UniProt P03899
NADH-ubiquinone oxidoreductase chain 3 (P03899)
NADH-ubiquinone oxidoreductase chain 3 (UniProt P03899), EC 1.6.5.3, 7.1.1.2: 42 experimental structures on GenesisL1, 3 ligands bound, 92 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P03899
- Protein
- NADH-ubiquinone oxidoreductase chain 3
- EC
- 1.6.5.3, 7.1.1.2
- Experimental structures
- 42
- Predicted models
- 0
- Ligands
- 3
- Pockets
- 92 · 32 records with a druggable one
Structures
42 records of P03899 in the MolNFT archive: 42 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6G2J | Mouse mitochondrial complex I in the active state | electron microscopy | A | 3PE, PC1 | 4 (best 0.88) |
| 6G2J | Mouse mitochondrial complex I in the active state | electron microscopy | A | 3PE, PC1 | — |
| 6G72 | Mouse mitochondrial complex I in the deactive state | electron microscopy | A | — | 3 (best 0.82) |
| 6G72 | Mouse mitochondrial complex I in the deactive state | electron microscopy | A | — | — |
| 6ZR2 | Cryo-EM structure of respiratory complex I in the active state from Mus musculus at 3.1 A | electron microscopy | A | PC1, 3PE | 4 (best 0.90) |
| 6ZR2 | Cryo-EM structure of respiratory complex I in the active state from mus musculus at 3.1 a | electron microscopy | A | PC1, 3PE | — |
| 6ZTQ | Cryo-EM structure of respiratory complex I from Mus musculus inhibited by piericidin A at 3.0 A | electron microscopy | A | PC1, 3PE | 3 (best 0.89) |
| 6ZTQ | Cryo-EM structure of respiratory complex I from mus musculus inhibited by piericidin a at 3.0 a | electron microscopy | A | PC1, 3PE | — |
| 7AK5 | Cryo-EM structure of respiratory complex I in the deactive state from Mus musculus at 3.2 A | electron microscopy | A | 3PE | — |
| 7AK5 | Cryo-EM structure of respiratory complex I in the deactive state from mus musculus at 3.2 a | electron microscopy | A | 3PE | — |
| 7AK6 | Cryo-EM structure of ND6-P25L mutant respiratory complex I from mus musculus at 3.8 a | electron microscopy | A | 3PE | — |
| 7B93 | Cryo-EM structure of mitochondrial complex I from Mus musculus inhibited by IACS-2858 at 3.0 A | electron microscopy | A | PC1, 3PE | 3 (best 0.89) |
| 7B93 | Cryo-EM structure of mitochondrial complex I from mus musculus inhibited by iacs-2858 at 3.0 a | electron microscopy | A | PC1, 3PE | — |
| 7PSA | The acetogenin-bound complex I of Mus musculus resolved to 3.4 angstroms | electron microscopy | A | PC1, 3PE | 4 (best 0.88) |
| 8C2S | Cryo-EM structure NDUFS4 knockout complex I from Mus musculus heart (Class 1). | electron microscopy | A | PC1, 3PE | 4 (best 0.89) |
| 8CA3 | Cryo-EM structure NDUFS4 knockout complex I from Mus musculus heart (Class 2). | electron microscopy | A | PC1, 3PE | 4 (best 0.90) |
| 8IAP | Respiratory complex Peripheral Arm of CI, focus-refined map of type I, Wild type mouse under… | electron microscopy | A | 3PE | 2 (best 0.86) |
| 8IB4 | Respiratory complex CI:CIII2, type IA, Wild type mouse under cold temperature | electron microscopy | A | 3PE | 2 (best 0.90) |
| 8IB5 | Respiratory complex Peripheral Arm of CI, focus-refined map of type IA, Wild type mouse under cold… | electron microscopy | A | 3PE | 1 (best 0.87) |
| 8IB9 | Respiratory complex CI:CIII2, type IB, Wild type mouse under cold temperature | electron microscopy | A | 3PE | 3 (best 0.90) |
| 8IBD | Respiratory complex CI:CIII2, type II, Wild type mouse under cold temperature | electron microscopy | A | 3PE, PC1 | 3 (best 0.90) |
| 8IBE | Respiratory complex Peripheral Arm of CI, focus-refined map of type II, Wild type mouse under cold… | electron microscopy | A | 3PE, PC1 | 4 (best 0.87) |
| 8IC2 | Respiratory complex CI:CIII2, type I, PERK -/- mouse under cold temperature | electron microscopy | A | 3PE | 3 (best 0.89) |
| 8OM1 | Mitochondrial complex I from Mus musculus in the active state | electron microscopy | A | PC1, 3PE | 3 (best 0.90) |
| 8PW6 | C respirasome from murine liver | electron microscopy | A1 | PC1, 3PE | 2 (best 0.88) |
| 8PW7 | A respirasome from murine liver | electron microscopy | A1 | PC1, 3PE | 2 (best 0.89) |
| 8RGP | Closed Complex I from murine brain | electron microscopy | A | PC1, 3PE | 4 (best 0.89) |
| 8RGQ | Open Complex I from murine liver | electron microscopy | A | PC1, 3PE | 2 (best 0.91) |
| 8RGR | Closed Complex I from murine liver | electron microscopy | A | PC1, 3PE | 3 (best 0.89) |
| 8XNL | Respiratory complex Peripheral Arm of CI, close form A, focus-refined map of type I, Wild type… | electron microscopy | A | 3PE, UQ9 | — |
| 8XNM | Respiratory complex Peripheral Arm of CI, close form B, focus-refined map of type I, Wild type… | electron microscopy | A | 3PE | 2 (best 0.87) |
| 8XNO | Respiratory complex Peripheral Arm of CI, close form A, focus-refined map of type IA, Wild type… | electron microscopy | A | 3PE | 1 (best 0.89) |
| 8XNP | Respiratory complex Peripheral Arm of CI, close form B, focus-refined map of type IA, Wild type… | electron microscopy | A | 3PE | 4 (best 0.88) |
| 8XNS | Respiratory complex Peripheral Arm of CI, close form B, focus-refined map of type IB, Wild type… | electron microscopy | A | 3PE | 4 (best 0.89) |
| 8XNT | Respiratory complex Peripheral Arm of CI, close form C, focus-refined map of type IB, Wild type… | electron microscopy | A | 3PE | 3 (best 0.86) |
| 8XNU | Respiratory complex Peripheral Arm of CI, open form A, focus-refined map of type IB, Wild type… | electron microscopy | A | 3PE | 1 (best 0.77) |
| 8XNV | Respiratory complex Peripheral Arm of CI, close form A, focus-refined map of type II, Wild type… | electron microscopy | A | 3PE, PC1 | 4 (best 0.88) |
| 8XNW | Respiratory complex Peripheral Arm of CI, close form B, focus-refined map of type II, Wild type… | electron microscopy | A | — | 2 (best 0.87) |
| 8XNX | Respiratory complex Peripheral Arm of CI, open form A, focus-refined map of type II, Wild type… | electron microscopy | A | 3PE, PC1 | 3 (best 0.89) |
| 8XNY | Respiratory complex Peripheral Arm of CI, open form B, focus-refined map of type II, Wild type… | electron microscopy | A | 3PE, PC1 | 2 (best 0.83) |
| 8XNZ | Respiratory complex Peripheral Arm of CI, close form A, focus-refined map of type I, PERK -/- mouse… | electron microscopy | A | 3PE | 3 (best 0.89) |
| P03899 | AlphaFold monomer V2.0 prediction for NADH-ubiquinone oxidoreductase chain 3 (P03899) | — | — | — |
Ligands
Elsewhere
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