UniProt O43583
Density-regulated protein (O43583)
Density-regulated protein (UniProt O43583): 9 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O43583
- Protein
- Density-regulated protein
- Experimental structures
- 9
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 11 · 3 records with a druggable one
Structures
10 records of O43583 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5ONS | Crystal structure of the minimal DENR-MCTS1 complex | x-ray diffraction | B | ZN | — |
| 5ONS | Crystal structure of the minimal denr-MCTS1 complex | x-ray diffraction | B | ZN | — |
| 5VYC | Crystal structure of the human 40S ribosomal subunit in complex with DENR-MCT-1. | x-ray diffraction | l1, l2, l3, l4, l5, l6 | — | 1 (best 0.87) |
| 6MS4 | Crystal structure of the DENR-MCT-1 complex | x-ray diffraction | B | ZN | 1 (best 0.37) |
| 6MS4 | Crystal structure of the denr-mct-1 complex | x-ray diffraction | B | ZN | — |
| 6VPQ | Crystal structure of the C-terminal domain of DENR | x-ray diffraction | A, B, C, D, E, F | MG, CA | 8 (best 0.84) |
| 6VPQ | Crystal structure of the C-terminal domain of denr | x-ray diffraction | A, B, C, D, E, F | MG, CA | — |
| 6VPR | Crystal structure of the C-terminal domain of DENR | x-ray diffraction | A, B | SO4, HG, PO4 | 1 (best 0.71) |
| 6VPR | Crystal structure of the C-terminal domain of denr | x-ray diffraction | A, B | SO4, HG, PO4 | — |
| O43583 | AlphaFold monomer V2.0 prediction for density-regulated protein (O43583) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6MS4 chain B against the predicted model O43583: TM-score 0.90, RMSD 0.67 Å
- 6MS4 chain B against the predicted model O43583: TM-score 0.90, RMSD 0.67 Å
- 6VPR chain A against the predicted model O43583: TM-score 0.78, RMSD 1.17 Å
- 6VPR chain A against the predicted model O43583: TM-score 0.78, RMSD 1.17 Å
- 6VPR chain B against the predicted model O43583: TM-score 0.77, RMSD 1.17 Å
- 6VPR chain B against the predicted model O43583: TM-score 0.77, RMSD 1.17 Å
- 6VPQ chain D against the predicted model O43583: TM-score 0.75, RMSD 1.81 Å
- 6VPQ chain D against the predicted model O43583: TM-score 0.75, RMSD 1.81 Å
- 6VPQ chain E against the predicted model O43583: TM-score 0.75, RMSD 1.89 Å
- 6VPQ chain E against the predicted model O43583: TM-score 0.75, RMSD 1.89 Å
Elsewhere
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