UniProt O13033
Recombination activating gene 1 - MBP chimera (O13033)
Recombination activating gene 1 - MBP chimera (UniProt O13033), EC 2.3.2.27: 22 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 74 pockets. Binding sites, druggability and experiment against…
- UniProt
- O13033
- Protein
- Recombination activating gene 1 - MBP chimera
- EC
- 2.3.2.27
- Experimental structures
- 22
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 74 · 5 records with a druggable one
Structures
23 records of O13033 in the MolNFT archive: 22 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3JBW | Cryo-electron microscopy structure of RAG Paired Complex (with NBD, no symmetry) | electron microscopy | A, C | — | — |
| 3JBW | Cryo-electron microscopy structure of rag paired complex (with nbd, no symmetry) | electron microscopy | A, C | — | — |
| 3JBX | Cryo-electron microscopy structure of RAG Signal End Complex (C2 symmetry) | electron microscopy | A, C | — | — |
| 3JBX | Cryo-electron microscopy structure of rag signal end complex (C2 symmetry) | electron microscopy | A, C | — | — |
| 3JBY | Cryo-electron microscopy structure of RAG Paired Complex (C2 symmetry) | electron microscopy | A, C | — | — |
| 3JBY | Cryo-electron microscopy structure of rag paired complex (C2 symmetry) | electron microscopy | A, C | — | — |
| 6DBI | Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS nicked DNA intermediates | electron microscopy | C, A | ZN, CA | 18 (best 0.87) |
| 6DBI | Cryo-EM structure of rag in complex with 12-rss and 23-rss nicked DNA intermediates | electron microscopy | C, A | ZN, CA | — |
| 6DBJ | Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS nicked DNA intermediates | electron microscopy | A, C | ZN, CA | 16 (best 0.87) |
| 6DBJ | Cryo-EM structure of rag in complex with 12-rss and 23-rss nicked DNA intermediates | electron microscopy | A, C | ZN, CA | — |
| 6DBL | Cryo-EM structure of rag in complex with 12-rss and 23-rss substrate dnas | electron microscopy | A, C | ZN, CA | — |
| 6DBO | Cryo-EM structure of rag in complex with 12-rss and 23-rss substrate dnas | electron microscopy | A, C | ZN, CA | — |
| 6DBQ | Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs | electron microscopy | A, C | ZN, CA | 15 (best 0.86) |
| 6DBQ | Cryo-EM structure of rag in complex with 12-rss and 23-rss substrate dnas | electron microscopy | A, C | ZN, CA | — |
| 6DBR | Cryo-EM structure of RAG in complex with one melted RSS and one unmelted RSS | electron microscopy | A, C | ZN, CA | 17 (best 0.86) |
| 6DBR | Cryo-EM structure of rag in complex with one melted rss and one unmelted rss | electron microscopy | A, C | ZN, CA | — |
| 6DBT | Cryo-EM structure of rag in complex with 12-rss and 23-rss substrate dnas | electron microscopy | A, C | ZN, CA | — |
| 6DBU | Cryo-EM structure of rag in complex with 12-rss and 23-rss substrate dnas | electron microscopy | A, C | ZN, CA | — |
| 6DBV | Cryo-EM structure of rag in complex with 12-rss and 23-rss substrate dnas | electron microscopy | A, C | ZN, CA | — |
| 6DBW | Cryo-EM structure of RAG in complex with 12-RSS substrate DNA | electron microscopy | A, C | ZN, CA | — |
| 6DBW | Cryo-EM structure of rag in complex with 12-rss substrate DNA | electron microscopy | A, C | ZN, CA | — |
| 6DBX | Cryo-EM structure of rag in complex with 12-rss substrate DNA | electron microscopy | A, C | ZN, CA | — |
| O13033 | AlphaFold monomer V2.0 prediction for V(D)J recombination-activating protein 1 (O13033) | predicted | A | — | 8 (best 0.74) |
Ligands
Experiment against prediction
- 6DBJ chain C against the predicted model O13033: TM-score 0.99, RMSD 0.66 Å
- 3JBY chain A against the predicted model O13033: TM-score 0.99, RMSD 0.65 Å
- 3JBY chain A against the predicted model O13033: TM-score 0.99, RMSD 0.65 Å
- 6DBJ chain A against the predicted model O13033: TM-score 0.99, RMSD 0.66 Å
- 6DBJ chain A against the predicted model O13033: TM-score 0.99, RMSD 0.66 Å
- 3JBX chain A against the predicted model O13033: TM-score 0.99, RMSD 0.65 Å
- 3JBX chain A against the predicted model O13033: TM-score 0.99, RMSD 0.65 Å
- 6DBO chain A against the predicted model O13033: TM-score 0.99, RMSD 0.93 Å
- 6DBR chain C against the predicted model O13033: TM-score 0.99, RMSD 0.96 Å
- 6DBR chain C against the predicted model O13033: TM-score 0.99, RMSD 0.96 Å
Elsewhere
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