GL1X · GenesisL1 explorer

Ligand · AIC

AIC · (2S,5R,6R)-6-{[(2R)-2-amino-2-phenylethanoyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

AIC, (2S,5R,6R)-6-{[(2R)-2-amino-2-phenylethanoyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (C16 H19 N3 O4 S, 349.4 g/mol), in the MolNFT structures on GenesisL1: bound in 16 records (8 PDB entries).…

Component
AIC
Formula
C16 H19 N3 O4 S
Class
ligand
Structures
16
PDB entries
8

Binding sites

AIC in 16 structures; the first of them:

  • 1H8S · Three-dimensional structure of anti-ampicillin single chain Fv fragment complexed with… · AIC A1000 · binds TYR39, GLN92, TYR94, TYR97, LEU99, PHE101, TRP164, ASN166 and 7 more
  • 1NX9 · Acetobacter turbidans alpha-amino acid ester hydrolase S205A mutant complexed with… · AIC A5001 · binds TYR112, ARG117, TYR154, ALA205, GLU207, SER256, GLN257, HIS370 and 2 more
  • 2RDD · X-ray crystal structure of AcrB in complex with a novel transmembrane helix. · AIC A1109 · binds SER96, GLY97, PHE458, GLY460, ARG468
  • 3ITA · Crystal structure of Penicillin-Binding Protein 6 (PBP6) from E. coli in acyl-enzyme… · AIC D501 · binds PRO264, ILE265, PHE271, VAL272, LEU304, LYS305, ALA306, TYR308 and 1 more
  • 3KP3 · Staphylococcus epidermidis in complex with ampicillin · AIC B2001 · binds GLU13, ASN20, THR23, ALA24, LEU27, GLN31, ALA38, GLU39 and 6 more
  • 3NDV · Crystal structure of the N-terminal beta-aminopeptidase BapA in complex with ampicillin · AIC A375 · binds THR76, GLY77, THR100, GLU133, THR134, LEU135, ASN137, ARG138 and 8 more
  • 4GCP · Crystal Structure of E. coli OmpF porin in complex with Ampicillin · AIC A401 · binds TYR22, TYR32, GLY33, PHE118, GLY119, GLY120, ASP121, ALA123 and 4 more
  • 4KR4 · Salmonella typhi OmpF complex with Ampicillin · AIC C401 · binds LYS16, ARG20, TYR36, ARG60, ARG77, ASP108, TYR112, PHE113 and 7 more
  • 1H8S · Three-dimensional structure of anti-ampicillin single chain fv fragment complexed with… · AIC A1000 · binds TYR39, GLN92, TYR94, TYR97, LEU99, PHE101, TRP164, ASN166 and 7 more
  • 1NX9 · Acetobacter turbidans alpha-amino acid ester hydrolase S205A mutant complexed with… · AIC A5001 · binds TYR112, ARG117, TYR154, ALA205, GLU207, SER256, GLN257, HIS370 and 2 more
  • 2RDD · X-ray crystal structure of acrb in complex with a novel transmembrane helix. · AIC A1109 · binds SER96, GLY97, PHE458, GLY460, ARG468
  • 3ITA · Crystal structure of penicillin-binding protein 6 (PBP6) from E. COLI in acyl-enzyme… · AIC D501 · binds PRO264, ILE265, PHE271, VAL272, LEU304, LYS305, ALA306, TYR308 and 1 more
  • 3KP3 · Staphylococcus epidermidis in complex with ampicillin · AIC B2001 · binds GLU13, ASN20, THR23, ALA24, LEU27, GLN31, ALA38, GLU39 and 6 more
  • 3NDV · Crystal structure of the N-terminal beta-aminopeptidase bapa in complex with ampicillin · AIC A375 · binds THR76, GLY77, THR100, GLU133, THR134, LEU135, ASN137, ARG138 and 8 more
  • 4GCP · Crystal structure of E. COLI ompf porin in complex with ampicillin · AIC A401 · binds TYR22, TYR32, GLY33, PHE118, GLY119, GLY120, ASP121, ALA123 and 4 more
  • 4KR4 · Salmonella typhi ompf complex with ampicillin · AIC C401 · binds LYS16, ARG20, TYR36, ARG60, ARG77, ASP108, TYR112, PHE113 and 7 more

Residues it binds most

TYR 20, SER 28, ARG 30, GLY 18, LEU 14, ALA 24, ASN 16, THR 12, PHE 22, GLU 20 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion
  • GOL · Glycerol
  • AIX · (2R,4S)-2-[(1R)-1-{[(2R)-2-amino-2-phenylacetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid
  • NDV · (2S,4S)-2-[(1R)-1-{[(2R)-2-amino-2-phenylacetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.