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Ligand · AMH

AMH · Trans-4-aminomethylcyclohexane-1-carboxylic acid

AMH, Trans-4-aminomethylcyclohexane-1-carboxylic acid (C8 H15 N O2, 157.2 g/mol), in the MolNFT structures on GenesisL1: bound in 8 records (4 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and…

Component
AMH
Formula
C8 H15 N O2
Class
ligand
Structures
8
PDB entries
4

Binding sites

AMH in 8 structures; the first of them:

  • 5RPG · PanDDA analysis group deposition -- Proteinase K changed state model for fragment Frag… · AMH A302 · binds LYS118, ASN119, ARG121, ASN122, CYS123, PRO124, VAL127
  • 5V3C · Crystal structure of TGT in complex with 4-(aminomethane)cyclohexane-1-carboxylic acid · AMH A402 · binds TYR106, ASP156, CYS158, GLN203, GLY229, GLY230, LEU231, ALA232 and 2 more
  • 6NMB · Tranexamic Acid is an Active Site Inhibitor of Urokinase Plasminogen Activator · AMH A302 · binds ASP189, SER190, CYS191, GLN192, SER195, VAL213, SER214, TRP215 and 4 more
  • 6YZC · Trypsin inhibitor in complex with bovine trypsin · AMH A302 · binds HIS57, ASP189, SER190, CYS191, GLN192, GLY193, SER195, VAL213 and 6 more
  • 5RPG · Pandda analysis group deposition -- proteinase K changed state model for fragment frag… · AMH A302 · binds LYS118, ASN119, ARG121, CYS123, PRO124, VAL127
  • 5V3C · Crystal structure of tgt in complex with 4-(AMINOMETHANE)CYCLOHEXANE- 1-carboxylic acid · AMH A402 · binds TYR106, ASP156, CYS158, GLN203, GLY229, GLY230, LEU231, ALA232 and 2 more
  • 6NMB · Tranexamic acid is an active site inhibitor of urokinase plasminogen activator · AMH A302 · binds ASP189, SER190, CYS191, GLN192, SER195, VAL213, TRP215, GLY216 and 2 more
  • 6YZC · Trypsin inhibitor in complex with bovine trypsin · AMH A302 · binds HIS57, ASP189, SER190, GLN192, SER195, SER214, TRP215, GLY216 and 2 more

Residues it binds most

GLY 12, SER 10, CYS 13, VAL 13, ASP 12, GLN 12, TRP 10, ASN 2, HIS 3, ALA 2 (residue and the binding sites it lines).

Found with

  • CA · Calcium ion
  • ZN · Zinc ion
  • NO3 · Nitrate ion
  • SO4 · Sulfate ion
  • DMS · Dimethyl sulfoxide
  • EDO · 1,2-ethanediol
  • PEG · Di(hydroxyethyl)ether
  • PGE · Triethylene glycol

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