UniProt P00514
cAMP-dependent protein kinase type I-alpha regulatory subunit (P00514)
cAMP-dependent protein kinase type I-alpha regulatory subunit (UniProt P00514): 45 experimental structures on GenesisL1, 3 ligands bound, 79 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P00514
- Protein
- cAMP-dependent protein kinase type I-alpha regulatory subunit
- Experimental structures
- 45
- Predicted models
- 0
- Ligands
- 3
- Pockets
- 79 · 5 records with a druggable one
Structures
45 records of P00514 in the MolNFT archive: 45 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1NE4 | Crystal Structure of Rp-cAMP Binding R1a Subunit of cAMP-dependent Protein Kinase | x-ray diffraction | A | — | — |
| 1NE4 | Crystal structure of rp-camp binding R1A subunit of camp- dependent protein kinase | x-ray diffraction | A | — | — |
| 1NE6 | Crystal structure of Sp-cAMP binding R1a subunit of cAMP-dependent protein kinase | x-ray diffraction | A | — | — |
| 1NE6 | Crystal structure of sp-camp binding R1A subunit of camp- dependent protein kinase | x-ray diffraction | A | — | — |
| 1RGS | Regulatory subunit of camp dependent protein kinase | x-ray diffraction | A | — | — |
| 1RGS | Regulatory subunit of camp dependent protein kinase | x-ray diffraction | A | — | — |
| 1RL3 | Crystal structure of cAMP-free R1a subunit of PKA | x-ray diffraction | A, B | — | — |
| 1RL3 | Crystal structure of camp-free R1A subunit of PKA | x-ray diffraction | A, B | — | — |
| 2EZW | Solution structure of the docking and dimerization domain of the type I alpha regulatory subunit of… | solution nmr | A, B | — | — |
| 2EZW | Solution structure of the docking and dimerization domain of the type I alpha regulatory subunit of… | solution nmr | A, B | — | — |
| 2QCS | A complex structure between the Catalytic and Regulatory subunit of Protein Kinase A that… | x-ray diffraction | B | — | — |
| 2QCS | A complex structure between the catalytic and regulatory subunit of protein kinase a that… | x-ray diffraction | B | — | — |
| 3FHI | Crystal structure of a complex between the catalytic and regulatory (RI{alpha}) subunits of PKA | x-ray diffraction | B | — | — |
| 3FHI | Crystal structure of a complex between the catalytic and regulatory (RI{ALPHA}) subunits of PKA | x-ray diffraction | B | — | — |
| 3IIA | Crystal structure of apo (91-244) RIa subunit of cAMP-dependent protein kinase | x-ray diffraction | A | — | — |
| 3IIA | Crystal structure of apo (91-244) ria subunit of camp-dependent protein kinase | x-ray diffraction | A | — | — |
| 3IM3 | Crystal structure of PKA RI alpha dimerization/docking domain | x-ray diffraction | A | — | — |
| 3IM3 | Crystal structure of PKA ri alpha DIMERIZATION/DOCKING domain | x-ray diffraction | A | — | — |
| 3IM4 | Crystal structure of cAMP-dependent Protein Kinase A Regulatory Subunit I alpha in complex with… | x-ray diffraction | A, B | — | — |
| 3IM4 | Crystal structure of camp-dependent protein kinase a regulatory subunit I alpha in complex with… | x-ray diffraction | A, B | — | — |
| 3PLQ | Crystal structure of PKA type I regulatory subunit bound with Rp-8-Br-cAMPS | x-ray diffraction | A | — | — |
| 3PLQ | Crystal structure of PKA type I regulatory subunit bound with rp-8-br- camps | x-ray diffraction | A | — | — |
| 3PNA | Crystal Structure of cAMP bound (91-244)RIa Subunit of cAMP-dependent Protein Kinase | x-ray diffraction | A, B | — | — |
| 3PNA | Crystal structure of camp bound (91-244)RIA subunit of camp-dependent protein kinase | x-ray diffraction | A, B | — | — |
| 3PVB | Crystal structure of (73-244)RIa:C holoenzyme of cAMP-dependent Protein kinase | x-ray diffraction | B | — | — |
| 3PVB | Crystal structure of (73-244)RIA:C holoenzyme of camp-dependent protein kinase | x-ray diffraction | B | — | — |
| 4JV4 | Crystal Structure of RIalpha(91-379) bound to HE33, a N6 di-propyl substituted cAMP analog | x-ray diffraction | A | — | — |
| 4JV4 | Crystal structure of RIALPHA(91-379) bound to HE33, a N6 di-propyl substituted camp analog | x-ray diffraction | A | — | — |
| 4MX3 | Crystal Structure of PKA RIalpha Homodimer | x-ray diffraction | A, B | — | — |
| 4MX3 | Crystal structure of PKA rialpha homodimer | x-ray diffraction | A, B | — | — |
| 4X6R | An Isoform-specific Myristylation Switch Targets RIIb PKA Holoenzymes to Membranes | x-ray diffraction | B | — | — |
| 4X6R | An isoform-specific myristylation switch targets riib PKA holoenzymes to membranes | x-ray diffraction | B | — | — |
| 5HVZ | Crystal structure of smAKAP AKB domain bound RIa dimerization/docking (D/D) complex at 2.0 A… | x-ray diffraction | A, B | — | — |
| 5HVZ | Crystal structure of smakap akb domain bound ria DIMERIZATION/DOCKING (D/D) complex at 2.0 a… | x-ray diffraction | A, B | — | — |
| 5JR7 | Crystal structure of an ACRDYS heterodimer [RIa(92-365):C] of PKA | x-ray diffraction | B, D | — | 13 (best 0.83) |
| 5JR7 | Crystal structure of an acrdys heterodimer [RIA(92-365):C] of PKA | x-ray diffraction | B, D | — | — |
| 6BYR | Structures of the PKA RI alpha holoenzyme with the FLHCC driver J-PKAc alpha or native PKAc alpha | x-ray diffraction | B, D | ATP | 13 (best 0.81) |
| 6BYR | Structures of the PKA ri alpha holoenzyme with the flhcc driver J-pkac alpha or native pkac alpha | x-ray diffraction | B, D | ATP | — |
| 6BYS | Structures of the PKA RI alpha holoenzyme with the FLHCC driver J-PKAc alpha or native PRKAc alpha | x-ray diffraction | B, D, F, H | — | 16 (best 0.81) |
| 6BYS | Structures of the PKA ri alpha holoenzyme with the flhcc driver J-pkac alpha or native prkac alpha | x-ray diffraction | B, D, F, H | — | — |
| 6NO7 | Crystal Structure of the full-length wild-type PKA RIa Holoenzyme | x-ray diffraction | B, D, F, H | MG, ATP | 17 (best 0.83) |
| 6NO7 | Crystal structure of the full-length wild-type PKA ria holoenzyme | x-ray diffraction | B, D, F, H | ATP | — |
| 7LZ4 | Crystal structure of A211D mutant of Protein Kinase A RIa subunit, a Carney Complex mutation | x-ray diffraction | A, B, C, D, E, F, G, H | CMP | 20 (best 0.73) |
| 7LZ4 | Crystal structure of A211D mutant of protein kinase a ria subunit, a carney complex mutation | x-ray diffraction | A, B, C, D, E, F, G, H | CMP | — |
| P00514 | AlphaFold monomer V2.0 prediction for camp-dependent protein kinase type I-alpha regulatory subunit… | — | — | — |
Ligands
Elsewhere
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