UniProt P08174
Complement decay-accelerating factor (P08174)
Complement decay-accelerating factor (UniProt P08174): 55 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P08174
- Protein
- Complement decay-accelerating factor
- Experimental structures
- 55
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 4 · 2 records with a druggable one
Structures
56 records of P08174 in the MolNFT archive: 55 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1H03 | Human CD55 domains 3 & 4 | x-ray diffraction | P, Q | — | — |
| 1H03 | Human CD55 domains 3 & 4 | x-ray diffraction | P, Q | — | — |
| 1H04 | Human CD55 domains 3 & 4 | x-ray diffraction | P | — | — |
| 1H04 | Human CD55 domains 3 & 4 | x-ray diffraction | P | — | — |
| 1H2P | Human CD55 domains 3 & 4 | x-ray diffraction | P | — | — |
| 1H2P | Human CD55 domains 3 & 4 | x-ray diffraction | P | — | — |
| 1H2Q | Human CD55 domains 3 & 4 | x-ray diffraction | P | — | — |
| 1H2Q | Human CD55 domains 3 & 4 | x-ray diffraction | P | — | — |
| 1M11 | structural model of human decay-accelerating factor bound to echovirus 7 from cryo-electron… | electron microscopy | R | — | — |
| 1M11 | Structural model of human decay-accelerating factor bound to echovirus 7 from cryo-electron… | electron microscopy | R | — | — |
| 1NWV | Solution structure of a functionally active component of decay accelerating factor | solution nmr | A | — | — |
| 1NWV | Solution structure of a functionally active component of decay accelerating factor | solution nmr | A | — | — |
| 1OJV | Decay accelerating factor (CD55): the structure of an intact human complement regulator. | x-ray diffraction | A, B | — | — |
| 1OJV | Decay accelerating factor (CD55): the structure of an intact human complement regulator. | x-ray diffraction | A, B | — | — |
| 1OJW | Decay accelerating factor (CD55): the structure of an intact human complement regulator. | x-ray diffraction | A, B | — | — |
| 1OJW | Decay accelerating factor (CD55): the structure of an intact human complement regulator. | x-ray diffraction | A, B | — | — |
| 1OJY | Decay accelerating factor (cd55): the structure of an intact human complement regulator. | x-ray diffraction | A, B, C, D | — | — |
| 1OJY | Decay accelerating factor (CD55): the structure of an intact human complement regulator. | x-ray diffraction | A, B, C, D | — | — |
| 1OK1 | Decay accelerating factor (cd55) : the structure of an intact human complement regulator. | x-ray diffraction | A, B | — | — |
| 1OK1 | Decay accelerating factor (CD55): the structure of an intact human complement regulator. | x-ray diffraction | A, B | — | — |
| 1OK2 | Decay accelerating factor (CD55): the structure of an intact human complement regulator. | x-ray diffraction | A, B | — | — |
| 1OK2 | Decay accelerating factor (CD55): the structure of an intact human complement regulator. | x-ray diffraction | A, B | — | — |
| 1OK3 | Decay accelerating factor (cd55): the structure of an intact human complement regulator. | x-ray diffraction | A, B | — | — |
| 1OK3 | Decay accelerating factor (CD55): the structure of an intact human complement regulator. | x-ray diffraction | A, B | — | — |
| 1OK9 | Decay accelerating factor (CD55): The structure of an intact human complement regulator. | x-ray diffraction | A, B | — | — |
| 1OK9 | Decay accelerating factor (CD55): the structure of an intact human complement regulator. | x-ray diffraction | A, B | — | — |
| 1UOT | Human CD55 domains 3 & 4 | x-ray diffraction | P | — | — |
| 1UOT | Human CD55 domains 3 & 4 | x-ray diffraction | P | — | — |
| 1UPN | Complex of echovirus type 12 with domains 3 and 4 of its receptor decay accelerating factor (CD55)… | electron microscopy | E | — | — |
| 1UPN | Complex of echovirus type 12 with domains 3 and 4 of its receptor decay accelerating factor (CD55)… | electron microscopy | E | — | — |
| 2C8I | Complex Of Echovirus Type 12 With Domains 1, 2, 3 and 4 Of Its Receptor Decay Accelerating Factor… | electron microscopy | E | — | — |
| 2C8I | Complex of echovirus type 12 with domains 1, 2, 3 and 4 of its receptor decay accelerating factor… | electron microscopy | E | — | — |
| 2QZD | Fitted structure of SCR4 of DAF into cryoEM density | electron microscopy | A | — | — |
| 2QZD | Fitted structure of SCR4 of daf into cryoem density | electron microscopy | A | — | — |
| 2QZF | SCR1 of DAF from 1ojv fitted into cryoEM density | electron microscopy | A | — | — |
| 2QZF | SCR1 of daf from 1OJV fitted into cryoem density | electron microscopy | A | — | — |
| 2QZH | SCR2/3 of DAF from the NMR structure 1nwv fitted into a cryoEM reconstruction of CVB3-RD complexed… | electron microscopy | A | — | — |
| 2QZH | SCR2/3 of daf from the NMR structure 1NWV fitted into a cryoem reconstruction of CVB3-rd complexed… | electron microscopy | A | — | — |
| 3IYP | The Interaction of Decay-accelerating Factor with Echovirus 7 | electron microscopy | F | — | — |
| 3IYP | The interaction of decay-accelerating factor with echovirus 7 | electron microscopy | F | — | — |
| 3J24 | CryoEM reconstruction of complement decay-accelerating factor | electron microscopy | B | — | — |
| 3J24 | Cryoem reconstruction of complement decay-accelerating factor | electron microscopy | B | — | — |
| 5FOA | Crystal structure of human complement C3B in complex with daf (CCP2-4) | x-ray diffraction | E, F | — | — |
| 6ILJ | Cryo-EM structure of echovirus 6 complexed with its attachment receptor CD55 at pH 5.5 | electron microscopy | E | — | — |
| 6ILK | Cryo-EM structure of Echovirus 6 complexed with its attachment receptor CD55 at PH 7.4 | electron microscopy | E | — | — |
| 6ILK | Cryo-EM structure of echovirus 6 complexed with its attachment receptor CD55 at pH 7.4 | electron microscopy | E | — | — |
| 6LA5 | Cryo-EM structure of echovirus 11 complexed with its attaching receptor CD55 at pH 7.4 | electron microscopy | E | — | — |
| 6LA5 | Cryo-EM structure of echovirus 11 complexed with its attaching receptor CD55 at pH 7.4 | electron microscopy | E | — | — |
| 7C9W | E30 F-particle in complex with CD55 | electron microscopy | E | — | — |
| 7C9W | E30 F-particle in complex with CD55 | electron microscopy | E | — | — |
| 7DO4 | Crystal structure of CD97-CD55 complex | x-ray diffraction | B | NAG | — |
| 7VY5 | Coxsackievirus B3 (VP3-234Q) incubation with CD55 at PH7.4 | electron microscopy | E | — | — |
| 7VY6 | Coxsackievirus B3(VP3-234N) incubate with CD55 at pH7.4 | electron microscopy | E | — | 1 (best 0.70) |
| 7VY6 | Coxsackievirus B3(VP3-234N) incubate with CD55 at PH7.4 | electron microscopy | E | — | — |
| 8B9F | Structure of Echovirus 11 complexed with DAF (CD55) calculated from symmetry expansion | electron microscopy | E | — | 3 (best 0.64) |
| P08174 | AlphaFold monomer V2.0 prediction for complement decay-accelerating factor (P08174) | predicted | A | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 1 record
Experiment against prediction
- 2QZD chain A against the predicted model P08174: TM-score 0.99, RMSD 0.35 Å
- 2QZD chain A against the predicted model P08174: TM-score 0.99, RMSD 0.35 Å
- 1OJY chain D against the predicted model P08174: TM-score 0.98, RMSD 0.78 Å
- 1OJY chain D against the predicted model P08174: TM-score 0.98, RMSD 0.78 Å
- 1OJW chain A against the predicted model P08174: TM-score 0.98, RMSD 0.79 Å
- 1OJW chain A against the predicted model P08174: TM-score 0.98, RMSD 0.79 Å
- 2QZF chain A against the predicted model P08174: TM-score 0.98, RMSD 0.40 Å
- 2QZF chain A against the predicted model P08174: TM-score 0.98, RMSD 0.40 Å
- 1OJY chain C against the predicted model P08174: TM-score 0.98, RMSD 0.94 Å
- 1OJY chain C against the predicted model P08174: TM-score 0.98, RMSD 0.94 Å
Elsewhere
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