UniProt P08670
Vimentin (P08670)
Vimentin (UniProt P08670): 43 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 31 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P08670
- Protein
- Vimentin
- Experimental structures
- 43
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 31 · 3 records with a druggable one
Structures
44 records of P08670 in the MolNFT archive: 43 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1GK4 | Human vimentin coil 2B fragment (CYS2) | x-ray diffraction | A, B, C, D, E, F | — | 7 (best 0.64) |
| 1GK4 | Human vimentin coil 2B fragment (CYS2) | x-ray diffraction | A, B, C, D, E, F | — | — |
| 1GK6 | Human vimentin coil 2B fragment linked to GCN4 leucine zipper (Z2B) | x-ray diffraction | A, B | — | — |
| 1GK6 | Human vimentin coil 2B fragment linked to GCN4 leucine zipper (Z2B) | x-ray diffraction | A, B | — | — |
| 1GK7 | Human vimentin coil 1A fragment (1A) | x-ray diffraction | A | SO4 | — |
| 1GK7 | Human vimentin coil 1A fragment (1A) | x-ray diffraction | A | — | — |
| 3G1E | X-ray crystal structure of coil 1A of human vimentin | x-ray diffraction | A, B | — | — |
| 3G1E | X-ray crystal structure of coil 1A of human vimentin | x-ray diffraction | A, B | — | — |
| 3KLT | Crystal structure of a vimentin fragment | x-ray diffraction | A, B, C, D | — | — |
| 3KLT | Crystal structure of a vimentin fragment | x-ray diffraction | A, B, C, D | — | — |
| 3S4R | Crystal structure of vimentin coil1A/1B fragment with a stabilizing mutation | x-ray diffraction | A, B | — | — |
| 3S4R | Crystal structure of vimentin COIL1A/1B fragment with a stabilizing mutation | x-ray diffraction | A, B | — | — |
| 3SSU | Crystal structure of vimentin coil1A/1B fragment | x-ray diffraction | A, B | — | — |
| 3SSU | Crystal structure of vimentin COIL1A/1B fragment | x-ray diffraction | A, B | — | — |
| 3SWK | Crystal structure of vimentin coil1B fragment | x-ray diffraction | A, B | — | — |
| 3SWK | Crystal structure of vimentin COIL1B fragment | x-ray diffraction | A, B | — | — |
| 3TRT | Crystal structure of stabilised vimentin coil2 fragment | x-ray diffraction | A, B | — | — |
| 3TRT | Crystal structure of stabilised vimentin COIL2 fragment | x-ray diffraction | A, B | — | — |
| 3UF1 | Crystal Structure of Vimentin (fragment 144-251) from Homo sapiens, Northeast Structural Genomics… | x-ray diffraction | A, B, C, D | — | — |
| 3UF1 | Crystal structure of vimentin (fragment 144-251) from homo sapiens, northeast structural genomics… | x-ray diffraction | A, B, C, D | — | — |
| 4MCY | Immune Receptor | x-ray diffraction | C | — | — |
| 4MCY | Immune receptor | x-ray diffraction | C | — | — |
| 4MCZ | Immune Receptor | x-ray diffraction | C | — | — |
| 4MCZ | Immune receptor | x-ray diffraction | C | — | — |
| 4MD0 | Immune Receptor | x-ray diffraction | C | — | — |
| 4MD0 | Immune receptor | x-ray diffraction | C | — | — |
| 4MD5 | Immune Receptor | x-ray diffraction | C | — | — |
| 4MD5 | Immune receptor | x-ray diffraction | C | — | — |
| 4MDI | Immune Receptor | x-ray diffraction | C | — | — |
| 4MDI | Immune receptor | x-ray diffraction | C | — | — |
| 4MDJ | Immune Receptor | x-ray diffraction | C | — | — |
| 4MDJ | Immune receptor | x-ray diffraction | C | — | — |
| 4YPC | Trimeric crystal structure of vimentin coil1B fragment | x-ray diffraction | A | — | — |
| 4YPC | Trimeric crystal structure of vimentin COIL1B fragment | x-ray diffraction | A | — | — |
| 4YV3 | Trimeric crystal structure of vimentin coil1B fragment | x-ray diffraction | A, B, C | — | — |
| 4YV3 | Trimeric crystal structure of vimentin COIL1B fragment | x-ray diffraction | A, B, C | — | — |
| 5WHF | Crystal structure of vimentin coil 1B packed in a high-order filamentous form | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 5WHF | Crystal structure of vimentin coil 1B packed in a high-order filamentous form | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 6YXK | Crystal structure of ACPA 3F3 in complex with cit-vimentin 59-74 | x-ray diffraction | C | — | — |
| 6YXK | Crystal structure of acpa 3F3 in complex with cit-vimentin 59-74 | x-ray diffraction | C | CIR | — |
| 8RVE | Vimentin intermediate filament | electron microscopy | 0, 1, 2, 3, 4, 5, 6, 7, 8, 9, A, AA, AB, AC, AD, AE, AF, AG, AH, AI, AJ, AK, AL, AM, AN, AO, AP, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z, a, b, c, d, e, f, g, h, i, j, k, l, m, n, o, p, q, r, s, t, u, v, w, x, y, z | — | 20 (best 0.85) |
| 8TRQ | T cell recognition of citrullinated vimentin peptide presented by HLA-DR4 | x-ray diffraction | C | — | 1 (best 0.69) |
| 8TRR | T cell recognition of citrullinated vimentin peptide presented by HLA-DR4 | x-ray diffraction | C, H | SO4 | 2 (best 0.49) |
| P08670 | AlphaFold monomer V2.0 prediction for vimentin (P08670) | predicted | A | — | 1 (best 0.36) |
Ligands
Experiment against prediction
- 1GK6 chain B against the predicted model P08670: TM-score 0.95, RMSD 0.56 Å
- 3SSU chain B against the predicted model P08670: TM-score 0.94, RMSD 0.46 Å
- 3SSU chain A against the predicted model P08670: TM-score 0.93, RMSD 0.67 Å
- 3G1E chain A against the predicted model P08670: TM-score 0.93, RMSD 0.49 Å
- 1GK4 chain F against the predicted model P08670: TM-score 0.92, RMSD 0.91 Å
- 1GK4 chain D against the predicted model P08670: TM-score 0.92, RMSD 1.05 Å
- 4YV3 chain B against the predicted model P08670: TM-score 0.92, RMSD 0.96 Å
- 1GK7 chain A against the predicted model P08670: TM-score 0.91, RMSD 0.57 Å
- 3TRT chain A against the predicted model P08670: TM-score 0.91, RMSD 1.04 Å
- 5WHF chain D against the predicted model P08670: TM-score 0.91, RMSD 1.43 Å
Elsewhere
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