UniProt O00299
Chloride intracellular channel protein 1 (O00299)
Chloride intracellular channel protein 1 (UniProt O00299): 34 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 41 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- O00299
- Protein
- Chloride intracellular channel protein 1
- Experimental structures
- 34
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 41 · 9 records with a druggable one
Structures
35 records of O00299 in the MolNFT archive: 34 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1K0M | Crystal structure of a soluble monomeric form of CLIC1 at 1.4 angstroms | x-ray diffraction | A, B | — | 5 (best 0.49) |
| 1K0M | Crystal structure of a soluble monomeric form of CLIC1 at 1.4 ångströms | x-ray diffraction | A, B | — | 5 (best 0.49) |
| 1K0N | Chloride Intracellular Channel 1 (CLIC1) complexed with glutathione | x-ray diffraction | A, B | GSH | 2 (best 0.56) |
| 1K0N | Chloride intracellular channel 1 (CLIC1) complexed with glutathione | x-ray diffraction | A, B | GSH | 2 (best 0.56) |
| 1K0O | Crystal structure of a soluble form of CLIC1. An intracellular chloride ion channel | x-ray diffraction | A, B | — | 2 (best 0.49) |
| 1K0O | Crystal structure of a soluble form of CLIC1. an intracellular chloride ion channel | x-ray diffraction | A, B | — | 2 (best 0.49) |
| 1RK4 | Crystal Structure of a Soluble Dimeric Form of Oxidised CLIC1 | x-ray diffraction | A, B | — | 7 (best 0.67) |
| 1RK4 | Crystal structure of a soluble dimeric form of oxidised CLIC1 | x-ray diffraction | A, B | — | 7 (best 0.67) |
| 3O3T | Crystal Structure Analysis of M32A mutant of human CLIC1 | x-ray diffraction | A | — | — |
| 3O3T | Crystal structure analysis of M32A mutant of human CLIC1 | x-ray diffraction | A | — | — |
| 3P8W | Crystal Structure Analysis of R29M/E81M double mutant of human CLIC1 | x-ray diffraction | A | — | 1 (best 0.30) |
| 3P8W | Crystal structure analysis of R29M/E81M double mutant of human CLIC1 | x-ray diffraction | A | — | — |
| 3P90 | Crystal Structure Analysis of H207F Mutant of Human CLIC1 | x-ray diffraction | A | — | — |
| 3P90 | Crystal structure analysis of H207F mutant of human CLIC1 | x-ray diffraction | A | — | — |
| 3QR6 | Crystal Structure Analysis of H185F Mutant of Human CLIC1 | x-ray diffraction | A | — | — |
| 3QR6 | Crystal structure analysis of H185F mutant of human CLIC1 | x-ray diffraction | A | — | — |
| 3SWL | Crystal Structure Analysis of H74A Mutant of Human CLIC1 | x-ray diffraction | A | — | — |
| 3SWL | Crystal structure analysis of H74A mutant of human CLIC1 | x-ray diffraction | A | — | — |
| 3TGZ | Crystal Structure Analysis of W35F/H207W Mutant of Human CLIC1 | x-ray diffraction | A, B | — | 1 (best 0.50) |
| 3TGZ | Crystal structure analysis of W35F/H207W mutant of human CLIC1 | x-ray diffraction | A, B | — | — |
| 3UVH | Crystal Structure Analysis of E81M mutant of human CLIC1 | x-ray diffraction | A, B | — | 1 (best 0.68) |
| 3UVH | Crystal structure analysis of E81M mutant of human CLIC1 | x-ray diffraction | A, B | — | — |
| 4IQA | Crystal Structure Analysis of the E228L Mutant of Human CLIC1 | x-ray diffraction | A, B | — | 1 (best 0.60) |
| 4IQA | Crystal structure analysis of the E228L mutant of human CLIC1 | x-ray diffraction | A, B | — | — |
| 4JZQ | Crystal structure of human CLIC1 C24D mutant | x-ray diffraction | A, B | — | 2 (best 0.76) |
| 4JZQ | Crystal structure of human CLIC1 C24D mutant | x-ray diffraction | A, B | — | — |
| 4K0G | Crystal structure of human CLIC1 C24S mutant | x-ray diffraction | A | CA | 1 (best 0.33) |
| 4K0G | Crystal structure of human CLIC1 C24S mutant | x-ray diffraction | A | — | — |
| 4K0N | Crystal structure of human CLIC1 C24A mutant | x-ray diffraction | A | — | — |
| 4K0N | Crystal structure of human CLIC1 C24A mutant | x-ray diffraction | A | — | — |
| 7F8R | Crystal structure of human soluble CLIC1 with catalytic cysteine (Cys24) in sulphonic acid form. | x-ray diffraction | A, B | — | 2 (best 0.69) |
| 7F8R | Crystal structure of human soluble CLIC1 with catalytic cysteine (CYS24) in sulphonic acid form. | x-ray diffraction | A, B | — | — |
| 7FBQ | Human CLIC1 in complex with NSC602247 | x-ray diffraction | A | N70 | — |
| 7FBQ | Human CLIC1 in complex with NSC602247 | x-ray diffraction | A | N70 | — |
| O00299 | AlphaFold monomer V2.0 prediction for chloride intracellular channel protein 1 (O00299) | predicted | A | — | — |
Ligands
Experiment against prediction
- 3UVH chain A against the predicted model O00299: TM-score 0.99, RMSD 0.49 Å
- 3UVH chain A against the predicted model O00299: TM-score 0.99, RMSD 0.49 Å
- 4IQA chain A against the predicted model O00299: TM-score 0.99, RMSD 0.49 Å
- 4IQA chain A against the predicted model O00299: TM-score 0.99, RMSD 0.49 Å
- 4IQA chain B against the predicted model O00299: TM-score 0.99, RMSD 0.54 Å
- 4IQA chain B against the predicted model O00299: TM-score 0.99, RMSD 0.54 Å
- 1K0O chain B against the predicted model O00299: TM-score 0.99, RMSD 0.58 Å
- 1K0O chain B against the predicted model O00299: TM-score 0.99, RMSD 0.58 Å
- 1K0N chain B against the predicted model O00299: TM-score 0.99, RMSD 0.59 Å
- 1K0N chain B against the predicted model O00299: TM-score 0.99, RMSD 0.59 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.