UniProt P07305
Histone H1.0 (P07305)
Histone H1.0 (UniProt P07305): 24 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P07305
- Protein
- Histone H1.0
- Experimental structures
- 24
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 7 · 4 records with a druggable one
Structures
25 records of P07305 in the MolNFT archive: 24 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6HQ1 | Solution structure of the globular domain from human histone H1.0 | solution nmr | A | — | — |
| 6HQ1 | Solution structure of the globular domain from human histone H1.0 | solution nmr | A | — | — |
| 6LA2 | 343 bp di-nucleosome harboring cohesive DNA termini assembled with linker histone H1.0 | x-ray diffraction | S, T | — | — |
| 6LA2 | 343 bp di-nucleosome harboring cohesive DNA termini assembled with linker histone H1.0 | x-ray diffraction | S, T | — | — |
| 6LA8 | 349 bp di-nucleosome harboring cohesive DNA termini assembled with linker histone H1.0 | x-ray diffraction | S | — | — |
| 6LA8 | 349 bp di-nucleosome harboring cohesive DNA termini assembled with linker histone H1.0 | x-ray diffraction | S | — | — |
| 6LA9 | 349 bp di-nucleosome harboring cohesive DNA termini assembled with linker histone H1.0 (high… | x-ray diffraction | S, T | CA | 1 (best 0.69) |
| 6LA9 | 349 bp di-nucleosome harboring cohesive DNA termini assembled with linker histone H1.0 (high… | x-ray diffraction | S, T | — | — |
| 6LAB | 169 bp nucleosome, harboring cohesive DNA termini, assembled with linker histone H1.0 | x-ray diffraction | U, V | — | 1 (best 0.71) |
| 6LAB | 169 bp nucleosome, harboring cohesive DNA termini, assembled with linker histone H1.0 | x-ray diffraction | U, V | — | — |
| 6N88 | Cryo-EM structure of the Importin7:Importin beta:Histone H1.0 complex | electron microscopy | C | — | 1 (best 0.29) |
| 6N88 | Cryo-EM structure of the IMPORTIN7:IMPORTIN BETA:HISTONE H1.0 complex | electron microscopy | C | — | — |
| 6N89 | Cryo-EM structure of the Importin beta:Histone H1.0 complex | electron microscopy | B | — | — |
| 6N89 | Cryo-EM structure of the importin BETA:HISTONE H1.0 complex | electron microscopy | B | — | — |
| 7COW | 353 bp di-nucleosome harboring cohesive DNA termini with linker histone H1.0 | x-ray diffraction | S, T | — | — |
| 7COW | 353 bp di-nucleosome harboring cohesive DNA termini with linker histone H1.0 | x-ray diffraction | S, T | — | — |
| 7DBP | Linker histone defines structure and self-association behaviour of the 177 bp human chromosome | electron microscopy | K | — | 2 (best 0.69) |
| 7DBP | Linker histone defines structure and self-association behaviour of the 177 bp human chromosome | electron microscopy | K | — | — |
| 7K5X | Cryo-EM structure of a chromatosome containing human linker histone H1.0 | electron microscopy | U | — | — |
| 7K5X | Cryo-EM structure of a chromatosome containing human linker histone H1.0 | electron microscopy | U | — | — |
| 7XVL | Crystal Structure of Nucleosome-H1.0 Linker Histone Assembly (sticky-169an DNA fragment) | x-ray diffraction | o | — | — |
| 7XX6 | Crystal Structure of Nucleosome-H1.0 Linker Histone Assembly (sticky-169a DNA fragment) | x-ray diffraction | o, p | CA | 2 (best 0.72) |
| 8TB9 | PRC2-J119-450 monomer bound to H1-nucleosome | electron microscopy | A | — | — |
| 9IPU | cryo-EM structure of the RNF168(1-193)/UbcH5c-Ub ubiquitylation module bound to H1.0-K63-Ub3… | electron microscopy | I | — | — |
| P07305 | AlphaFold monomer V2.0 prediction for histone H1.0 (P07305) | predicted | A | — | — |
Ligands
- CA · Calcium ion · in 2 records
Experiment against prediction
- 9IPU chain I against the predicted model P07305: TM-score 1.00, RMSD 0.00 Å
- 6LA2 chain S against the predicted model P07305: TM-score 0.94, RMSD 0.87 Å
- 6LA2 chain S against the predicted model P07305: TM-score 0.94, RMSD 0.87 Å
- 6LA2 chain T against the predicted model P07305: TM-score 0.94, RMSD 0.87 Å
- 7K5X chain U against the predicted model P07305: TM-score 0.93, RMSD 0.88 Å
- 7K5X chain U against the predicted model P07305: TM-score 0.93, RMSD 0.88 Å
- 6LA9 chain T against the predicted model P07305: TM-score 0.92, RMSD 0.99 Å
- 6LA9 chain T against the predicted model P07305: TM-score 0.92, RMSD 0.99 Å
- 6LA8 chain S against the predicted model P07305: TM-score 0.91, RMSD 1.06 Å
- 6LA8 chain S against the predicted model P07305: TM-score 0.91, RMSD 1.06 Å
Elsewhere
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