MolNFT v1 · #149619 · protein
Structure of the UB2H domain of E.COLI PBP1B in complex with lpob
6G5R · Penicillin-binding protein 1B: “Structure of the UB2H domain of E.COLI PBP1B in complex with lpob”. Solution nmr, 3 pockets (best druggability 0.51). MolNFT v1 #149619 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6G5R
- Type
- protein
- Length
- 114 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Penicillin-binding protein 1B
- EC
- 2.4.1.129, 3.4.16.4
- UniProt
- P02919
- Pockets
- 3 · best druggability 0.51
Structure
solution nmr · 1 distinct chain · 10% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Penicillin-binding protein 1B (EC 2.4.1.129, 3.4.16.4) | protein | 114 | 10% helix, 24% strand | P02919 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 61 | 0.51 | 0.86 | 24 | empty |
| 2 | 85 | 0.36 | 0.76 | 16 | empty |
| 3 | 75 | 0.34 | 0.75 | 18 | empty |
Compared structures
- 6G5R · Structure of the UB2H domain of E.coli PBP1B in complex with LpoB · the same entry in another collection · chain A against A, TM-score 1.00
- P02919 · AlphaFold monomer V2.0 prediction for penicillin-binding protein 1B (P02919) · a predicted model of the same protein · chain A against A, TM-score 0.53
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P02919
- Elsewhere: RCSB PDB 6G5R · PDBe 6G5R · UniProt P02919
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