UniProt P02557
Tubulin beta chain (P02557)
Tubulin beta chain (UniProt P02557): 10 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 24 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P02557
- Protein
- Tubulin beta chain
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 24 · 3 records with a druggable one
Structures
11 records of P02557 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4FFB | A TOG:alpha/beta-tubulin Complex Structure Reveals Conformation-Based Mechanisms For a Microtubule… | x-ray diffraction | B | — | — |
| 4FFB | A TOG:ALPHA/BETA-tubulin complex structure reveals conformation-based mechanisms for a microtubule… | x-ray diffraction | B | — | — |
| 4U3J | TOG2:alpha/beta-tubulin complex | x-ray diffraction | B | — | — |
| 4U3J | TOG2:ALPHA/BETA-tubulin complex | x-ray diffraction | B | — | — |
| 5W3F | Yeast tubulin polymerized with GTP in vitro | electron microscopy | B | GTP, GDP | — |
| 5W3F | Yeast tubulin polymerized with GTP in vitro | electron microscopy | B | GTP, GDP | — |
| 5W3H | Yeast microtubule stabilized with epothilone | electron microscopy | B | GTP, GDP, EP | 9 (best 0.82) |
| 5W3H | Yeast microtubule stabilized with epothilone | electron microscopy | B | GTP, GDP, EP | — |
| 5W3J | Yeast microtubule stabilized with Taxol assembled from mutated tubulin | electron microscopy | B | GTP, GDP, TA1 | 10 (best 0.83) |
| 5W3J | Yeast microtubule stabilized with taxol assembled from mutated tubulin | electron microscopy | B | GTP, GDP, TA1 | — |
| P02557 | AlphaFold monomer V2.0 prediction for tubulin beta chain (P02557) | predicted | A | — | 5 (best 0.58) |
Ligands
Experiment against prediction
- 4U3J chain B against the predicted model P02557: TM-score 0.99, RMSD 0.70 Å
- 4U3J chain B against the predicted model P02557: TM-score 0.99, RMSD 0.70 Å
- 4FFB chain B against the predicted model P02557: TM-score 0.99, RMSD 0.80 Å
- 4FFB chain B against the predicted model P02557: TM-score 0.99, RMSD 0.80 Å
- 5W3H chain B against the predicted model P02557: TM-score 0.97, RMSD 1.33 Å
- 5W3H chain B against the predicted model P02557: TM-score 0.97, RMSD 1.33 Å
- 5W3F chain B against the predicted model P02557: TM-score 0.96, RMSD 1.51 Å
- 5W3F chain B against the predicted model P02557: TM-score 0.96, RMSD 1.51 Å
- 5W3J chain B against the predicted model P02557: TM-score 0.96, RMSD 1.53 Å
- 5W3J chain B against the predicted model P02557: TM-score 0.96, RMSD 1.53 Å
Elsewhere
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