MolNFT v1 · #123816 · protein

The crystal structure of ELL2 oclludin domain and AFF4 peptide

5JW9 · AF4/FMR2 family member 4: “The crystal structure of ELL2 oclludin domain and AFF4 peptide”. X-ray diffraction. MolNFT v1 #123816 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5JW9
Type: protein
Length: 151 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: AF4/FMR2 family member 4; RNA polymerase II elongation factor ELL2
UniProt: Q9UHB7, O00472

Structure

x-ray diffraction · 2 distinct chains · 69% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	AF4/FMR2 family member 4	protein	36	25% helix, 0% strand	Q9UHB7
B	RNA polymerase II elongation factor ELL2	protein	115	83% helix, 0% strand	O00472

Interfaces

1 interface between chains.

A–B · 1535 Å² buried · 15 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 3 modified (engineered).

Compared structures

5JW9 · The Crystal Structure of ELL2 Oclludin Domain and AFF4 peptide · the same entry in another collection · chain A against A, TM-score 1.00
O00472 · AlphaFold monomer V2.0 prediction for RNA polymerase II elongation factor ELL2 (O00472) · a predicted model of the same protein · chain B against A, TM-score 0.97
Q9UHB7 · AlphaFold monomer V2.0 prediction for AF4/FMR2 family member 4 (Q9UHB7) · a predicted model of the same protein · chain A against A, TM-score 0.42

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9UHB7
Every structure of UniProt O00472
Elsewhere: RCSB PDB 5JW9 · PDBe 5JW9 · UniProt Q9UHB7 · UniProt O00472

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