Ligand · AIX
AIX · (2R,4S)-2-[(1R)-1-{[(2R)-2-amino-2-phenylacetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid
AIX, (2R,4S)-2-[(1R)-1-{[(2R)-2-amino-2-phenylacetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid (C16 H21 N3 O4 S, 351.4 g/mol), in the MolNFT structures on GenesisL1: bound in 12 records (9 PDB entries). Every…
- Component
- AIX
- Formula
- C16 H21 N3 O4 S
- Class
- ligand
- Structures
- 12
- PDB entries
- 9
Binding sites
AIX in 12 structures; the first of them:
- 5HL9 · E. coli PBP1b in complex with acyl-ampicillin and moenomycin · AIX A901 · binds GLY509, SER510, LYS513, ASP553, SER572, ASN574, THR682, LYS698 and 6 more
- 5ZQC · Crystal Structure of Penicillin-Binding Protein D2 from Listeria monocytogenes in the… · AIX A301 · binds ALA57, SER58, LYS61, ALA93, VAL94, MET117, SER118, ASN120 and 8 more
- 6VKS · Cryo-electron microscopy structures of a gonococcal multidrug efflux pump illuminate a… · AIX B1106 · binds ASN135, PHE136, ILE139, PHE176, SER275, THR277, VAL607, PHE610
- 7K2Y · Crystal structure of CTX-M-14 E166A/K234R Beta-lactamase in complex with hydrolyzed… · AIX A401 · binds CYS69, SER70, LYS73, ASN104, TYR105, SER130, ASN132, PRO167 and 7 more
- 8AKI · Acyl-enzyme complex of ampicillin bound to deacylation mutant KPC-2 (E166Q) · AIX A301 · binds CYS69, SER70, LYS73, TRP105, SER130, ASN132, GLN166, LEU167 and 9 more
- 8B2V · Millisecond cryo-trapping by the spitrobot crystal plunger, CTX-M-14 E166A Ampicillin, 1… · AIX A301 · binds CYS69, SER70, LYS73, ASN104, TYR105, SER130, ASN132, PRO167 and 7 more
- 8B2W · Millisecond cryo-trapping by the spitrobot crystal plunger, CTX-M-14 E166A, Ampicillin… · AIX A301 · binds CYS69, SER70, LYS73, ASN104, TYR105, SER130, ASN132, PRO167 and 8 more
- 5ZQC · Crystal structure of penicillin-binding protein D2 from listeria monocytogenes in the… · AIX A301 · binds ALA57, SER58, VAL94, MET117, SER118, ASN120, THR223, GLY224 and 2 more
- 6KGW · Crystal structure of penicillin binding protein 3 (PBP3) from mycobacterium tuerculosis… · AIX A704 · binds GLY385, SER386, ALA424, SER441, ASN443, LYS592, THR593, GLY594 and 3 more
- 6PL6 · Structural coordination of polymerization and crosslinking by a peptidoglycan synthase… · AIX B601 · binds SER308, TRP346, SER363, ASN365, THR513, GLY514, THR515, GLU517 and 2 more
- 6VKS · Cryo-electron microscopy structures of a gonococcal multidrug efflux pump illuminate a… · AIX B1106 · binds PHE136, PHE176, THR277, VAL607, PHE610
- 7K2Y · Crystal structure of ctx-M-14 E166A/K234R beta-lactamase in complex with hydrolyzed… · AIX A401 · binds CYS69, SER70, ASN104, TYR105, SER130, ASN132, ASN170, ARG234 and 4 more
Residues it binds most
SER 17, THR 18, ASN 17, GLY 16, LYS 13, PHE 10, ALA 9, ARG 12, VAL 10, CYS 5 (residue and the binding sites it lines).
Found with
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