UniProt P07285
Anthranilate phosphoribosyltransferase (P07285)
Anthranilate phosphoribosyltransferase (UniProt P07285), EC 2.4.2.18: 10 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 24 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P07285
- Protein
- Anthranilate phosphoribosyltransferase
- EC
- 2.4.2.18
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 24 · 6 records with a druggable one
Structures
11 records of P07285 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7DSJ | Anthranilate phosphoribosyltransferase from Saccharomyces cerevisiae in complex with PRPP and Mg | x-ray diffraction | A, B | PRP, MG | 5 (best 0.77) |
| 7DSJ | Anthranilate phosphoribosyltransferase from saccharomyces cerevisiae in complex with prpp and mg | x-ray diffraction | A, B | PRP, MG | — |
| 7DSM | Anthranilate phosphoribosyltransferase from Saccharomyces cerevisiae | x-ray diffraction | A, B | — | 4 (best 0.63) |
| 7DSM | Anthranilate phosphoribosyltransferase from saccharomyces cerevisiae | x-ray diffraction | A, B | — | — |
| 7DSO | Anthranilate phosphoribosyltransferase from Saccharomyces cerevisiae in complex with… | x-ray diffraction | A, B | FA0 | 4 (best 0.61) |
| 7DSO | Anthranilate phosphoribosyltransferase from saccharomyces cerevisiae in complex with… | x-ray diffraction | A, B | FA0 | — |
| 7DSP | Anthranilate phosphoribosyltransferase variant Ser121Ala from Saccharomyces cerevisiae with Mg bound | x-ray diffraction | B, A | MG | 4 (best 0.64) |
| 7DSP | Anthranilate phosphoribosyltransferase variant SER121ALA from saccharomyces cerevisiae with mg bound | x-ray diffraction | B, A | MG | — |
| 7DSR | Anthranilate phosphoribosyltransferase variant Gly141Asn from Saccharomyces cerevisiae in complex… | x-ray diffraction | A, B | FA0 | 6 (best 0.65) |
| 7DSR | Anthranilate phosphoribosyltransferase variant GLY141ASN from saccharomyces cerevisiae in complex… | x-ray diffraction | A, B | FA0 | — |
| P07285 | AlphaFold monomer V2.0 prediction for anthranilate phosphoribosyltransferase (P07285) | predicted | A | — | 1 (best 0.74) |
Ligands
Experiment against prediction
- 7DSJ chain A against the predicted model P07285: TM-score 0.98, RMSD 0.82 Å
- 7DSJ chain A against the predicted model P07285: TM-score 0.98, RMSD 0.82 Å
- 7DSO chain A against the predicted model P07285: TM-score 0.98, RMSD 0.87 Å
- 7DSO chain A against the predicted model P07285: TM-score 0.98, RMSD 0.87 Å
- 7DSJ chain B against the predicted model P07285: TM-score 0.98, RMSD 0.94 Å
- 7DSJ chain B against the predicted model P07285: TM-score 0.98, RMSD 0.94 Å
- 7DSR chain B against the predicted model P07285: TM-score 0.98, RMSD 0.86 Å
- 7DSR chain B against the predicted model P07285: TM-score 0.98, RMSD 0.86 Å
- 7DSO chain B against the predicted model P07285: TM-score 0.98, RMSD 0.90 Å
- 7DSO chain B against the predicted model P07285: TM-score 0.98, RMSD 0.90 Å
Elsewhere
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