UniProt P02919
Penicillin-binding protein 1B (P02919)
Penicillin-binding protein 1B (UniProt P02919), EC 2.4.1.129, 3.4.-.-: 22 experimental structures on GenesisL1, 4 ligands bound, 18 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P02919
- Protein
- Penicillin-binding protein 1B
- EC
- 2.4.1.129, 3.4.-.-, 3.4.16.4
- Experimental structures
- 22
- Predicted models
- 0
- Ligands
- 4
- Pockets
- 18 · 3 records with a druggable one
Structures
22 records of P02919 in the MolNFT archive: 22 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3FWL | Crystal Structure of the Full-Length Transglycosylase PBP1b from Escherichia coli | x-ray diffraction | A | — | — |
| 3FWL | Crystal structure of the full-length transglycosylase PBP1B from escherichia COLI | x-ray diffraction | A | — | — |
| 3VMA | Crystal Structure of the Full-Length Transglycosylase PBP1b from Escherichia coli | x-ray diffraction | A | — | — |
| 3VMA | Crystal structure of the full-length transglycosylase PBP1B from escherichia COLI | x-ray diffraction | A | — | — |
| 5FGZ | E. coli PBP1b in complex with FPI-1465 | x-ray diffraction | A | M0E, 5VW | 8 (best 0.73) |
| 5FGZ | E. COLI PBP1B in complex with fpi-1465 | x-ray diffraction | A | — | — |
| 5HL9 | E. coli PBP1b in complex with acyl-ampicillin and moenomycin | x-ray diffraction | A | AIX, M0E | — |
| 5HL9 | E. COLI PBP1B in complex with acyl-ampicillin and moenomycin | x-ray diffraction | A | — | — |
| 5HLA | E. coli PBP1b in complex with acyl-cephalexin and moenomycin | x-ray diffraction | A | M0E | — |
| 5HLA | E. COLI PBP1B in complex with acyl-cephalexin and moenomycin | x-ray diffraction | A | — | — |
| 5HLB | E. coli PBP1b in complex with acyl-aztreonam and moenomycin | x-ray diffraction | A | M0E, AZR | — |
| 5HLB | E. COLI PBP1B in complex with acyl-aztreonam and moenomycin | x-ray diffraction | A | — | — |
| 5HLD | E. coli PBP1b in complex with acyl-CENTA and moenomycin | x-ray diffraction | A | M0E | — |
| 5HLD | E. COLI PBP1B in complex with acyl-centa and moenomycin | x-ray diffraction | A | — | — |
| 6FZK | NMR structure of UB2H, regulatory domain of PBP1b from E. coli | solution nmr | A | — | — |
| 6FZK | NMR structure of UB2H, regulatory domain of PBP1B from E. COLI | solution nmr | A | — | — |
| 6G5R | Structure of the UB2H domain of E.coli PBP1B in complex with LpoB | solution nmr | A | — | 3 (best 0.51) |
| 6G5R | Structure of the UB2H domain of E.COLI PBP1B in complex with lpob | solution nmr | A | — | — |
| 6YN0 | Structure of E. COLI PBP1B with a ftsn peptide activating transglycosylase activity | x-ray diffraction | A | M0E | — |
| 7LQ6 | CryoEM structure of Escherichia coli PBP1b | electron microscopy | A | — | 7 (best 0.77) |
| 7LQ6 | Cryoem structure of escherichia COLI PBP1B | electron microscopy | A | — | — |
| P02919 | AlphaFold monomer V2.0 prediction for penicillin-binding protein 1B (P02919) | — | — | — |
Ligands
- M0E · Moenomycin · in 6 records
- 5VW · [[(3~{R},6~{S})-1-methanoyl-6-[[(3~{S})-pyrrolidin-3-yl]oxycarbamoyl]piperidin-3-yl]amino] hydrogen sulfate · in 1 record
- AIX · (2R,4S)-2-[(1R)-1-{[(2R)-2-amino-2-phenylacetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid · in 1 record
- AZR · 2-({[(1Z)-1-(2-amino-1,3-thiazol-4-yl)-2-oxo-2-{[(2S, 3S)-1-oxo-3-(sulfoamino)butan-2-yl]amino}ethylidene]amino}oxy)-2-methylpropanoic acid · in 1 record
Elsewhere
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