UniProt O00472
RNA polymerase II elongation factor ELL2 (O00472)
RNA polymerase II elongation factor ELL2 (UniProt O00472): 8 experimental structures and 1 predicted model on GenesisL1, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O00472
- Protein
- RNA polymerase II elongation factor ELL2
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 4 · 2 records with a druggable one
Structures
9 records of O00472 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2E5N | Solution structure of the ELL_N2 domain of target of RNA polymerase II elongation factor ELL2 | solution nmr | A | — | — |
| 2E5N | Solution structure of the ELL_N2 domain of target of RNA polymerase II elongation factor ELL2 | solution nmr | A | — | — |
| 5JW9 | The Crystal Structure of ELL2 Oclludin Domain and AFF4 peptide | x-ray diffraction | B | — | — |
| 5JW9 | The crystal structure of ELL2 oclludin domain and AFF4 peptide | x-ray diffraction | B | — | — |
| 7OKX | Structure of active transcription elongation complex Pol II-DSIF (SPT5-KOW5)-ELL2-EAF1 (composite… | electron microscopy | M | — | 2 (best 0.78) |
| 7OKX | Structure of active transcription elongation complex pol II-dsif (SPT5-KOW5)-ELL2-EAF1 (composite… | electron microscopy | M | — | — |
| 7OKY | Structure of active transcription elongation complex Pol II-DSIF-ELL2-EAF1(composite structure) | electron microscopy | M | — | 2 (best 0.79) |
| 7OKY | Structure of active transcription elongation complex pol II-dsif-ELL2- EAF1(COMPOSITE structure) | electron microscopy | M | — | — |
| O00472 | AlphaFold monomer V2.0 prediction for RNA polymerase II elongation factor ELL2 (O00472) | predicted | A | — | — |
Experiment against prediction
- 5JW9 chain B against the predicted model O00472: TM-score 0.97, RMSD 0.76 Å
- 5JW9 chain B against the predicted model O00472: TM-score 0.97, RMSD 0.76 Å
- 2E5N chain A against the predicted model O00472: TM-score 0.88, RMSD 1.44 Å
- 2E5N chain A against the predicted model O00472: TM-score 0.88, RMSD 1.44 Å
- 7OKX chain M against the predicted model O00472: TM-score 0.76, RMSD 2.46 Å
- 7OKY chain M against the predicted model O00472: TM-score 0.76, RMSD 2.46 Å
- 7OKX chain M against the predicted model O00472: TM-score 0.76, RMSD 2.46 Å
- 7OKY chain M against the predicted model O00472: TM-score 0.76, RMSD 2.46 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.