UniProt P06873
Proteinase K (P06873)
Proteinase K (UniProt P06873), EC 3.4.21.64: 382 experimental structures on GenesisL1, 41 ligands bound, 66 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P06873
- Protein
- Proteinase K
- EC
- 3.4.21.64
- Experimental structures
- 382
- Predicted models
- 0
- Ligands
- 41
- Pockets
- 66 · 0 records with a druggable one
Structures
382 records of P06873 in the MolNFT archive: 382 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1BJR | Complex formed between proteolytically generated lactoferrin fragment and proteinase K | x-ray diffraction | E | — | — |
| 1BJR | Complex formed between proteolytically generated lactoferrin fragment and proteinase K | x-ray diffraction | E | — | — |
| 1CNM | Enhancement of catalytic efficiency of proteinase K through exposure to anhydrous organic solvent… | x-ray diffraction | A | — | — |
| 1CNM | Enhancement of catalytic efficiency of proteinase K through exposure to anhydrous organic solvent… | x-ray diffraction | A | — | — |
| 1EGQ | Enhancement of enzyme activity through three-phase partitioning: crystal structure of a modified… | x-ray diffraction | A | — | — |
| 1EGQ | Enhancement of enzyme activity through three-phase partitioning: crystal structure of a modified… | x-ray diffraction | A | — | — |
| 1HT3 | Mercury induced modifications in the stereochemistry of the active site through cys-73 in a serine… | x-ray diffraction | A | — | — |
| 1HT3 | Mercury induced modifications in the stereochemistry of the active site through cys-73 in a serine… | x-ray diffraction | A | — | — |
| 1IC6 | Structure of a serine protease proteinase K from tritirachium album limber at 0.98 a resolution | x-ray diffraction | A | — | — |
| 1IC6 | Structure of a serine protease proteinase K from tritirachium album limber at 0.98 a resolution | x-ray diffraction | A | — | — |
| 1OYO | Regulation of protease activity by melanin: Crystal structure of the complex formed between… | x-ray diffraction | A | — | — |
| 1OYO | Regulation of protease activity by melanin: crystal structure of the complex formed between… | x-ray diffraction | A | — | — |
| 1P7V | Structure of a complex formed between Proteinase K and a designed heptapeptide inhibitor… | x-ray diffraction | A | — | — |
| 1P7V | Structure of a complex formed between proteinase K and a designed heptapeptide inhibitor… | x-ray diffraction | A | — | — |
| 1P7W | Crystal structure of the complex of Proteinase K with a designed heptapeptide inhibitor… | x-ray diffraction | A | — | — |
| 1P7W | Crystal structure of the complex of proteinase K with a designed heptapeptide inhibitor… | x-ray diffraction | A | — | — |
| 1PEK | Structure of the complex of proteinase K with a substrate-analogue hexa-peptide inhibitor at 2.2… | x-ray diffraction | E | — | — |
| 1PEK | Structure of the complex of proteinase K with a substrate-analogue hexa-peptide inhibitor at 2.2… | x-ray diffraction | E | — | — |
| 1PFG | Strategy to design inhibitors: Structure of a complex of Proteinase K with a designed octapeptide… | x-ray diffraction | A | — | — |
| 1PFG | Strategy to design inhibitors: structure of a complex of proteinase K with a designed octapeptide… | x-ray diffraction | A | — | — |
| 1PJ8 | Structure of a ternary complex of proteinase K, mercury and a substrate-analogue hexapeptide at 2.2… | x-ray diffraction | A | — | — |
| 1PJ8 | Structure of a ternary complex of proteinase K, mercury and a substrate-analogue hexapeptide at 2.2… | x-ray diffraction | A | — | — |
| 1PTK | Studies on the inhibitory action of mercury upon proteinase K | x-ray diffraction | A | — | — |
| 1PTK | Studies on the inhibitory action of mercury upon proteinase K | x-ray diffraction | A | — | — |
| 2DP4 | Crystal structure of the complex formed between proteinase K and a human lactoferrin fragment at… | x-ray diffraction | E | — | — |
| 2DP4 | Crystal structure of the complex formed between proteinase K and a human lactoferrin fragment at… | x-ray diffraction | E | — | — |
| 2DQK | Crystal structure of the complex of proteinase K with a specific lactoferrin peptide… | x-ray diffraction | A | — | — |
| 2DQK | Crystal structure of the complex of proteinase K with a specific lactoferrin peptide… | x-ray diffraction | A | — | — |
| 2DUJ | Crystal structure of the complex formed between proteinase K and a synthetic peptide… | x-ray diffraction | A | — | — |
| 2DUJ | Crystal structure of the complex formed between proteinase K and a synthetic peptide… | x-ray diffraction | A | — | — |
| 2G4V | anomalous substructure of proteinase K | x-ray diffraction | A | — | — |
| 2G4V | Anomalous substructure of proteinase K | x-ray diffraction | A | — | — |
| 2HD4 | Crystal structure of proteinase K inhibited by a lactoferrin octapeptide… | x-ray diffraction | A | — | — |
| 2HD4 | Crystal structure of proteinase K inhibited by a lactoferrin octapeptide… | x-ray diffraction | A | — | — |
| 2HPZ | Crystal structure of proteinase K complex with a synthetic peptide KLKLLVVIRLK at 1.69 A resolution | x-ray diffraction | A | — | — |
| 2HPZ | Crystal structure of proteinase K complex with a synthetic peptide klkllvvirlk at 1.69 a resolution | x-ray diffraction | A | — | — |
| 2ID8 | Crystal structure of Proteinase K | x-ray diffraction | A | — | — |
| 2ID8 | Crystal structure of proteinase K | x-ray diffraction | A | — | — |
| 2PKC | Crystal structure of calcium-free proteinase K at 1.5 ångströms resolution | x-ray diffraction | A | — | — |
| 2PKC | Crystal structure of calcium-free proteinase K at 1.5 ångströms resolution | x-ray diffraction | A | — | — |
| 2PQ2 | Structure of serine proteinase K complex with a highly flexible hydrophobic peptide at 1.8A… | x-ray diffraction | A | — | — |
| 2PQ2 | Structure of serine proteinase K complex with a highly flexible hydrophobic peptide at 1.8A… | x-ray diffraction | A | — | — |
| 2PRK | Synchrotron X-ray data collection and restrained least-squares refinement of the crystal structure… | x-ray diffraction | A | — | — |
| 2PRK | Synchrotron X-ray data collection and restrained least-squares refinement of the crystal structure… | x-ray diffraction | A | — | — |
| 2PWA | Crystal Structure of the complex of Proteinase K with Alanine Boronic acid at 0.83A resolution | x-ray diffraction | A | — | — |
| 2PWA | Crystal structure of the complex of proteinase K with alanine boronic acid at 0.83A resolution | x-ray diffraction | A | — | — |
| 2PWB | Crystal structure of the complex of proteinase K with coumarin at 1.9 A resolution | x-ray diffraction | A | — | — |
| 2PWB | Crystal structure of the complex of proteinase K with coumarin at 1.9 a resolution | x-ray diffraction | A | — | — |
| 2PYZ | Crystal structure of the complex of proteinase K with auramine at 1.8A resolution | x-ray diffraction | A | — | — |
| 2PYZ | Crystal structure of the complex of proteinase K with auramine at 1.8A resolution | x-ray diffraction | A | — | — |
| 2V8B | SAD Structure solution of Proteinase K grown in selenate solution | x-ray diffraction | A | — | — |
| 2V8B | Sad structure solution of proteinase K grown in selenate solution | x-ray diffraction | A | — | — |
| 3AJ8 | X-ray analysis of Crystal of Proteinase K Obtained from H2O Solution Using PEG 8000 | x-ray diffraction | A | — | — |
| 3AJ8 | X-ray analysis of crystal of proteinase K obtained from H2O solution using peg 8000 | x-ray diffraction | A | — | — |
| 3AJ9 | X-ray analysis of Crystal of Proteinase K Obtained from D2O Solution Using PEG 8000 | x-ray diffraction | A | — | — |
| 3AJ9 | X-ray analysis of crystal of proteinase K obtained from D2O solution using peg 8000 | x-ray diffraction | A | — | — |
| 3D9Q | Proteinase K by LB nanotemplate method before high X-Ray dose on ESRF ID23-1 beamline | x-ray diffraction | X | — | — |
| 3D9Q | Proteinase K by lb nanotemplate method before high X-ray dose on esrf ID23-1 beamline | x-ray diffraction | X | — | — |
| 3DDZ | Proteinase K by LB nanotemplate method after the first step of high X-Ray dose on ESRF ID23-1… | x-ray diffraction | X | — | — |
| 3DDZ | Proteinase K by lb nanotemplate method after the first step of high X-ray dose on esrf ID23-1… | x-ray diffraction | X | — | — |
322 records more on the page itself.
Ligands
- SO4 · Sulfate ion · in 138 records
- CA · Calcium ion · in 87 records
- NO3 · Nitrate ion · in 40 records
- CL · Chloride ion · in 7 records
- NA · Sodium ion · in 5 records
- 47E · (2R)-(3-chlorophenyl)(hydroxy)ethanoic acid · in 3 records
- I3C · 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid · in 3 records
- PR · Praseodymium ion · in 3 records
- WCO · Co-substituted alpha-Keggin · in 3 records
- 46P · 4-methyl-5-(1-methyl-1H-imidazol-2-yl)-1,3-thiazol-2-amine · in 2 records
- 47S · 3-(dimethylamino)benzohydrazide · in 2 records
- 47Y · 3-[(4E)-4-imino-5,6-dimethylfuro[2,3-d]pyrimidin-3(4H)-yl]-N,N-dimethylpropan-1-amine · in 2 records
- 483 · 2-(1H-imidazol-1-yl)-N-(trans-4-methylcyclohexyl)acetamide · in 2 records
- 8G2 · (4-methoxycarbonylphenyl)methylazanium · in 2 records
- AMH · Trans-4-aminomethylcyclohexane-1-carboxylic acid · in 2 records
- BCN · Bicine · in 2 records
- CLW · Chlorzoxazone · in 2 records
- GGG · glycylglycylglycine · in 2 records
- HBD · 4-hydroxybenzamide · in 2 records
- KCO · Co-substituted beta-keggin · in 2 records
- MHA · (carbamoylmethyl-carboxymethyl-amino)-acetic acid · in 2 records
- R5N · Ni-substituted Keggin silicotungstate · in 2 records
- R5Q · Co-substituted keggin silicotungstate · in 2 records
- TOU · Thiourea · in 2 records
- WNI · Ni-substituted alpha-Keggin · in 2 records
- XCO · Co-substituted beta-keggin · in 2 records
- YEY · 2-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-pyrrole · in 2 records
- 479 · 4-oxo-N-[(1S)-1-(pyridin-3-yl)ethyl]-4-(thiophen-2-yl) butanamide · in 1 record
- 4AQ · 2-(1H-indol-3-yl)-N-[(1-methyl-1H-pyrrol-2-yl) methyl]ethanamine · in 1 record
- F91 · N-(pyridin-4-ylmethyl)-2,3-dihydro-1,4-benzodioxin-6-amine · in 1 record
Elsewhere
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