UniProt P01892
HLA class I histocompatibility antigen, A-2 alpha chain (P01892)
HLA class I histocompatibility antigen, A-2 alpha chain (UniProt P01892): 510 experimental structures on GenesisL1, 9 ligands bound, 239 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P01892
- Protein
- HLA class I histocompatibility antigen, A-2 alpha chain
- Experimental structures
- 510
- Predicted models
- 0
- Ligands
- 9
- Pockets
- 239 · 25 records with a druggable one
Structures
510 records of P01892 in the MolNFT archive: 510 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1AKJ | Complex of the human MHC class I glycoprotein HLA-A2 and the T cell coreceptor CD8 | x-ray diffraction | A | — | — |
| 1AKJ | Complex of the human MHC class I glycoprotein HLA-A2 and the T cell coreceptor CD8 | x-ray diffraction | A | — | — |
| 1AO7 | Complex between human T-cell receptor, viral peptide (tax), and HLA-a 0201 | x-ray diffraction | A | — | — |
| 1AO7 | Complex between human T-cell receptor, viral peptide (tax), and HLA-a 0201 | x-ray diffraction | A | — | — |
| 1AQD | HLA-DR1 (dra, DRB1 0101) human class II histocompatibility protein (extracellular domain) complexed… | x-ray diffraction | C, F, I, L | — | — |
| 1AQD | HLA-DR1 (dra, DRB1 0101) human class II histocompatibility protein (extracellular domain) complexed… | x-ray diffraction | C, F, I, L | — | — |
| 1B0G | Class I histocompatibility antigen (HLA-A2.1)/BETA 2-MICROGLOBULIN/PEPTIDE P1049 complex | x-ray diffraction | A, D | — | — |
| 1B0G | Class I histocompatibility antigen (HLA-A2.1)/BETA 2- MICROGLOBULIN/PEPTIDE P1049 complex | x-ray diffraction | A, D | — | — |
| 1B0R | Crystal structure of HLA-A*0201 complexed with a peptide with the carboxyl-terminal group… | x-ray diffraction | A | — | — |
| 1B0R | Crystal structure of HLA-A*0201 complexed with a peptide with the carboxyl-terminal group… | x-ray diffraction | A | — | — |
| 1BD2 | Complex between human T-cell receptor B7, viral peptide (tax) and MHC class I molecule HLA-a 0201 | x-ray diffraction | A | — | — |
| 1BD2 | Complex between human T-cell receptor B7, viral peptide (tax) and MHC class I molecule HLA-a 0201 | x-ray diffraction | A | — | — |
| 1DUY | Crystal structure of HLA-A*0201/OCTAMERIC tax peptide complex | x-ray diffraction | A, D | — | — |
| 1DUY | Crystal structure of HLA-A*0201/OCTAMERIC tax peptide complex | x-ray diffraction | A, D | — | — |
| 1DUZ | Human class I histocompatibility antigen (HLA-a 0201) in complex with a nonameric peptide from… | x-ray diffraction | A, D | — | — |
| 1DUZ | Human class I histocompatibility antigen (HLA-a 0201) in complex with a nonameric peptide from… | x-ray diffraction | A, D | — | — |
| 1EEY | Crystal Structure Determination Of HLA A2 Complexed to Peptide GP2 with the substitution… | x-ray diffraction | A, D | — | — |
| 1EEY | Crystal structure determination of HLA A2 complexed to peptide GP2 with the substitution… | x-ray diffraction | A, D | — | — |
| 1EEZ | Crystal Structure Determination of HLA-A2.1 Complexed to GP2 Peptide Variant(I2L/V5L) | x-ray diffraction | A, D | — | — |
| 1EEZ | Crystal structure determination of HLA-A2.1 complexed to GP2 peptide VARIANT(I2L/V5L) | x-ray diffraction | A, D | — | — |
| 1HHG | The antigenic identity of PEPTIDE(SLASH)MHC complexes: a comparison of the conformation of five… | x-ray diffraction | A, D | — | — |
| 1HHG | The antigenic identity of PEPTIDE(SLASH)MHC complexes: a comparison of the conformation of five… | x-ray diffraction | A, D | — | — |
| 1HHH | The antigenic identity of PEPTIDE(SLASH)MHC complexes: a comparison of the conformation of five… | x-ray diffraction | A | — | — |
| 1HHH | The antigenic identity of PEPTIDE(SLASH)MHC complexes: a comparison of the conformation of five… | x-ray diffraction | A | — | — |
| 1HHI | The antigenic identity of PEPTIDE(SLASH)MHC complexes: a comparison of the conformation of five… | x-ray diffraction | A, D | — | — |
| 1HHI | The antigenic identity of PEPTIDE(SLASH)MHC complexes: a comparison of the conformation of five… | x-ray diffraction | A, D | — | — |
| 1HHJ | The antigenic identity of PEPTIDE(SLASH)MHC complexes: a comparison of the conformation of five… | x-ray diffraction | A, D | — | — |
| 1HHJ | The antigenic identity of PEPTIDE(SLASH)MHC complexes: a comparison of the conformation of five… | x-ray diffraction | A, D | — | — |
| 1HHK | The antigenic identity of PEPTIDE(SLASH)MHC complexes: a comparison of the conformation of five… | x-ray diffraction | A, D | — | — |
| 1HHK | The antigenic identity of PEPTIDE(SLASH)MHC complexes: a comparison of the conformation of five… | x-ray diffraction | A, D | — | — |
| 1HLA | Structure of the human class I histocompatibility antigen, HLA-A2 | x-ray diffraction | A | — | — |
| 1HLA | Structure of the human class I histocompatibility antigen, HLA-A2 | x-ray diffraction | A | — | — |
| 1I1F | Crystal structure of human class i mhc (hla-a2.1) complexed with beta 2-microglobulin and hiv-rt… | x-ray diffraction | A, D | — | — |
| 1I1F | Crystal structure of human class I MHC (HLA-A2.1) complexed with beta 2-microglobulin and HIV-rt… | x-ray diffraction | A, D | — | — |
| 1I1Y | Crystal structure of human class I MHC (HLA-A2.1) complexed with beta 2-microglobulin and HIV-rt… | x-ray diffraction | A, D | — | — |
| 1I1Y | Crystal structure of human class I MHC (HLA-A2.1) complexed with beta 2-microglobulin and HIV-rt… | x-ray diffraction | A, D | — | — |
| 1I4F | Crystal structure of HLA-A*0201/MAGE-A4-peptide complex | x-ray diffraction | A | — | — |
| 1I4F | Crystal structure of HLA-A*0201/MAGE-A4-peptide complex | x-ray diffraction | A | — | — |
| 1I7R | Crystal structure of class I MHC A2 in complex with peptide P1058 | x-ray diffraction | A, D | — | — |
| 1I7R | Crystal structure of class I MHC A2 in complex with peptide P1058 | x-ray diffraction | A, D | — | — |
| 1I7T | Crystal structure of class I MHC A2 in complex with peptide P1049-5V | x-ray diffraction | A, D | — | — |
| 1I7T | Crystal structure of class I MHC A2 in complex with peptide P1049-5V | x-ray diffraction | A, D | — | — |
| 1I7U | Crystal structure of class I MHC A2 in complex with peptide P1049-6V | x-ray diffraction | A, D | — | — |
| 1I7U | Crystal structure of class I MHC A2 in complex with peptide P1049-6V | x-ray diffraction | A, D | — | — |
| 1IM3 | Crystal Structure of the human cytomegalovirus protein US2 bound to the MHC class I molecule… | x-ray diffraction | A, E, I, M | — | — |
| 1IM3 | Crystal structure of the human cytomegalovirus protein US2 bound to the MHC class I molecule… | x-ray diffraction | A, E, I, M | — | — |
| 1JF1 | Crystal structure of HLA-A2*0201 in complex with a decameric altered peptide ligand from the… | x-ray diffraction | A | — | — |
| 1JF1 | Crystal structure of HLA-A2*0201 in complex with a decameric altered peptide ligand from the… | x-ray diffraction | A | — | — |
| 1JHT | Crystal structure of HLA-A2*0201 in complex with a nonameric altered peptide ligand (ALGIGILTV)… | x-ray diffraction | A | — | — |
| 1JHT | Crystal structure of HLA-A2*0201 in complex with a nonameric altered peptide ligand (algigiltv)… | x-ray diffraction | A | — | — |
| 1LP9 | Xenoreactive complex AHIII 12.2 TCR bound to p1049/HLA-A2.1 | x-ray diffraction | A, H | — | — |
| 1LP9 | Xenoreactive complex ahiii 12.2 TCR bound to P1049/HLA-A2.1 | x-ray diffraction | A, H | — | — |
| 1OGA | A structural basis for immunodominant human T-cell receptor recognition. | x-ray diffraction | A | — | — |
| 1OGA | A structural basis for immunodominant human T-cell receptor recognition. | x-ray diffraction | A | — | — |
| 1P7Q | Crystal Structure of HLA-A2 Bound to LIR-1, a Host and Viral MHC Receptor | x-ray diffraction | A | — | — |
| 1P7Q | Crystal structure of HLA-A2 bound to lir-1, a host and viral MHC receptor | x-ray diffraction | A | — | — |
| 1QEW | Human class I histocompatibility antigen (HLA-a 0201) complex with a nonameric peptide from… | x-ray diffraction | A | — | — |
| 1QEW | Human class I histocompatibility antigen (HLA-a 0201) complex with a nonameric peptide from… | x-ray diffraction | A | — | — |
| 1QR1 | Poor binding of a her-2/NEU epitope (GP2) to HLA-A2.1 is due to a lack of interactions in the… | x-ray diffraction | A, D | — | — |
| 1QR1 | Poor binding of a her-2/NEU epitope (GP2) to HLA-A2.1 is due to a lack of interactions in the… | x-ray diffraction | A, D | — | — |
450 records more on the page itself.
Ligands
- SO4 · Sulfate ion · in 30 records
- NA · Sodium ion · in 3 records
- CL · Chloride ion · in 2 records
- K · Potassium ion · in 2 records
- SCN · Thiocyanate ion · in 2 records
- CA · Calcium ion · in 1 record
- CO · Cobalt (II) ion · in 1 record
- MG · Magnesium ion · in 1 record
- P4G · 1-ethoxy-2-(2-ethoxyethoxy)ethane · in 1 record
Experiment against prediction
- 6D7G chain A against the predicted model P61769: TM-score 0.26, RMSD 0.96 Å
- 6APN chain A against the predicted model P61769: TM-score 0.26, RMSD 1.26 Å
- 6APN chain B against the predicted model P61769: TM-score 0.26, RMSD 0.97 Å
- 6E1I chain A against the predicted model P01887: TM-score 0.25, RMSD 1.00 Å
Elsewhere
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