apoferritin at 1.22 A | electron microscopy | A | FE, ZN | — |
| 7A4M | Cryo-EM structure of mouse heavy-chain apoferritin at 1.22 a | electron microscopy | A | FE, ZN | — |
| 7KOD | Cryo-EM structure of heavy chain mouse apoferritin | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X | — | 20 (best 0.75) |
| 7KOD | Cryo-EM structure of heavy chain mouse apoferritin | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X | — | — |
| 7TB3 | Cryo-EM structure of mbp-kix-apoferritin | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X | — | — |
| 7TBH | cryo-EM structure of MBP-KIX-apoferritin complex with peptide 7 | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X | — | 20 (best 0.83) |
| 7TBH | Cryo-EM structure of mbp-kix-apoferritin complex with peptide 7 | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X | — | — |
| 8BK9 | Cryo-EM structure of mouse heavy-chain apoferritin at 2.1 A plunged 5ms after mixing with… | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, V, W, X, Y | FE | 20 (best 0.69) |
| 8BKA | Cryo-EM structure of mouse heavy-chain apoferritin at 2.7 A plunged 35ms after mixing with… | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, V, W, X, Y | FE | 20 (best 0.76) |
| 8EMQ | Mouse apoferritin heavy chain with zinc determined using single-particle cryo-EM with Apollo camera. | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X | ZN, FE | 20 (best 0.80) |
| 8J5A | Single-particle cryo-EM structure of mouse apoferritin at 1.19 Angstrom resolution (Dataset A) | electron microscopy | A | NA | — |
| 8PVC | Structure of mouse heavy-chain apoferritin determined by cryoEM at 100 keV | electron microscopy | A | FE, ZN | — |
| 8RQB | Cryo-EM structure of mouse heavy-chain apoferritin | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X | FE, ZN | 20 (best 0.80) |
| 8TU7 | Cryo-EM structure of Apoferritin collected by EPU on Glacios at 2.5 Angstrom resolution | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X | FE, ZN | 20 (best 0.80) |
| 8TU8 | Cryo-EM structure of Apoferritin collected by SerialEM on Glacios at 2.1 Angstrom resolution | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X | FE, ZN | 20 (best 0.75) |
| 8TUE | Cryo-EM structure of Apoferritin collected by Leginon on Glacios at 2.1 Angstrom resolution | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X | ZN, FE | 20 (best 0.69) |
| P09528 | AlphaFold monomer V2.0 prediction for ferritin heavy chain (P09528) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7KOD chain C against the predicted model P09528: TM-score 1.00, RMSD 0.18 Å
- 7KOD chain C against the predicted model P09528: TM-score 1.00, RMSD 0.18 Å
- 5OBB chain O against the predicted model P09528: TM-score 1.00, RMSD 0.18 Å
- 5OBB chain O against the predicted model P09528: TM-score 1.00, RMSD 0.18 Å
- 7KOD chain L against the predicted model P09528: TM-score 1.00, RMSD 0.19 Å
- 7KOD chain L against the predicted model P09528: TM-score 1.00, RMSD 0.19 Å
- 7KOD chain X against the predicted model P09528: TM-score 1.00, RMSD 0.19 Å
- 7KOD chain X against the predicted model P09528: TM-score 1.00, RMSD 0.19 Å
- 7KOD chain N against the predicted model P09528: TM-score 1.00, RMSD 0.20 Å
- 7KOD chain N against the predicted model P09528: TM-score 1.00, RMSD 0.20 Å
Elsewhere
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